Reposted by John Ray
📢PUBLISHED @natgenet.nature.com
📰Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks.
By Ching-Huang Ho, John P. Ray and colleagues.
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www.nature.com/articles/s41...
nature.com
Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks - Nature Genetics
Massively parallel reporter assay in primary human CD4+ T cells and bulk and single-cell CRISPR-interference screens identify candidate causal variants linked to autoimmune disease risk that modulate T cell gene expression and proliferation.