iiinova — where your digital self keeps evolving

Reposted by James DeGregori

Rob Noble @robjohnnoble.bsky.social · 04/09/2026

Nice to see this properly published: a framework for designing therapies targeting tumor-level dynamics rather than cell number. Led by Fred Thomas with contributions from @amdujon.bsky.social, @jdegregori.bsky.social, me, and many others apparently not on Bluesky. www.nature.com/articles/s41...

nature.com

When effective anticancer therapies are, in fact, destabilizing the tumor’s Group Phenotypic Composition - npj Precision Oncology

npj Precision Oncology - When effective anticancer therapies are, in fact, destabilizing the tumor’s Group Phenotypic Composition

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Reposted by James DeGregori

CU Anschutz Cancer Center @cucancercenter.bsky.social · 01/05/2026

#SkinCancerAwarenessMonth: Interim Director @jdegregori.bsky.social, shares his experience of having two instances of squamous cell carcinoma and how you can prevent skin cancer. Learn more about skin cancer: bit.ly/467Yv97

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Reposted by James DeGregori

edwardevansjr.bsky.social @edwardevansjr.bsky.social · 02/07/2026

So many people to thank for huge efforts: Ferriol Calvet in Nuria Bigas Lopez lab in Barcelona, Fabio Marongiu in Sardinia, Emilia Lim in Vancouver, @charlesswanton.bsky.social, Faiz Jabbar, my primary research mentor @jdegregori.bsky.social , and so many more. It was a huge collaborative efort.

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Reposted by James DeGregori

Rob Noble @robjohnnoble.bsky.social · 23/09/2025

Join @cmaley.bsky.social, @lucielaplane.bsky.social, Joel Brown and Benjamin Spada for a live EvoChat discussion about "How we define cancer matters", hosted by the International Society for Evolution, Ecology and Cancer (ISEEC). Oct 1st at 8am PST, 11am EST, 5pm CEST ucsb.zoom.us/j/8313111375...

Abstract: Current definitions of cancer describe what cancer does but not what it is. Furthermore, they derive largely from human cases and may not apply to other multicellular organisms, especially those lacking a basal membrane. Comparative oncology, however, has shown that cancer occurs across a broad diversity of organisms. What definition should be adopted when framing cancer in a comparative and evolutionary perspective? And can an evolution-based definition be applied in clinical oncology? We will show that a universal definition of cancer not only helps provide a basis for progress in comparative oncology, but can also help to explain the diversity of cancer phenomena within humans.

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Reposted by James DeGregori

Aguirre-Ghiso Lab @jaguirreghisolab.bsky.social · 08/06/2025

Important findings from the @soledadsosalab.bsky.social at the @cdi-einstein.bsky.social at Montefiore Einstein Comprehensive Cancer Center on the mechanisms of dormant cutaneous melanoma awakening via midkine dependent signaling. Congrats on this story! www.biorxiv.org/content/10.1...

biorxiv.org

Midkine inhibits dormancy of disseminated melanoma cells

A significant factor in cancer-related mortality in melanoma is the appearance of intrinsically aggressive distal metastases. This recurrence frequently results from the awakening of dormant dissemina...

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James DeGregori @jdegregori.bsky.social · 22/04/2025

Check out the symposium on “Cancer in an evolutionary framework: across species and within individuals” at the ESEB conference in Barcelona this August. Flyer: www.canva.com/design/DAGjV... Abstract submission closes this Friday: eseb2025.com/call-for-abs...

eseb2025.com

Call for Abstracts – ESEB 2025. Congress of the European Society for Evolutionary Biology. Barcelona. Spain

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James DeGregori @jdegregori.bsky.social · 23/01/2025

Check out the editorial from Montano, Seidl and me announcing a new virtual issue spanning multiple Wiley journals on Aging and Cancer. Reach out if you are interested in contributing! onlinelibrary.wiley.com/doi/10.1111/...

onlinelibrary.wiley.com

Aging and Cancer—Inextricably Linked Across the Lifespan

Aging (as old man wind) alters the trajectory of cancer (dangerous seas) through changes in the immune system and metabolism (among many others), leading to altered cancer epidemiology, pathogenesis,...

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James DeGregori @jdegregori.bsky.social · 27/11/2024

Check out the conference in Hainan China on Aging and Cancer. It's Dec 13-14 (starting 12th for those in the West), there is a virtual option (yea, you don't need to fly to China), a great line up of speakers, and it's FREE. www.icacconference.com/2024/

icacconference.com

衰老与肿瘤国际研究中心

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