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Suckjoon Jun’s lab at UCSD

@junlab.bsky.social
465 followers 417 following 102 posts

We study quantitative microbial cell physiology. jun.ucsd.edu “If you want to go fast, go alone. If you want to go far, go together.” -African Proverb

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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 28/09/2026
1/5 Do you use GFP to measure protein abundance? Be very careful. Our new bioRxiv preprint shows that, under translation inhibition, fluorescence can stop tracking how much reporter protein is actually there. Please share widely.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
14/ The kiddo promised he would never do it again. I know better.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
11/ Chelsea galleries, I am sorry we discovered you only in the last weeks of our stay. Thank you for leaving such lasting impressions before it was too late.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
10/ And the American paintings in the museums. Thank you, Mr. Gene, if I remember your name correctly. Picking up the kids from school and going to the Whitney on Fridays to see Hopper and other favorite American paintings was one of the highlights of our year in New York.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
9/ And subway posters. The mask on the gentleman was not our doing. :)
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
8/ Of course, there was unforgettable street art and graffiti.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
7/ And all the little bookstores. I did not expect to find a stack of 'On Writing' in such a tiny shop in the village, packed with New Yorkers.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
6/ Speaking of music, our family was lucky to learn piano at the Greenwich School of Music. We will always remember the piano rooms filled with serene light, and the backyard surrounded by trees and birds.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
5/ And the barbers of Manhattan: disciplined, precise, and among the hardest-working people I saw in the city. My hat is off to you.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
3/ You gave us four magnificent seasons. You showed our California-born children leaves turning color and real snow for the first time in their lives. They did not even seem to mind the brutal cold, even when it emptied the streets of New Yorkers.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 24/06/2026
1/ Goodbye, New York. We are going to miss you.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/06/2026
8/ In hindsight this isn't surprising. Ecology and evolutionary biology have long emphasized deep diversity across lineages. But the consequence is real: E. coli has been the default model for bacterial physiology. It's time to move beyond it if we want truly general principles.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/06/2026
6/ What makes this more than one bacterium is the phylogeny. Both lineages use (p)ppGpp, but not in the same way. The Proteobacterial solution, exemplified by E. coli, acts directly on RNA polymerase. In Firmicutes, the control we describe is routed through GTP instead.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/06/2026
5/ Why would a cell hold its growth below capacity? Because the setting that buys faster growth costs survival. GTP up: faster growth, dies under antibiotics. GTP down: slower growth, endures. Wild-type sits at a regulated balance. Growth and survival pull against each other.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/06/2026
4/ The result is a cell growing slower than the standard picture predicts. And the finding I keep coming back to: we could undo it. By tuning one internal signal, GTP, we restored fast, near-optimal growth under the antibiotic. The slow growth wasn't a trap. It was regulated.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/06/2026
3/ We tested whether it holds in Bacillus subtilis, which solves the same problem with different wiring. It doesn't, in an instructive way. Block translation and E. coli reorganizes its proteome to cope. B. subtilis barely moves its proteome but throttles amino acid synthesis.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/06/2026
1/ Out today in Science (@science.org): a result a decade in the making, and one that changed how I think about what cells are doing when they grow. We found a bacterium that grows slower than it could. And we found the molecular switch that lets us reverse it.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 15/05/2026
A future scholar (bottom left) at Arvind Murugan (@amurugan.bsky.social, top right)’s physical learning seminar at the Flatiron Institute in NYC today.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 15/02/2026
To all graduate students — and all of us in academia. www.nytimes.com/2026/02/15/w...
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 16/12/2025
Excited to announce that our Econophysiology workshop has been accepted at the BIRS in 2027 🇨🇦 Co-organized with Hidde de Jong, Edda Klipp, & Matt Scott, we will bring economists, biologists, and physicists together to build a shared conceptual language across disciplines. Stay tuned! www.birs.ca
https://www.birs.ca/
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 14/12/2025
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 14/12/2025
First snow in Greenwich Village, NYC ❄️
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 15/11/2025
Autumn in the backyard of the Greenwich School of Music.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 07/11/2025
Been awhile — good to see you, Harvard.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 02/11/2025
Autumn is in Greenwich Village
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 31/10/2025
Supplementary Information
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 31/10/2025
Academic job applicant from Greenwich Village…
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 25/10/2025
Hardest working people in Manhattan. Hats off to them.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 20/10/2025
From the Flatiron Institute’s rooftop — autumn is arriving in Manhattan.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 06/10/2025
We celebrated afterwards with friends’ labs — Tzer Han Tan, Hongbo Zhao, and Seungeun Oh among them.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 06/10/2025
Congratulations to Haochen — one of the rare breeds who did both real experiments and theory. He successfully defended his PhD last Friday and is starting his independent Lewis-Sigler Scholar position at Princeton this week. We’ll miss you!
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 02/05/2025
And here comes Hongbo
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 02/05/2025
@tzerhan29.bsky.social is giving our biophysics forum talk on his collaboration with Hongbo Zhao on… “intelligent robots”!
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 04/04/2025
We had a double-feature biophysics forum today, thanks to Vishal Patil (Math) and Christina Hueschen (CDB)! #ucsd_biophysics
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 25/03/2025
Ramin Golestanian (Oxford & MPI Göttingen) visited us and gave an inspiring informal seminar yesterday. 🙏🏻
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 21/03/2025
Another suit and a great talk: Aman Sharma 😃, this time on yeast mitochondria.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 21/03/2025
Haochen Fu from our lab just gave a great talk at the #APS March meeting. He is wearing a… suit!!! 😳
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 12/03/2025
Congratulations to Jihyun In, an undergrad student in our lab, who is a de facto neuro/math/physics triple major, for receiving Physical Sciences Dean’s Undergraduate Award for Excellence!
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 01/03/2025
@saransh162.bsky.social in our lab will give a talk on yeast mitochondria network next tuesday (march 4, 2025). Register for the seminar series here: researchseminars.us17.list-manage.com/subscribe?u=...
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 16/02/2025
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 18/12/2024
This was our first #cellbio2024 meeting, arguable the most exciting+relevant for our research in recent yrs. Thanks to all poster presenters who spent time for us. Immensely proud of our grad students presenting lab's first yeast research on invariant topological properties of mitochondria network.
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 10/12/2024
Saransh will give the lab's first yeast talk since the birth of our lab at the #ASCB meeting 2024 in San Diego (Dec 14-18). Come to the 'Biological Size Control and Scaling' session this Saturday at 9:30 AM! "The topology, shape and size of mitochondrial networks during the cell cycle in yeast"
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 05/12/2024
Since all segmented cells look “okay” to the eye, one might try them as training data sets for deep-learning-based segmentation. What would Omnipose (our favorite U-Net-based SW) produce, if we segment the same images using the two different training data sets? Answer: WYPIWYG 5/N
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 05/12/2024
Importantly, beware of WYPIWYG (What You Put is What You Get). This is particular important for cell-size control research. For example, the Otsu segmented cells are consistently larger than the U-Net segmented cells, typically up to 10% of the cell size. 4/N
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Suckjoon Jun’s lab at UCSD @junlab.bsky.social · 05/12/2024
Do you use mother machine for your research and need help with analysis? Please read (porting our post from X). 🧵 1/N
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