iiinova — where your digital self keeps evolving

Jeremy Brown @jeremypb.bsky.social · 08/06/2026

New article in Annals of Internal Medicine! In our target trial emulation of 3,572 pregnancies there were not large differences in the risk of non-live birth, major malformations, and abnormal fetal growth with continuation of GLP-1 receptor agonists into early pregnancy vs. non-continuation.

acpjournals.org

Continuing Glucagon-Like Peptide-1 Receptor Agonists Into the First Trimester of Pregnancy and Pregnancy Outcomes: A Target Trial Emulation Study Using Claims Information: Annals of Internal Medicine:...

Background: Glucagon-like peptide-1 receptor agonist (GLP-1RA) use has increased among women of reproductive age, but limited data exist on safety in pregnancy. Objective: To estimate the risk for non...

030