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Jon Mosser

@jonmosser.com
1K followers 757 following 290 posts

Pediatric infectious disease doc | global health researcher | modelling disease burden and intervention coverage from local to global scales | #vaccines, #VPDs, #NTDs, #malaria, #anemia, #hemoglobinopathies, #geospatial analysis | he/him | opinions my own

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Jon Mosser @jonmosser.com · 24/12/2025
(for real evidence of the safety of #vaccines, see this great website from the AAP)
healthychildren.org
Vaccine Safety: Examine the Evidence
Vaccines for kids are studied closely before the American Academy of Pediatrics recommends them. Safety evidence is gathered when a new vaccine is made and after it is authorized.
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Jon Mosser @jonmosser.com · 24/12/2025
This one might be my favorite. I feel like they might be missing one key reason why the smallpox vaccine isn't given anymore... No more smallpox! (Thanks to #vaccines!)
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Jon Mosser @jonmosser.com · 24/12/2025
And then, ironically, there was a "natural foods" store distributing these pamphlets inside the market just across the street. Did you know that polio is caused by DDT? And here I was thinking it was caused by a virus this whole time!
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Jon Mosser @jonmosser.com · 24/12/2025
Found a #vaccine mural downtown in #YorkPA while home for the holidays. I believe that these murals are based on drawings by Lewis Miller, Pennsylvania Dutch folk artist from the early 19th century.
An old mural of a man in a blue coat labeled "Dr. Kennedy" and a child in a yellow dress looking up at him. Text reads: "1799. Dr. Kennedy he waxanate the children with matter A remedy to cure the smallpox."
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PIDS @pidsociety.bsky.social · 05/12/2025
The Pediatric Infectious Diseases Society has issued the following statement on our deep concerns regarding the Advisory Committee on Immunization Practices December meeting and its impact on public health in the United States. pids.org/2025/12/05/p...
White text on red background with PIDS logo at bottom
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Washington State Department of Health @doh.wa.gov · 06/12/2025
WCHA disagrees with CDC’s Advisory Committee’s change to decades-long vaccine recommendation that has reduced pediatric hepatitis B infections by 99 percent. doh.wa.gov/newsroom/wes...
doh.wa.gov
West Coast Health Alliance, WA DOH, and Leading National Medical Organizations Continue to Recommend Hepatitis B Vaccination for Newborns
For immediate release: December 5, 2025 (25-145) Contact: DOH Communications
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Reposted by Jon Mosser
IDSA @idsainfo.bsky.social · 05/12/2025
The ACIP decision to discontinue the recommendation for a universal hepatitis B birth dose vaccine will cause harm. As the federal government continues to fail children's health, families can rely on our nation's physicians to continue to put children's health first.
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Jeremy Faust, MD @jeremyfaust.bsky.social · 06/12/2025
Friends, Yesterday and today, I watched many hours of the CDC’s meeting of the Advisory Committee on Immunization Practices (ACIP). It was painful. But we learned a lot. That bad news is that our kids are going to pay the price for RFK jr’s views. insidemedicine.substack.com/p/analysis-o...
insidemedicine.substack.com
Analysis of the latest ACIP meeting at the CDC: Vaccines—and rigorous science—are increasingly under attack.
A close look at how the CDC’s vaccine advisory committee under RFK Jr. again changed high-stakes recommendations without solid evidence.
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Jon Mosser @jonmosser.com · 05/12/2025
Blackburn clarifies that she is voting "yes for VFC to have coverage for what it needs to have coverage for", though it's unclear what that means nor whether that's what is actually being voted on. Final vote is 7 yes, 4 abstain.
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Jon Mosser @jonmosser.com · 05/12/2025
Multiple members including Hibblen, Pagano, Meissner abstain, noting that they don't actually know what they're voting on or what the ramifications would be of a vote either way.
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Jon Mosser @jonmosser.com · 05/12/2025
Meanwhile a totally different slide is shown indicating that the "purpose of the resolution is to update the Recommended Vaccination Schedule and Intervals section to reflect the updated ACIP recommendations about the use of Hepatitis B vaccine".
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Jon Mosser @jonmosser.com · 05/12/2025
Malone in midst of the vote, after several people have already voted: "what is at hand is the vote to adopt the ACIP recommendations into the Vaccines for Children program". Has to be corrected: "It is actually to approve the VFC resolution that was presented yesterday".
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Jon Mosser @jonmosser.com · 05/12/2025
The vote is to "approve the updated VFC resolution for prevention of hepatitis B".
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Jon Mosser @jonmosser.com · 05/12/2025
Malone calls for a bathroom break and has to be reminded that there's a third vote. There's now a third vote but several members, including Malone, do not appear to have any idea what the language is that they're voting on or what it would entail. Absolute scenes.
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Jon Mosser @jonmosser.com · 05/12/2025
No votes: Pollak, Meissner, Blackburn, Hibbeln. Stein abstains.
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Jon Mosser @jonmosser.com · 05/12/2025
#ACIP votes 6-4 to recommend that children could just get one dose of vaccine and then have post-vaccination serologic testing to see if more vaccines should be given. Multiple members remind the committee that there have been no studies or evidence to understand if this strategy would work.
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Jon Mosser @jonmosser.com · 05/12/2025
Now, after a bewildering discussion where members of the ACIP committee appear to not understand the difference between live viral vaccines like yellow fever and inactivated vaccines like hepatitis B, the committee votes on a recommendation to deviate from the established 3-dose primary series.
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Jon Mosser @jonmosser.com · 05/12/2025
Joseph Hibbeln: "This has a great potential to cause harm, and I simply hope that this committee will accept its responsiblity when this harm is caused -- and I vote no." Roger Malone: "Roger that."
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Jon Mosser @jonmosser.com · 05/12/2025
Dr. Cody Meissner, #pediatric #id doctor (the only one on #ACIP), reflecting on the committee's mandate to first do no harm: "We are doing harm by changing this wording, and I vote no."
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Jon Mosser @jonmosser.com · 05/12/2025
#ACIP votes to change the #hepatitisB #vaccine birth dose recommendation, ending the universal birth dose policies that have almost eliminated neonatal hepatitis B infection, cut pediatric infections by more than 95%, and prevented more than 6 million infections / a million hospitalizations.
cidrap.umn.edu
New review finds no evidence to support delaying universal hepatitis B birth-dose vaccination
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Jon Mosser @jonmosser.com · 05/12/2025
This article calls on global stakeholders to standardize definitions of timeliness and integrate timeliness into routine monitoring, so that all children can optimally benefit from the protection of vaccines.
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Jon Mosser @jonmosser.com · 05/12/2025
Timeliness is currently underexamined due to inconsistent definitions, poor data quality (like missing birth dates), and a lack of fine-scale estimates to track how timeliness varies within countries.
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Jon Mosser @jonmosser.com · 05/12/2025
Timeliness is important everywhere, but may be particularly important in places with relatively high coverage, to make sure that children are protected by vaccines before they are exposed to vaccine-preventable diseases.
 Comparison of improvements to coverage and improvements to timeliness. In countries with low immunisation coverage (A and B, solid line), improvements to coverage (A, dashed line) result in more child-months of protection during childhood (green shaded area) than improvements to timeliness (B, dashed line and green shaded area). In countries with high coverage (C and D), however, improvements to coverage (C) may result in fewer child-months of protection gained than improvements to timeliness (D).
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Jon Mosser @jonmosser.com · 05/12/2025
Current #immunization programs primarily track vaccination coverage (the percentage of children vaccinated), but this metric hides critical gaps like doses given too early or too late. Vaccination #timeliness -- receiving doses within the optimal, age-appropriate window -- is not as well tracked.
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Jon Mosser @jonmosser.com · 05/12/2025
Congratulations to Oghenebrume Wariri, MD, PhD for this new publication in Vaccine:X: "Vaccination timeliness is a key measure of immunisation system performance: A call to address priority research, policy and practice issues". Very thankful to have been part of this authorship team.
sciencedirect.com
Vaccination timeliness is a key measure of immunisation system performance: A call to address priority research, policy and practice issues
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Jon Mosser @jonmosser.com · 03/12/2025
Seattle has one of the biggest Somali populations in the country. I've had the privilege to work with loving, hardworking Somali families and patients + caring, brilliant Somali doctors during my time here. They belong here in our communities. Bigotry and xenophobia do not.
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Jon Mosser @jonmosser.com · 04/11/2025
Thanks to @thelancetinfdis.bsky.social for the opportunity to publish these updated estimates.
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Jon Mosser @jonmosser.com · 04/11/2025
Author Share link for the Lancet ID paper on the global, regional, and national burden of Chagas disease (free access for the next 50 days) authors.elsevier.com/a/1m2hA5E-Uo... Permanent link to the paper directly on the Lancet ID website: www.thelancet.com/journals/lan...
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Jon Mosser @jonmosser.com · 04/11/2025
Thank you to our multinational team of GBD 2023 Chagas Disease Collaborators, the RAISE Study, and our NTDs team at IHME for collaborating to produce this critical, updated analysis!
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Jon Mosser @jonmosser.com · 04/11/2025
To get better estimates, we need improved data quality, including adequate coding to prevent misclassification of Chagas deaths and better estimates of the true population at risk. Sustained funding for screening, treatment, and improved data collection is crucial to mitigate #Chagas disease burden.
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Jon Mosser @jonmosser.com · 04/11/2025
Prevalence also shifted to older age groups, peaking at 45–65 years in 2023. This reflects decreasing incidence in endemic locations. Health systems must prepare for chronic care needs as the burden of disease shifts to older populations.
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Jon Mosser @jonmosser.com · 04/11/2025
Cases in non-endemic locations increased 46.2%, primarily due to prevalence amongst people who have migrated from endemic countries. Improved awareness about #Chagas disease and systems to improve access to diagnosis & treatment for these individuals in non-endemic locations are needed.
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Jon Mosser @jonmosser.com · 04/11/2025
We estimated 10.5 million global prevalent cases in 2023. There has been major progress: age-standardised mortality dropped by 72.5% from 1990–2023. This success reflects strong vector control and socioeconomic development in endemic regions. #GlobalHealth #NTDs
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Jon Mosser @jonmosser.com · 04/11/2025
New GBD 2023 estimates of the burden of #Chagas disease, a #NTD caused by T. cruzi and transmitted by triatomine bugs, blood, or congenitally. The chronic phase, often decades after infection, causes severe heart failure, arrhythmias, and megaviscera. #GBD2023 #ChagasDisease #NTDs #IDSky
thelancet.com
Global, regional, and national burden of Chagas disease, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023
The GBD 2023 Chagas disease estimates are notably higher than previous GBD estimates, reflecting additional data and methodological improvements, and those published by the Pan American Health Organiz...
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Jon Mosser @jonmosser.com · 28/06/2025
Out now in @plos NTDs - overlap between #LF prevalence and #malaria ITN access / use. Congrats to Joanna Whisnant and the authorship team. This has been a long time coming and great to see it out! #NTDs #episky #malaria #lymphaticfilariasis
doi.org
Examining the overlap in lymphatic filariasis prevalence and malaria insecticide-treated net access-use in endemic Africa
Author summary Lymphatic filariasis is a vector-borne disease that can cause significant disability. There is evidence that insecticide-treated nets used by malaria programs can contribute to lymphati...
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Jon Mosser @jonmosser.com · 25/06/2025
#pedsky #episky #idsky #pedsidsky
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Jon Mosser @jonmosser.com · 25/06/2025
I had the chance to speak with @npr.org before this announcement, on this critical moment for #vaccination. "The world is going to have to pick a trajectory," [Mosser] says. "Are we going to turn our backs on one of the most remarkable public health achievements that the world has ever seen?"
npr.org
The good news (154 million deaths avoided) and bad news about childhood vaccines
A new study points out success stories — and potential obstacles — to bringing vaccines to the world's children.
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Jon Mosser @jonmosser.com · 25/06/2025
“In the face of demonstration that vaccines are the single most lifesaving technology for children, over half a century, he is asserting a position that the U.S. will not support vaccination. This is utterly disastrous for children around the world and for public health.” -- @agawande.bsky.social
nytimes.com
Kennedy Withdraws U.S. Funding Pledge to International Vaccine Agency
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Jon Mosser @jonmosser.com · 25/06/2025
Bill Moss of @ivac-hopkins.bsky.social on the challenges to come: "...the study’s analysis took place prior to the shifts in U.S. federal funding... “The situation is even more challenging, I think, in the coming years than is even outlined in this analysis,” Moss told STAT."
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Jon Mosser @jonmosser.com · 25/06/2025
"Whatever progress we’ve made could be reversed if we don’t maintain and build on our successful #immunization efforts to date.” - Prof. Art Reingold, @berkeleypublichlth.bsky.social. Read more @statnews.com
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Jon Mosser @jonmosser.com · 25/06/2025
"Falling global #vaccine coverage, an increase in the numbers of children receiving no vaccines, and delays in vaccination mean that more children will be hospitalised, permanently damaged and die from fully preventable diseases if the trend is not reversed." - Prof. Andrew Pollard
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Jon Mosser @jonmosser.com · 25/06/2025
The evidence couldn't be more clear: * #Vaccines are safe. * #Vaccines are effective. * #Vaccines save lives. This is the moment for a renewed global commitment to immunization at all levels.
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Jon Mosser @jonmosser.com · 25/06/2025
We have a choice: do we turn our backs on the most successful public health intervention that the world has ever known? Or do we redouble our efforts to ensure that everyone, everywhere can benefit from the protection of lifesaving #vaccines? /🧵
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Jon Mosser @jonmosser.com · 25/06/2025
In the decades to come, we need strong global leadership and support from governments and other programs. We need to ensure that national immunization programs have the resources they need to tailor vaccination programs to the needs of their communities.
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Jon Mosser @jonmosser.com · 25/06/2025
The evidence couldn't be more clear: * #Vaccines are safe. * #Vaccines are effective. * #Vaccines save lives. This is the moment for a renewed global commitment to immunization at all levels.
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Jon Mosser @jonmosser.com · 25/06/2025
As we move into the second half of this decade, we're at a pivotal moment - coming out of the COVID pandemic, partially but not fully recovered from its impact, and on the heels of more than a decade of slowed progress in many countries. We're at a crossroads.
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Jon Mosser @jonmosser.com · 25/06/2025
And USAID has had a key role in monitoring vaccine coverage, particularly in LMICs, through the Demographics and Health Surveys. Just over half of all of our survey data sources in this study came from the DHS program. This data is crucial to monitor immunization and many other health metrics.
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Jon Mosser @jonmosser.com · 25/06/2025
@Gavi has played a major role in supporting many countries in rolling out and scaling up new vaccines and enhancing delivery for more established vaccines, while they work towards more sustainable domestic funding approaches.
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Jon Mosser @jonmosser.com · 25/06/2025
WHO plays a key role in providing guidance, too - for instance, in developing strategies that have been crucial in mitigating the effects of the COVID-19 pandemic on essential health services like immunization.
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Jon Mosser @jonmosser.com · 25/06/2025
In our manuscript, for instance, we rely heavily on data collected by @who.int and @unicef.org, as well as the contextual information that comes from their expertise and close connections with countries.
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