iiinova — where your digital self keeps evolving

Jorge Díaz @jorgediazfuentes.bsky.social · 17/08/2026

Inflammatory Astrocytography 🔬🌈 Giving new life to residual images from experiments is a way of looking again at what science leaves unseen. Yesterday, my image won 2nd place at the annual meeting of the Centro Interdisciplinario de Neurociencia de Valparaíso (CINV).Happy to show the beauty of brain

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Jorge Díaz @jorgediazfuentes.bsky.social · 11/05/2026

Very happy to share our new paper, where I am first author, developed at University of Chile. Astrocytes were long overlooked as passive “support” cells, yet they play key roles in brain responses. We explore how neuroinflammation alters astrocyte behaviour. ⚗️🧫🧪 link.springer.com/article/10.1...

link.springer.com

Neuroinflammation-induced downregulation of RAB7 in murine astrocytes disrupts endo-lysosomal homeostasis and induces astrogliosis - Cell Communication and Signaling

Background Neuroinflammation induces astrogliosis, a process marked by astrocyte hypertrophy, increased migration, and altered protein expression. While these changes involve both up- and downregulati...

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Jorge Díaz @jorgediazfuentes.bsky.social · 23/03/2026

Collective migration is not just about leaders at the front, but about coordination across the group. Always exciting to see these dynamics visualized. Many thanks to @jcb.org for featuring our work 🐸🔬🌹

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Jorge Díaz @jorgediazfuentes.bsky.social · 18/03/2026

Collectivity is not uniformity—it’s the coordination of forces under tension. In Xenopus neural crest epithelial clusters, movement emerges from within. From my postdoctoral research: nuclei (red), membranes (magenta), cytoskeleton (green). No internal tension, no collective motion. Tension holds 🐸🔬

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Reposted by Jorge Díaz

Journal of Cell Biology @jcb.org · 28/01/2026

Force coordination distinguishes epithelial and mesenchymal modes of collective #chemotaxis. New study from Jorge Diaz and Roberto Mayor @mayorlab.bsky.social @ucl.ac.uk: rupress.org/jcb/article/... #Migration #motility #Development

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Jorge Díaz @jorgediazfuentes.bsky.social · 22/02/2026

Delighted to see our JCB work (rupress.org/jcb/article/...) beautifully summarized by Bits & Species Mesenchymal and Epithelial-like Xenopus Neural Crest clusters use distinct force architectures to achieve comparable chemotactic performance 🐸🔬🧬🧫 IG feature: www.instagram.com/p/DUlACAJERdA/

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Reposted by Jorge Díaz

Journal of Cell Biology @jcb.org · 18/02/2026

Two ways to move together: force coordination in collective #chemotaxis. Jessica Pacheco & Erica Hutchins @drericabiophd.bsky.social @ctbatucsf.bsky.social discuss study from @jorgediazfuentes.bsky.social & @mayorlab.bsky.social (rupress.org/jcb/article/...) in Spotlight rupress.org/jcb/article/...

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Reposted by Jorge Díaz

Journal of Cell Biology @jcb.org · 21/01/2026

Diaz and @mayorlab.bsky.social show that epithelial and mesenchymal cells navigate chemical cues via fundamentally different force-generating mechanisms, offering new insight into how diverse cell types achieve collective movement during development and disease. rupress.org/jcb/article/...

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Jorge Díaz @jorgediazfuentes.bsky.social · 12/02/2026

Honored to see our work featured in a JCB Spotlight by Pacheco and @drericabiophd.bsky.social (@UCSF). The piece discusses our study revealing distinct force-generating mechanisms in epithelial and mesenchymal collective migration 🔬🐸 Thank you for your careful review of our work! hubs.la/Q042GFYY0

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Jorge Díaz @jorgediazfuentes.bsky.social · 28/01/2026

So proud to share my paper on collective chemotaxis and force coordination in epithelial and mesenchymal cells, developed in the Mayor Lab and now published in JCB. Deeply grateful for everything I learned from Xenopus NC and the amphibian world, where adaptation is everything🐸

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Reposted by Jorge Díaz

International Society of Developmental Biology @isdb.bsky.social · 26/01/2026

A new paper published in @jcb.org by postdoc Jorge Diaz from the Mayor lab at UCL shows that during collective migration, epithelial-like clusters generate traction force mainly through cryptic protrusions at the centre, while mesenchymal clusters do so at their periphery: doi.org/10.1083/jcb....

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