The cellular context decisively shapes genetic circuit performance, but the interplay between host and circuit remains difficult to control rationally. To address this challenge, we replaced the nativ...

The cellular context interacts with genetic circuits, decisively defining their performance. However, contextual dependencies (the interplay between the host and the circuit) are often difficult to en...

The doctoral programme in synthetic biology, run by the Spanish National Research Council, is recruiting 10 doctoral researchers

Designer Biology Conference, 29–31 July 2025 in Newcastle, UK. This event gathers bioengineering and synthetic biology scientists to explore applications like protein engineering and materials.

Designer Biology Conference, 29–31 July 2025 in Newcastle, UK. This event gathers bioengineering and synthetic biology scientists to explore applications like protein engineering and materials.

Tightly regulated promoters with strong inducibility and scalability are highly desirable for biological applications. Here the authors describe ‘Jungle Express’, a EilR repressor-based broad host sys...