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Justine Couble

@ju-couble.bsky.social
48 followers 56 following 1 posts

Just finished my PhD in molecular parasitology at @pasteur.fr 🧬 | Forever curious about parasites 🦠🪱 | Scuba diver & passionate backpacker 🤿🌍| Exploring science and the world, one adventure at a time!

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Reposted by Justine Couble
Sebastian Baumgarten @sebbaumgarten.bsky.social · 30/06/2025
How does the malaria parasite regulate co-expression of genes? By recruiting them into transcription factories, courtesy of MORC et al. A fantastic team effort led by @jessmbryant.bsky.social with Jacques Serizay @singh-parul.bsky.social, @ju-couble.bsky.social @rkoszul.bsky.social
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Reposted by Justine Couble
Nature Microbiology @natmicrobiol.nature.com · 30/06/2025
OUT NOW: High resolution map of the Plasmodium falciparum genome reveals MORC/ApiAP2-mediated links between distant, functionally related genes @jessmbryant.bsky.social sky.social @singh-parul.bsky.social @ju-couble.bsky.social ‬ #MicroSky www.nature.com/articles/s41...
nature.com
High-resolution map of the Plasmodium falciparum genome reveals MORC/ApiAP2-mediated links between distant, functionally related genes - Nature Microbiology
Micro-C provides insights into genome organization in Plasmodium falciparum and defines the machinery used to spatially coordinate antigenic variation and stage-specific genes that are crucial for inf...
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Justine Couble @ju-couble.bsky.social · 17/04/2025
Thrilled to share that the main part of my PhD work is now on bioRxiv! Curious about how Plasmodium regulates its ribosomes? Check it out! Led by @sebbaumgarten.bsky.social with great collaboration from @tizvignolini.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
A metabolism-chromatin axis promotes ribosome heterogeneity in the human malaria parasite
The transmission of the most virulent human malaria parasite, Plasmodium falciparum, relies on its survival in the contrasting environments of the human host and mosquito vector. One of the most fasci...
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Reposted by Justine Couble
Sebastian Baumgarten @sebbaumgarten.bsky.social · 04/04/2025
Ready for the most beautifully sophisticated m6A modification program out there? It’s sex-specific, controls a developmental transition and is temperature-sensitive. Dream team led by Selina, with @ameyasinha.bsky.social @jessmbryant.bsky.social @tizvignolini.bsky.social @ju-couble.bsky.social
doi.org
N6-methyladenosine primes the malaria parasite for transmission
Sudden environmental changes are a recurring challenge for unicellular organisms, but a necessity for many to progress through their lifecycle. To transmit from its human host to mosquito vector, mala...
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Reposted by Justine Couble
Sebastian Baumgarten @sebbaumgarten.bsky.social · 26/03/2025
Malaria parasites are an extreme example of ribosome heterogeneity. But how do they control which ribosomal RNA to express when? Check out this mountain of work led by @ju-couble.bsky.social with @tizvignolini.bsky.social @jessmbryant.bsky.social www.biorxiv.org/content/10.1...
biorxiv.org
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