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Jamie Walker, MD, PhD

@jmewalker.bsky.social
645 followers 334 following 11 posts

Neuropathologist at Mount Sinai NYC | research interests: healthy aging, #resistance and #resilience against #Alzheimer's pathology, spatial proteomics, hippocampi | other interests: tennis, nature, hiking, rock climbing |

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Reposted by Jamie Walker, MD, PhD
Dave Weisman @dweisman.bsky.social · 31/12/2024
Patient can’t look up or down. What’s going on?
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Jamie Walker, MD, PhD @jmewalker.bsky.social · 31/12/2024
AD, PART and CTE share the same 3R/4R-tau+ NFTs, but in a different distribution … what about their proteomes? Excited to share our spatial proteomics study comparing #Alzheimers, #PART and #CTE hippocampi doi.org/10.1002/alz.... #neuropath #neuroscience #neurology #proteomics
doi.org
Spatial proteomic differences in chronic traumatic encephalopathy, Alzheimer's disease, and primary age‐related tauopathy hippocampi
INTRODUCTION Alzheimer's disease (AD), primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE) all feature hyperphosphorylated tau (p-tau)–immunoreactive neurofibrillary deg...
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Jamie Walker, MD, PhD @jmewalker.bsky.social · 17/12/2024
This is a spinal cord anterior horn motor neuron … do you see what 👁️see? #neuropath #neuroskyence
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Reposted by Jamie Walker, MD, PhD
Klara Gawor @gawor-neuro.bsky.social · 14/12/2024
Brains of Alzheimer's patients—but look at the other aggregated proteins! We explore how two distinct variants of αSynuclein co-pathology contribute to hippocampal degeneration. Check out our new article in @braincomms.bsky.social: academic.oup.com/braincomms/a... 🧠🧪
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Jamie Walker, MD, PhD @jmewalker.bsky.social · 13/12/2024
Here’s a pineal gland, named after the pine cone! Did you know Descartes thought the pineal was the seat of the soul? www.neurology.org/doi/10.1212/... The brain is cut in the axial plane here. What other structures can you identify? Happy Holidays! #neuroskyence #neuropath #neurology #neuroanatomy
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Reposted by Jamie Walker, MD, PhD
Rita Strack @ritastrack.bsky.social · 06/12/2024
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
nature.com
Method of the Year 2024: spatial proteomics - Nature Methods
Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.
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Jamie Walker, MD, PhD @jmewalker.bsky.social · 22/11/2024
Got some new cookie cutters … the heart and the coronal section! Can you guess any of the diagnoses? #neuropath #neuroscience #neuroskyence
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Reposted by Jamie Walker, MD, PhD
Matthias Nau @matthiasnau.bsky.social · 17/11/2024
Fantastic explanation of the anatomy of the human #Hippocampus! Great video and visualizations!👌 #neuroscience #PsychSciSky vimeo.com/323365182
vimeo.com
Morphology of Memory: The Anatomy of the Human Hippocampus
The hippocampus is a part of the brain known to be critical for learning and memory. It is made up of many interconnected regions with distinct characteristics.…
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Jamie Walker, MD, PhD @jmewalker.bsky.social · 14/11/2024
Check out this cool #hippocampus with what appears to be hippocampal sclerosis. #neuropath
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