Molecular Psychiatry - A study of gene expression in the living human brain

Zaman, Yang and Huang et al. demonstrate MDK’s suppressive effect on amyloid-β and its impact on amyloid burden and microglial activation in Alzheimer disease mice, highlighting its protective role in...

The advancements of proteomics technologies are shaping Alzheimer's disease (AD) research, revealing new molecular insights and improving biomarker discovery. Here, we summarize major AD proteomics st...

This study maps proteomic changes in Alzheimer’s mouse models, identifying shared pathways with humans, amyloid-driven protein turnover, and proteome-transcriptome differences, offering insights into ...