iiinova — where your digital self keeps evolving

Julia Meltzer @juliameltzer.bsky.social · 19/08/2026

Our metatranscriptomics gal @marilysyr.bsky.social killed it at #ISME20 with her talk on #Asgard gene expression in early earth conditions. And she’s only first year PhD!! 🥹 @brendanburns999.bsky.social

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Julia Meltzer @juliameltzer.bsky.social · 13/08/2026

Excited to share what I've been working on with an incredible team! Visualisation of Asgard viruses on cell surfaces and vesicles, and a story of complex viral interactions. Preprint: www.biorxiv.org/content/10.6... @brendanburns999.bsky.social @belindaferrari.bsky.social @xabivc.bsky.social

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Thomas Litfin @tlitfin.bsky.social · 31/10/2025

🧶🧬 We present LMi4Boltz: www.biorxiv.org/content/10.1... Boltz-2 is an excellent open source alternative to AlphaFold3. However, high VRAM use restricts modeling large complexes. Using careful memory management, we increase the Boltz-2 size limit by >60% while maintaining execution speed.

Figure comparing runtime and VRAM utilization between Boltz-2 (baseline), and LMI4Boltz (+memory, and +chunk).
Main plot: runtime (y-axis) versus token count (x-axis), showing that all methods scale similarly, with +memory and +chunk handling larger token counts.
Inset scatterplot: PDB test lDDT scores from Boltz-2 versus LMI4Boltz, showing a strong linear correlation (values near y = x).
Right panels:
– Top bar chart: maximum tokens processable on a 24 GB GPU increase from 1596 (Boltz-2) to 2356 (+memory) and 2660 (+chunk).
– Bottom bar chart: H200 runtime for 1596 tokens remains comparable across methods.

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Kate Michie @kmichie.bsky.social · 31/10/2025

This is amazing work lead by Tom (@tlitfin.bsky.social) in my team. Always trying to get more for less and making computing efficient. So satisfying making science resources go further. Boltz2 is great for protein structure prediction and hopefully LMI4Boltz extends its use. Code on GitHub… 🧶🧬

biorxiv.org

LMI4Boltz: Optimizing VRAM utilization to predict large macromolecular complexes with consumer grade hardware

AlphaFold2 has revolutionized structural biology by enabling the prediction of protein structures approaching experimental quality. AlphaFold3 extends this framework to support modelling broad biomole...

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Julia Meltzer @juliameltzer.bsky.social · 23/07/2025

So excited to finally show the world a project years in the making. A huge group effort with lots of expertise leading to a unique #Asgard syntrophy story. Very fortunate to have been involved in cultivating and analysing this wonderful organism ❤️

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Xabier Vázquez-Campos @xabivc.bsky.social · 23/07/2025

Our new preprint with a new #Asgard from stromatolites (and its Desulfobacterota companion). Complete circularised genomes of both, cool #cryoem images, protein modelling, etc Big group effort with a lot of people involved #archaeasky #archaea www.biorxiv.org/content/10.1...

biorxiv.org

An Asgard archaeon from a modern analog of ancient microbial mats

It has been proposed that eukaryotic cells evolved via symbiosis between sulfate-reducing bacteria and hydrogen-producing archaea. Here we describe a highly enriched culture of a novel Asgard archaeon...

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Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · 23/11/2024

Our Big Fantastic Virus Database (BFVD) is now published NAR! It contains protein structure predictions of major viral clades, enhanced by petabase-scale homology search and it's explorable on the web. 🌐 bfvd.foldseek.com 💾 bfvd.steineggerlab.workers.dev 📄 academic.oup.com/nar/advance-...

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Brett Baker @archaeal.bsky.social · 15/11/2024

New podcast entirely about archaea just started! podcasts.apple.com/us/podcast/a...

podcasts.apple.com

ArchaeaCast

Science Podcast · 3 Episodes · Updated Biweekly

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Julia Meltzer @juliameltzer.bsky.social · 20/11/2024

Join us at the JAMS Sydney community! 🫶🏻♥️

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Alessandro Garritano @alegarritano.bsky.social · 07/11/2023

Finally started migrating from X to bsky and hoping to connect with more people interested in #Bioinformatics 🧬💻. Thanks @amanzanom.bsky.social for all the tips so far and if someone out there have any good tips, please let me know!

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Alessandro Garritano @alegarritano.bsky.social · 14/11/2023

A nice paper on microbial dark matter revealing that in situ devices increase coral's microbes culturability up to 570% is out on iScience 🧪. This device, initially used in soils, has proved to be useful in marine sponges and, now, in corals as well. www.sciencedirect.com/science/arti... #SymbioSky

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Souvik Bhattacharyya @souvik-uthealth.bsky.social · 12/11/2024

Hello Blueskis. Here is a starter pack of General Microbiology. It's a small list currently. Please feel free to self-nominate and I will add you. go.bsky.app/QgSQHJ9

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Katy Brown @thekatybrown.bsky.social · 16/11/2024

I made a quick Starter Pack for scientists working on virus discovery - please reply if you’d like me to add you to the pack (or remove you) or to recommend anyone! #scisky go.bsky.app/HK1wxRb

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Asher Leeks @asherleeks.bsky.social · 17/11/2024

I made a starter pack for researchers who study various aspects of viral sociality. It's woefully incomplete and has lots of room to grow, so do message me if I've missed you! go.bsky.app/3PfgjkP #SocialViruses 🦠 🧪

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Karim Majzoub @karimaj.bsky.social · 18/11/2024

added to Virology and Virus-Host interaction #2 go.bsky.app/6bSDmrW

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