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Jérôme Hénin

@jerome-henin.eurosky.social
199 followers 72 following 15 posts

CNRS Research Director - Goal: learn more from molecular simulations. Laboratoire de Biochimie Théorique (LBT) Institut de Biologie Physico-Chimique (IBPC) Paris see also mstdn.science/@jerome_henin

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Jérôme Hénin @jerome-henin.eurosky.social · 15/10/2026
Very glad to introduce LAO+, the next step in alchemical free energy calculation for challenging cases - from the collaboration with @jppiquem.bsky.social and coworkers.
arxiv.org
LAO+: Focused, Multi-Replica Accelerated Orthogonal Sampling for Robust Binding Free Energy Predictions
We introduce Lambda-ABF-OPES+ ($\text{LAO+}$), a multi-replica framework for absolute binding free energy (ABFE) calculations that accelerates both the alchemical transformation and the slow ``orthogo...
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Jérôme Hénin @jerome-henin.eurosky.social · 15/10/2026
New open postdoc position in Paris, joint between my group and Guillaume Stirnemann's group at ENS. Goal: computational study of GPCR sensitivity to membrane lateral pressure, in close collaboration with excellent experimental biochemists and biophysicists. Duration: 2 years.
lbt.cnrs.fr
Postdoctoral Position: Molecular Dynamics Simulations of GPCR Mechanosensitivity - Laboratoire de Biochimie Théorique
Duration: 2 years Location: LBT/IBPC and ENS, Paris, France Supervisors: Jérôme Hénin (LBT, IBPC) and Guillaume Stirnemann (ENS) Project Context: […]
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Jake Grumbach @jakemgrumbach.bsky.social · 09/10/2026
New working paper: the Norwegian wealth tax was a huge success. The "exodus" of wealthy people never happened (less than 100 individuals left). Tax revenue increased by 71.5%. No changes in business activity or investment. www.nber.org/papers/w35854
Taxing Entrepreneurial Wealth: Evidence from
Norway, 2021-2025
Marius A. K. Ring
WORKING PAPER 35854|
DOl 10.3386/w35854
ISSUE DATE October 2026
Whether imposing higher taxes on business owners adversely affects business activity by constraining investment and inducing capitalist flight is a central question in the ongoing debate on how to tax the ultra wealthy. To shed new light, I exploit a series of related Norwegian reforms during 2021-2024 that increased dividend tax rates, removed migration-related capital gains tax loopholes, and nearly doubled the effective marginal tax rate on business wealth. These reforms spurred international debate and, allegedly, an "exodus" of Norwegian billionaires (Financial Times,
2023). While I document clear effects on migration, these responses are concentrated among the top 0.1% of the wealth distribution and mostly confined to 2022 and 2023. My results indicate that at most 100 individuals left due to the reforms. I find no evidence of significant outmigration or reduced inflows of startup founders or inventors. I estimate that absent any outmigration, wealth tax revenues would have increased by 75% from 2021 to 2024. Reform-driven outmigration lowers the revenue gain to 71.5%. My findings further show that outmigrating owners' firms remain economically active and do not reduce investment. In a broader set of analyses, I examine whether business outcomes are affected, regardless of whether owners outmigrate, since firms may reduce investment both due to liquidity constraints or distortions to owners' savings decisions. I compare firms owned by Norwegian individuals subject to the wealth tax with firms owned by foreigners and other tax-exempt entities. By merging historical ownership data from Orbis with the Norwegian shareholder register, I perform these analyses on both Norwegian and foreign-domiciled firms.
Across settings, I find no evidence that Norwegian-owned firms pay out more dividends or invest less after the reforms,…
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Dr. Hab Sophie Sacquin-Mora @sacquin-mo.eurosky.social · 12/10/2026
In 2026, the LBTDays will take you on a journey across the cellular world using the computational microscope ! The meeting's website is now online. Due to space limitation in the IBPC library, registration is mandatory : lbtdays2026.sciencesconf.org
lbtdays2026.sciencesconf.org
LBT days 2026 - Sciencesconf.org
Sciencesconf.org
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Stephen Curry @scurry.bsky.social · 28/09/2026
New mapping app: Google War Crimes
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FX Coudert @nanoporous.net · 17/09/2026
What peer-reviewed science looks like at MDPI:
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Jérôme Hénin @jerome-henin.eurosky.social · 08/09/2026
First meme about magnesium phosphate has dropped
Molecular rendering of a phosphate-magnesium ion pair. Caption: Name a more ionic duo... I'll wait.
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Jérôme Hénin @jerome-henin.eurosky.social · 18/07/2026
Brilliant! Ideally, it would be even better to avoid the biological metaphor, a proposed by @emilymbender.bsky.social and @nannainie.bsky.social buttondown.com/maiht3k/arch... ...but I don't have a specific idea to offer for that. The bottom feeder image is quite striking and hard to match.
buttondown.com
How to talk about "AI" without adding to the anthropomorphization
Emily M. Bender and Nanna Inie In our op-ed for Tech Policy Press ("We Need to Talk About How We Talk About 'AI'"), we made the case against the...
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Jérôme Hénin @jerome-henin.eurosky.social · 10/12/2025
LLM users (like me) should strive to obtain this reply from them at least once a day, as a reminder.
You are absolutely right. I am hallucinating.
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Ewen Lescop @ewenlescop.bsky.social · 16/07/2025
Happy to share our recent work bridging #highpressureNMR and #MDsimulation to highlight an allosteric pathway between lipid bulk properties and conformational changes at the core of a membrane protein. doi.org/10.1016/j.bp... @icsnlab.bsky.social @cpcv.bsky.social @cnrs.fr #UnderPressure
doi.org
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Ewen Lescop @ewenlescop.bsky.social · 16/07/2025
Wonderful collaboration with L. Catoire (BPM-IBPC), @jerome-henin.bsky.social (LBT-IBPC) and G. Stirnemann (CPCV). Congrats to Clarisse Fourel and @yannagautier.bsky.social‬ for their excellent work and first paper and to F. Giraud and A. Pozza for their strong expertise ! #happyPhDsupervisor
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Jérôme Hénin @jerome-henin.eurosky.social · 09/07/2025
En 2025, on ne peut plus être climatosceptique - mais on peut être climatonégationniste.
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Jérôme Hénin @jerome-henin.eurosky.social · 09/07/2025
Et si cette administration est une préfecture qui devait renouveler ton titre de séjour, tu te retrouves "en situation irrégulière".
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Jérôme Hénin @jerome-henin.eurosky.social · 27/05/2025
Traveling to the UK... - Are you a member of a terrorist group? That's an easy one. - Have you ever been *suspected* of *expressing* extremist *views*? By whom? How would I know? What kind of views? My views about food can be intense - some might call them extreme. Do I qualify?
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Tom Fletcher @tomfletcherun.bsky.social · 14/05/2025
So, for those killed and those whose voices are silenced: what more evidence do you need? Will you act now – decisively – to prevent genocide in Gaza and to ensure respect for international humanitarian law? This Council must prevail. Demand this ends.
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Jérôme Hénin @jerome-henin.eurosky.social · 14/04/2025
Six women programmed ENIAC, in a foundational contribution to computing and programming - and then they were nearly forgotten. Betty Holberton, Jean Bartik, Kay McNulty, Ruth Teitelbaum, Marlyn Meltzer, and Frances Spence. threadreaderapp.com/thread/19096...
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Eric Schares @eschares.bsky.social · 18/11/2024
🚨 Preprint! We combine our recent open dataset of #APC prices with the article counts per journal-year from #OpenAlex to estimate how much the academic community has paid in APCs over the last 5 years. A. $8.349 billion ($8.968 B in 2023 USD) $2.5B in 2023 alone. arxiv.org/abs/2407.16551 #metasci
arxiv.org
Estimating global article processing charges paid to six publishers for open access between 2019 and 2023
This study presents estimates of the global expenditure on article processing charges (APCs) paid to six publishers for open access between 2019 and 2023. APCs are fees charged for publishing in some ...
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Jérôme Hénin @jerome-henin.eurosky.social · 26/03/2025
In other words: an order parameter is not a reaction coordinate!
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Élise Duboué-Dijon @elisedd.bsky.social · 26/03/2025
Job alert ! I am looking for a postdoc to work on "computational investigation of ion-effects in ribozyme catalysis" to work with me in Paris (France). 1-year contract funded by @agencerecherche.bsky.social, with possible 2nd year in collab. with P. Jungwirth @iocbprague.bsky.social #compchem #RNA
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Jérôme Hénin @jerome-henin.eurosky.social · 05/03/2025
Hadrien Vroylandt is starting his group at the University of Caen and hiring grad students and postdocs in physical and computer sciences to work on AI for science: vroylandt.users.greyc.fr
vroylandt.users.greyc.fr
Hadrien Vroylandt
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Jon Cooper @joncooper-us.bsky.social · 28/02/2025
Pass it on. #StandWithUkraine
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Jérôme Hénin @jerome-henin.eurosky.social · 24/12/2024
Two conclusions I draw from this: 1) try linear ML first, and if it does the job, stick with it. 2) whenever using ML, keep in mind exactly what is being optimized (and if that's too complicated to keep in mind, maybe stay away from that method). simplystatistics.org/posts/2024-1...
simplystatistics.org
Simply Statistics: Biologists, stop putting UMAP plots in your papers
UMAP is a powerful tool for exploratory data analysis, but without a clear understanding of how it works, it can easily lead to confusion and misinterpretation.
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Jérôme Hénin @jerome-henin.eurosky.social · 12/12/2024
🚨 Announcing the 1st Colvars Dashboard mini-workshop 🚨 (an interactive VMD tool to explore MD data in collective variable space) Aims: discuss use cases, tips, feedback, and ideas for further development. Online event on Jan 17 2025. Details and registration: forms.gle/yTq3C8kHER8i...
forms.gle
Colvars Dashboard mini-workshop
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Dr. Hab Sophie Sacquin-Mora @sacquin-mo.eurosky.social · 04/12/2024
Le LBT se cherche un·e administrateurice systèmes et réseaux. Pour le moment le poste est ouvert en NOEMI (mobilité), donc si vous êtes déjà en poste et souhaitez nous rejoindre, c'est par ici ! mobiliteinterne.cnrs.fr/ords/afip/ow...
media.tenor.com
a penguin wearing blue overalls and a red bandana says we need you
Alt: a penguin wearing blue overalls and a red bandana says we need you
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Élise Duboué-Dijon @elisedd.bsky.social · 24/11/2024
Tomorrow are starting our #LBTdays2024 on challenges in biomolecular simulations, that we organize in Paris at #IBPC. We have a fantastic lineup of speakers, can't wait for it to start ! #compchem @cnrs.bsky.social @cecamevents.bsky.social
Program with list of speakers and titles
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Élise Duboué-Dijon @elisedd.bsky.social · 24/11/2024
#LBTdays2024 fully updated program, with all titles. See you there tomorrow !
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Peer Community In @peercommunityin.bsky.social · 22/11/2024
📣 Save the date for the 9th PCI webinar: 5/12/24 at 4 pm CET: How much is too much? Estimating APCs and questioning sustainability by Leigh-Ann Butler (Scholarly Communication Librarian, University of Ottawa). Mandatory registration:
buff.ly
Welcome! You are invited to join a meeting: PCI webinar series - 5th December 2024 - 4pm CET [to 5.15 pm] (Paris Time) - How much is too much? Estimating APCs and questioning sustainability. After registering, you will receive a confirmation email about joining the meeting.
Speaker: Leigh-Ann Butler Title: How much is too much? Estimating APCs and questioning sustainability Abstract: First, the serials crisis strained academic budgets; now it’s article processing…
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Jérôme Hénin @jerome-henin.eurosky.social · 15/11/2024
A foundational simulation work, 34 years after the first molecular mechanics paper - 1930 - no computers, but analog models with literal balls and springs. Kettering et al. predicted the structure of molecules by matching the models' vibration patterns with Raman spectra. doi.org/10.1103/Phys...
Black-and-white photographs of five different, analog balls-and-springs models of the benzene molecule
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Jérôme Hénin @jerome-henin.eurosky.social · 15/11/2024
New reference paper for the Colvars library is out! Collective variables at your fingertips in software from Gromacs to VMD. pubs.acs.org/doi/abs/10.1...
pubs.acs.org
Expanded Functionality and Portability for the Colvars Library
Colvars is an open-source C++ library that provides a modular toolkit for collective-variable-based molecular simulations. It allows practitioners to easily create and implement descriptors that best ...
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