Karolina Socha @karolinazsocha.bsky.social · 01/06/2026Check also Research Briefing: www.nature.com/articles/s41....nature.com 000
Karolina Socha @karolinazsocha.bsky.social · 01/06/2026Huge thanks to all co-authors, especially @carandinilab.net and Josh Siegle for leading this team effort, @wellcometrust.bsky.social , @alleninstitute.org , @hhmijanelia.bsky.social; and to collaborators across AllenInstitute, HHMI Janelia, imec, @uclbrainscience.bsky.social and UW.nature.com 100
Karolina Socha @karolinazsocha.bsky.social · 01/06/2026Neuropixels Opto combines high-resolution electrophysiology and optogenetics, enabling simultaneous recording and manipulation of activity at the level of single neurons and neural populations.nature.com 100
Karolina Socha @karolinazsocha.bsky.social · 01/06/2026🎉 🎉 🎉 Very happy to share that the Neuropixels Opto paper, on which I am a co-first author, is finally out today! @natmethods.nature.com Nature Methods!!! www.nature.com/articles/s41... 1100
Karolina Socha @karolinazsocha.bsky.social · 05/09/2025Huge team effort 🚀 Congrats to all co-authors in @intlbrainlab.bsky.social for making this project and dataset possible! 000
Karolina Socha @karolinazsocha.bsky.social · 05/09/2025From 621,733 neurons recorded with 699 Neuropixels probes across 139 mice in 12 labs, we show that task signals—visual, choice, movement, prior—are distributed widely across the brain. I hope these results inspire future projects. The data are public! 100
Karolina Socha @karolinazsocha.bsky.social · 05/09/2025Thrilled to share that both papers from my postdoc at @ucl.ac.uk at @carandinilab.net, as part of the International Brain Lab collaboration, are now out in @nature.com 🎉 🧠 Brain-wide neural activity during complex behavior: doi.org/10.1038/s415... 🧠 representations of prior: doi.org/10.1038/s415... 120
Reposted by Karolina SochaInternational Brain Laboratory @intlbrainlab.bsky.social · 03/09/2025Two flagship papers from the International Brain Laboratory, now out in @Nature.com: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 + 212569
Reposted by Karolina SochaSonja Hofer @sonjahofer.bsky.social · 05/03/2025Should you stick to your goal, try something else, or give up? Your median raphe nucleus in the brainstem knows and will decide for you 😉. First foray of my lab into foraging, behavioural strategies and exploration. Amazing work from the one and only Mehran Ahmadlou: www.nature.com/articles/s41...nature.comA subcortical switchboard for perseverative, exploratory and disengaged states - NatureBehavioural experiments in mice demonstrate that GABAergic (γ-aminobutyric acid-expressing), glutamatergic and serotonergic neurons in the median raphe nucleus have distinct and complementary function... 812145
Reposted by Karolina SochaCAJAL Training @cajal-training.bsky.social · 05/03/2025⏰ Last days to apply!!⏰ This hands-on course covers: 🦠 Flies/Zebrafish – Optogenetics, 2P imaging 🐭 Mice – 2P/3P imaging, Neuropixels, closed-loop behavior 📅 June 8-27, 2025 | Champalimaud, Lisbon ⏳ Apply by March 7 🔗 loom.ly/OMvqMcE 033
Reposted by Karolina SochaSainsbury Wellcome Centre @sainsburywellcome.bsky.social · 05/03/2025New SWC research identifies the median raphe nucleus (MRN) as a critical hub for flexible switching between behavioural strategies of perseverance, exploration, and disengagement. Full story 🔀 www.sainsburywellcome.org/web/research... 121
Reposted by Karolina SochaSarah Ruediger @ruedigersarah.bsky.social · 05/03/2025🚨 We're looking for an experimentalist to join our team at UCL! 🚨 Whether you’re looking for a postdoc role or want to gain hands-on experience as a research assistant, we’d love to hear from you. If you’re excited about visual circuits, systems neuroscience & mouse behavior, please get in touch! 043
Reposted by Karolina SochaAlex Hyafil @alexhyafil.bsky.social · 30/01/2025Our Barcelona-based summer school, BAMB! (bambschool.org) just opened applications! Come join us: 15-24th July, to learn how to model behavioral data using RL, Bayesian, latent variable models, RNNs, DDMs & more! #BAMB2025bambschool.orgBAMB!Course philosophy Our goal is to teach advanced techniques in model-based analysis of behavior (humans and other animals) to cognitive and computational neuroscientists at PhD and early career levels... 34127
Reposted by Karolina SochaNeuromatch @neuromatch.bsky.social · 24/02/2025🚨 Neuromatch Academy Course Applications are OPEN for 2025!! 🚨 Get your application in early to be a student or teaching assistant for this year’s courses! Applications are due Sunday, March 23. Apply & learn more: neuromatch.io/courses/ #mlsky #compneurosky #ai #climatesolutions #ScienceEdu 🧪 08674
Reposted by Karolina SochaNikolas Karalis @nikolaskaralis.bsky.social · 19/02/2025Very happy to announce the "Paris Circuit Dynamics Conference 2025: Hippocampal–Cortical Circuits: From structure to computation", on 28 - 29 April 2025 at the Paris Brain Institute. You are welcome to register and join us! www.paris-circuits.euparis-circuits.euParis Circuit DynamicsThis two-day conference will bring together leading experts from the Paris region and abroad to discuss the dynamics and neural coding in hippocampal and cortical circuits. The program will focus on ... 02713
Reposted by Karolina SochaClaudia Clopath Lab @clopathlab.bsky.social · 21/02/2025Want to hear more about how feedback can guide learning in RNNs for motor adaptation. Here is our new paper in Nat. Com. with Barbara Feulner and @juangallego.bsky.social www.nature.com/articles/s41...nature.comA neural implementation model of feedback-based motor learning - Nature CommunicationsHow the brain adapts our movements to new conditions remains unclear. Here, the authors show that a recurrent neural network that controls its output using error-based feedback can learn to count... 06719
Reposted by Karolina SochaAlex Williams @itsneuronal.bsky.social · 17/02/2025📣 The 11th Statistical Analysis of Neuronal Data (SAND11) workshop will be held June 11-13, 2025 in New York at the @flatironinstitute.org with generous support from @simonsfoundation.org Submissions for talks+posters are due March 21. See our website for details 👇 sandworkshop.github.iosandworkshop.github.ioSAND - 2025SAND - 2025 03013
Reposted by Karolina SochaChunyu Ann Duan @annduan.bsky.social · 16/02/2025First preprint from our lab! An @jerlich.bsky.social collaboration We developed novel frameworks to study multi-agent decisions in mice. Mice flexibly shift their decision preference under social competition, by integrating real-time self and opponent information! www.biorxiv.org/content/10.1...biorxiv.orgMice dynamically adapt to opponents in competitive multi-player gamesCompeting for resources in dynamic social environments is fundamental for survival, and requires continuous monitoring of both 'self' and 'others' to guide effective choices. Yet our understanding of ... 28622
Reposted by Karolina SochaFanny Cazettes @fannycazettes.bsky.social · 17/02/2025Excited to announce multiple #PhD & #Postdoc positions opening in my lab over the next three years as part of the #ERC Starting grant DIVERSE! Reposts appreciated 😊 #neuroscience #neuroskyence 14140
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025It may take less than 5 years. That technology is just more complex and takes longer to produce than standard Npx probes. 000
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025Project made possible by: @wellcometrust.bsky.social, @alleninstitute.bsky.social, @hhmijanelia.bsky.social, and other funders: IMEC, the NIH BRAIN Initiative, NTNU, Johns Hopkins University, UW, and @uclbrainscience.bsky.social. 020
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025and to the Neuropixels Opto Consortium: @carandinilab.net, Barun Dutta, Tim Harris, Michael Häusser, @sonjahofer.bsky.social, @edvardmoser.bsky.social, Josh Siegle, @steinmetzneuro.bsky.social, and Karel Svoboda. 100
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025to project collaborators: Alexander Ladd, Anna Bowen, Susu Chen, Jennifer Colonell, Anjal Doshi, Bill Karsh, Michael Krumin, Pavel Kulik, Anna Li, Meghan Olsen, Zhiwen Ye, Christof Koch, Jonathan T. Ting 100
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025Huge kudos to the imec team: Pieter Neutens, Jan Putzeys, John O'Callaghan, Harrie A.C. Tilmans, and Marleen Welkenhuysen 100
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025These probes let us evoke activity in neurons near the emitter sites, enabling spatial and temporal control across different depths of the mouse cortex. 100
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025Some snippets of results: we successfully triggered activity in excitatory neurons expressing the red-shifted opsin ChRmine with both long and short light pulses. We show that the probes can be used for precise activation, identification, and manipulation of neuronal populations! 100
Karolina Socha @karolinazsocha.bsky.social · 12/02/2025Thrilled to share our latest work exploring new avenues for combining #Neuropixels with #Optogenetics! Congratulations to co-first author Anna Lakunina, the Neuropixels Opto Consortium and collaborators! www.biorxiv.org/content/10.1... 2224