iiinova — where your digital self keeps evolving

Reposted by Jan Böhning

Tanmay Bharat @tbharat-lab.bsky.social · 30/09/2026

Diverse S-layer anchoring mechanisms create an epiplasmic space in prokaryotic cell envelopes. Our review with @bupbuse.bsky.social and @vikramalva.bsky.social discussing a cellular compartment created by the S-layer out in Current Opinion in Microbiology. www.sciencedirect.com/science/arti...

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Reposted by Jan Böhning

Tanmay Bharat @tbharat-lab.bsky.social · 23/08/2026

Molecular architecture of colossal surface layers from hyperthermophilic archaea Led by @idocaspy.bsky.social (Ido) In collaboration with @mkrupovic.bsky.social and @vikramalva.bsky.social labs doi.org/10.64898/202...

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Reposted by Jan Böhning

Tanmay Bharat @tbharat-lab.bsky.social · 15/07/2026

Structural basis of biofilm formation mediated by the Pseudomonas aeruginosa fibrillar adhesin CdrA led by @olivia--smith.bsky.social Collaboration with @alexbateman1.bsky.social , Andres Floto and @geiselbiofilm.bsky.social labs

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Reposted by Jan Böhning

Tanmay Bharat @tbharat-lab.bsky.social · 25/05/2026

Sub-cellular chemical mapping using correlated cryogenic electron and mass spectrometry imaging online @natmethods.nature.com, led by Hannah Ochner, collaboration with @catfranco.bsky.social and @kiranrpatil.bsky.social labs doi.org/10.1038/s415...

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Reposted by Jan Böhning

Sjors Scheres @sjorsscheres.bsky.social · 16/02/2026

Please spread the word: the Structural Studies Division @mrclmb.bsky.social is looking for a new tenure-track, independent group leader with an exciting plan in any area of Structural (Molecular & Cell) biology, in discovery biology and/or methods development. 🥳 mrc.tal.net/vx/mobile-0/...

mrc.tal.net

Research Group Leader Tenure Track - Structural Studies - LMB 2775 - Medical Research Council

Location: Cambridge. Vacancy: Research Group Leader Tenure Track - Structural Studies - LMB 2775. Closing Date: 16/03/2026, 23:55

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Reposted by Jan Böhning

Tanmay Bharat @tbharat-lab.bsky.social · 31/08/2025

Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social www.biorxiv.org/cgi/content/... @mrclmb.bsky.social @wellcometrust.bsky.social

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Reposted by Jan Böhning

Tanmay Bharat @tbharat-lab.bsky.social · 29/07/2025

Targeted disruption of phage liquid crystalline droplets abolishes antibiotic tolerance of bacterial biofilms led by @abultarafder.bsky.social Great collaboration with @pearce-maths.bsky.social and @geiselbiofilm.bsky.social www.biorxiv.org/cgi/content/...

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Reposted by Jan Böhning

Adam Fountain @adamfountain.bsky.social · 26/06/2025

Bedaquiline resistance driven by the MmpS5L5 efflux pump is threatening the drug regimens used to treat MDR-TB. In our new preprint, we used structural and genetic approaches to better understand how MmpS5L5 effluxes bedaquiline and how future resistance may evolve. 🧵🔽 #TBsky #MicroSky #TB

biorxiv.org

Structural and functional analysis of the Mycobacterium tuberculosis MmpS5L5 efflux pump presages a pathway to increased bedaquiline resistance

Bedaquiline, an antitubercular drug that targets ATP-synthase, is a key component of a new oral drug regimen that has revolutionized the treatment of multi drug resistant tuberculosis. Clinical bedaqu...

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