Sign in

Jones Comp Neuro Lab

@jonescompneurolab.bsky.social
45 followers 8 following 13 posts

Computational neuroscience lab at Brown University developing biophysically principled models of neural circuits that bridge EEG measures of brain function to cellular and network level dynamics. sites.brown.edu/stephanie-r-jones-l…

PostsRepliesMedia
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 18/05/2026
We are still accepting responses for this survey! forms.gle/jjrdr97nPpHB... If you have heard of HNN before, attended a workshop, or used it for a project, please tell us about your experience! Our lab is working hard to provide better support for users interested in HNN
docs.google.com
HNN Dissemination Feedback
The goal of this survey is to gather information on current community use of the Human Neocortical Neurosolver (HNN) software. This survey is intended for users who have heard of HNN, attended a works...
000
Reposted by Jones Comp Neuro Lab
Nicholas Tolley @ntolley.bsky.social · 05/05/2026
Super glad to have our team's work on clinical applications of neural simulations highlighted in this article! Trying to bring academic work to the real-world has been a great experience and I'm quite excited to continue these efforts with @dvwz.bsky.social and @jonescompneurolab.bsky.social
0102
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 11/05/2026
Jacob Tajchman, a Master's student in the lab, recently successfully defended his thesis titled "Computational Modeling of Neural Cell-Type Targeting with Transcranial Magnetic Stimulation" 🥳🎉 He will continue his research at Brown next fall as a PhD student in Neuroscience. Congratulations Jacob!
010
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 27/04/2026
Five posters from the Jones lab at SOBP! 🧠 💭 Come chat with us about biophysical mechanisms, deep learning approaches to EEG analysis, and treatment response prediction!
022
Reposted by Jones Comp Neuro Lab
Nicholas Tolley @ntolley.bsky.social · 17/04/2026
Happy to share a new preprint from the @hnnsolver.bsky.social team!🧠💻🎉 "Uncovering putative neural mechanisms of neurotherapeutic impacts on EEG using the Human Neocortical Neurosolver" 📝 www.biorxiv.org/content/10.6...
Biophysical modeling to develop and test mechanistic hypotheses underlying pharmacological EEG biomarkers.

Top: Modeling EEG biomarkers begins with picking a specific brain signal that is reliably different between patient populations. An example of a hypothetical EEG biomarker is an auditory event related potential (ERP) that is suppressed in post-treatment (red) relative to pre-treatment (blue). Middle: Biophysical modeling allows for testing mechanistic hypotheses that explain how EEG biomarkers emerge and change with drugs. Hypotheses about which drug mechanisms lead to distinct brain activity patterns must be constructed, and corresponding model parameters identified. Bottom: The default HNN model is used as a starting point to test hypotheses by either manually altering the values of the chosen model parameters, or using automated optimization and inference algorithms. Differences in parameter values pre-to post-treatment correspond to model-based predictions.
12311
Reposted by Jones Comp Neuro Lab
Nicholas Tolley @ntolley.bsky.social · 18/03/2026
Happy to share a new preprint from my PhD thesis! “A novel framework for expanding RNNs with biophysical detail to solve cognitive tasks” 🧠💻 📝 www.biorxiv.org/content/10.6... @jonescompneurolab.bsky.social
Multipanel figure illustrating the key components of the paper: 1) biophysical reservoir computing where a network of biophysically detailed excitatory and inhibitory neurons are randomly connected, receive a brief input, and produce a sustained spiking pattern in response, 2) an illustration of the task the biophysical reservoir computer is trained on: a simplified working memory task where the network must produce distinct fixed point attractors in response to different inputs.
15618
Reposted by Jones Comp Neuro Lab
Carney Institute for Brain Science @carneyinstitute.bsky.social · 23/01/2026
Congrats to @jonescompneurolab.bsky.social, @desrocherslab.bsky.social and Leenoy Meshulam for being recognized by Brown on their recent awards from the National Institute of Neurological Disorders and Stroke, NYU and the Allen Institute! Check it out: www.brown.edu/news/2026-01-15/faculty-awards
brown.edu
Faculty at Brown earn prominent awards, distinctions in Fall 2025
Over the fall semester, prestigious national and international organizations recognized Brown faculty for their research, service, scholarship and leadership.
061
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 20/02/2026
Our amazing undergrad RA Phillip recently tabled at a STEM Night event at Nayatt Elementary School in Barrington. Here are some photos of Phillip talking about electricity, EEG, and research at Brown to the students and family!
020
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 20/02/2026
Our research on biomarker for Alzheimer’s disease progression has been gaining traction on social media! Check out the video by Hashem Al-Ghaili: www.linkedin.com/posts/hashem... and the reply by Danylyna Shpakivska, the author of the highlighted paper: www.linkedin.com/feed/update/...
linkedin.com
#alzheimersdisease #neuroscience #computationalneuroscience #meg #neuraldynamics #biophysicalmodeling | Danylyna Shpakivska
Following the recent video by Hashem Al-Ghaili highlighting our work on beta events in MCI and Alzheimer’s disease progression — here’s where we are now. The video discusses our recent paper in Imag...
010
Reposted by Jones Comp Neuro Lab
Human Neocortical Neurosolver @hnnsolver.bsky.social · 14/11/2025
📣 Help us improve HNN features and educational resources for you! 📣 If you have heard about HNN, interacted with the software, or used it for a research project, we'd love to hear from you in this <5 min survey! forms.gle/LB29PXMbEQak...
forms.gle
HNN Dissemination Feedback
This short survey aims to gather information on current community usage of the Human Neocortical Neurosolver (HNN) software. Please fill out this survey if you have heard of HNN, attended a workshop...
021
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 14/11/2025
The Jones comp neuro lab is at #SfN25! Come check out our talks and posters to learn about our latest & greatest Science with HNN! All poster presentation times & locations can be found at jonescompneurolab.github.io/textbook/res...
jonescompneurolab.github.io
HNN Textbook
184
Reposted by Jones Comp Neuro Lab
Human Neocortical Neurosolver @hnnsolver.bsky.social · 30/09/2025
HNN was recently featured on the @carneyinstitute.bsky.social website and newsletter! Check out this article for the unique history and applications of HNN: carney.brown.edu/close-human-...
carney.brown.edu
Up Close: The Human Neocortical Neurosolver
A transformative tool decodes electrical activity in the brain to reveal the behavior of neurons, opening new doors in research.
021
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 29/08/2025
A patent filed by the lab is up for a Brown Innovation of the Year award! “Personalized Transcranial Magnetic Stimulation (TMS) Delivery Protocols Based on Computational Modeling of the Electromagnetic TMS-evoked Response” was filed by Drs. Sliva and Jones. View and vote here tinyurl.com/nx37789m
tinyurl.com
Microsoft Forms
021
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 18/08/2025
Catching up on good news — Ryan Thorpe defended his thesis back in August 2024! He has since started a postdoc at University of Colorado. Congratulations, Dr. Thorpe 🎉🍾
020
Jones Comp Neuro Lab @jonescompneurolab.bsky.social · 07/08/2025
Our PhD student @ntolley.bsky.social successfully defended his thesis, "Bridging biophysics and emergent dynamics through deep learning assisted modeling of the neocortex", on July 9th, 2025. Congratulations Dr. Tolley!!! 🎉🎉
061