Jake Matthews @jakemat91.bsky.social · 20/07/2025linktr.ee/jakemat91linktr.eejakemat91 | Twitter, Instagram | LinktreeDoctor Academic Athlete Dad 000
Jake Matthews @jakemat91.bsky.social · 20/07/2025If a paper is posted on the Net, but nobody reads it. Does it make an impact? #TeamGP #Academia #Publishing www.linkedin.com/posts/jake-m...linkedin.comIf a paper is posted on the Net, but nobody reads it. | Jake MatthewsIf a paper is posted on the Net, but nobody reads it. Does it make an impact? Lots of junior clinicians and academics ask about how to disseminate their work or how to choose what projects to do to ... 120
Reposted by Jake MatthewsOliver O’Sullivan @ollieosul.bsky.social · 06/06/2025Medical Leadership Development for Military Trainees! Initial leadership development needs assessment, ave time 2.1 mins. Help me help you! @defprofmilmeduk.bsky.social @drkateking.bsky.social @edbarn.bsky.social www.surveymonkey.com/r/B7DKYHLsurveymonkey.comDefence Medical LeadershipTake this survey powered by surveymonkey.com. Create your own surveys for free. 012
Jake Matthews @jakemat91.bsky.social · 24/02/2025Dr malcolm kendrick has said very similar things. Ivor Cummins is not medical. But he is quite a smart guy who seems to have read an analysed a lot of the literature on statins. I'm not saying he is right but it's good to know both sides of the argument. 100
Reposted by Jake MatthewsDr Steve Taylor @drstevetaylor.bsky.social · 22/02/2025‘There is simply no conception (within NHS England) of how pivotal GPs are to the cost-effective performance of the health service - let alone to holistic patient care’ So says the ever-insightful @pwhitakerwriter.medsky.social www.newstatesman.com/politics/hea...newstatesman.comNHS England has no idea about GPsReform will only happen when the organisation confronts how lamentably wrong-headed it has been. 512963
Jake Matthews @jakemat91.bsky.social · 22/02/2025Can AI help with the GP job crisis in the UK? Can it simplify the international jobs market? What do you think? #TeamGP #RCGPReg #MedSky #jobs open.substack.com/pub/medicuri...open.substack.comNo99b: Can AI make searching GP jobs around the world easier to find and compare?The international market for doctors (GPs and Family Medicine) is complicated. 010
Jake Matthews @jakemat91.bsky.social · 21/02/2025What can big macs tell us about GP salaries around the world? #TeamGP #primarycare #RCGPReg #bigmacindex open.substack.com/pub/medicuri... Updated the Big Mac Index for GP salaries around the world in 2025. If anyone is considering emigratingopen.substack.comNo 99: In 2025, Which Country Has the Best GP Salary Using the Big Mac Index?Any long time readers of MediCurious ? 120
Reposted by Jake MatthewsEmma Bower @emmabower.bsky.social · 20/02/2025Bit late to post this, but this story from last week based on our annual survey of locum GPs shows how the current jobs crisis is affecting locums. In England most are struggling to find work, with many saying it has had a devastating impact on their income www.gponline.com/locum-gps-st... #GPnewsgponline.comMost locum GPs struggling to find work as jobs crisis devastates incomeMost locum GPs in England are struggling to find work amid huge competition for jobs, with many saying it has had a devastating impact on their income, a survey has found. 015
Reposted by Jake MatthewsSara Rouhi @rouhiroo.bsky.social · 16/02/2025Jake - New NIH is tip of ⛰️for what's coming. Consider SIGNING and amplifying this open declaration against exactly this kind of thing to #defendresearch? docs.google.com/forms/d/e/1F...docs.google.comDeclaration To Defend Research Against U.S. Government CensorshipThis Declaration is a call to action for the scholarly communication community and additional stakeholders to condemn and resist recent acts by the U.S. government to censor scholarly research. We ca... 001
Jake Matthews @jakemat91.bsky.social · 16/02/2025Heidi Hi Patient. Is AI about to drastically reduce the need for a GP? #TeamGP #RCGPReg #MediCurious #AI #MedSky open.substack.com/pub/medicuri...open.substack.comNo 98: Heidi Hi Patient. How can the AI assisted HCA help you today?Do you really need to see a doctor? 010
Jake Matthews @jakemat91.bsky.social · 16/02/2025#SundayReflection What is passive and active academic freedom? Not something I have come across before. #MedSky #AcademicSky open.substack.com/pub/sensible...open.substack.comActive and Passive Academic FreedomShould the NIH consider Universities commitment to free expression as it gives out funds? 110
Jake Matthews @jakemat91.bsky.social · 15/02/2025Anyone not joined #Whoop yet and want a free month? Get a free WHOOP 4.0 and one month free when you join with my link: join.whoop.com/4F5621join.whoop.comJoin WHOOPThe most advanced fitness and health wearable. Get personalized insights on your body's recovery, strain, sleep, and health with in-app coaching features designed to help you unlock your best self. 000
Reposted by Jake MatthewsBJGP @bjgp.org · 13/02/2025“People just left because they just couldn’t cope with the stress.” Digitalised work offers some benefits, but, in the current pressurised climate of UK general practice, drives workplace stress, suffering, and strain on working relationships doi.org/10.3399/BJGP... #PrimaryCaredoi.orgTechnostress, technosuffering, and relational strain: a multi-method qualitative study of how remote and digital work affects staff in UK general practice | British Journal of General Practice 3137
Jake Matthews @jakemat91.bsky.social · 09/02/2025castbox.fm/app/castbox/... This is a really good podcast summary of changes in TERS funding and GP recruitment crisis @gponline.bsky.socialcastbox.fmGP recruitment scheme faces axe, contract negotiations update, NHS planning guidance<p>In this week’s episode the GPonline team discusses the future of the Targeted Enhanced Recruitment Scheme (TERS) – an initiative to attract GPs to un... 000
Reposted by Jake MatthewsBJGP @bjgp.org · 04/02/2025Listen to BJGP Associate Editors discussing BJGP's Top 10 most read research published in the last year www.bjgplife.com/193 #BJGPTop10 #PrimaryCare @sammerriel.bsky.social l @drtomround.bsky.social @nadakhan.bsky.socialbjgplife.comBJGP’s top 10 most read papers of 2024Quickly and easily listen to BJGP Interviews for free! 076
Jake Matthews @jakemat91.bsky.social · 09/02/2025@dauk-gp.bsky.social @gppact.bsky.social @gponline.bsky.social @wisegpcouk.bsky.social @sapc.ac.uk @accurx.bsky.social Does anyone else want to collaborate on this project? Sharing templates more widely and ideally getting every useful tool and score from MDCalc and on to AccuRx. 000
Jake Matthews @jakemat91.bsky.social · 09/02/2025Collaboration request... #MedSky who can help? I want to form a group of clinicians to persuade AccuRx to allow for "community collaboration" and sharing of templates more widely? Pls like and share if you agree #MediCurious #TeamGP #MedTech #collaboration open.substack.com/pub/medicuri...open.substack.comNo 97: A Love Letter to AccuRx and a Call to Action!Please share user-made templates more widely. 101
Jake Matthews @jakemat91.bsky.social · 08/02/2025Does anyone else love time saving, technology, @Accurx and @mdcalc ? If so, please read and share. I really want to see AccuRx embrace this small change that could lead to a grass-roots revolution in the use of objective patient surveys and tools. open.substack.com/pub/medicuri...open.substack.comNo 97: A Love Letter to AccuRx and a Call to Action!Please share user-made templates more widely. 000
Jake Matthews @jakemat91.bsky.social · 08/02/2025open.substack.com/pub/preventa... This post takes 5 mins to read. It's brilliant. She lays out how we should be learning from inquests and coroners reports. And how she has developed a new website that automates the collection and reporting of the data. It's inspiringopen.substack.comTransforming learning from avoidable deathsRelaunching the Preventable Deaths Tracker 000
Reposted by Jake MatthewsMark Rubin @markrubin.bsky.social · 28/01/2025Cardiff University confirms plans to cut 400 full-time jobs That's over 1,000 job cuts planned between Cardiff, Durham, and Newcastle in the space of a week. #UKHE #AcademicSky #HigherEd #EduSkybbc.co.ukCardiff: University confirms plans to cut 400 jobsVice-chancellor Wendy Larner says 33547
Jake Matthews @jakemat91.bsky.social · 26/01/2025open.substack.com/pub/insideme... #InsideMedicine with Atul Gawande on USAID stop orderopen.substack.comLive impromptu chat with Dr. Atul Gawande.Instead of a phone call, we went Live on Instagram. On the docket: What the halt in US foreign aid means *immediately*. 010
Jake Matthews @jakemat91.bsky.social · 25/01/2025Yes. That is a big concern of mine as well. Hopefully with recent deaths being in the media maybe the MHRA will pay closer attention 🤞🤞🤞 010
Jake Matthews @jakemat91.bsky.social · 25/01/2025I suspect you may be right that they are overwhelmed. Doesn't fill you with confidence in our system though does it? Especially when we know the yellow cards actually sent are the tip of the iceberg and less that 5% (?) Of potential reactions. 110
Jake Matthews @jakemat91.bsky.social · 25/01/2025Everyone involved in healthcare in the UK should read this harrowing tale of how the MHRA Yellow Card Scheme did not work in this instance. #TTE #MedSky #yellowcard open.substack.com/pub/trustthe...open.substack.comReporting a Fatal Event to the Yellow Card SystemA sorry saga of delay and impediment 110
Reposted by Jake MatthewsDr Steve Taylor @drstevetaylor.bsky.social · 25/01/2025The failure for GPs to find work after qualifying is unacceptable Between 1/5 to 1/3 depending on year are not in any form of employment after qualifying Training more GPs without providing practices the funding to employ them is a NHS England failure digital.nhs.uk/supplementar... 45538
Reposted by Jake MatthewsAnish K Patel @anishkpatel.bsky.social · 24/01/2025Is this the modern-day NHS postcode lottery? Where you live determines your access to General Practice—if not the access itself, then the type of access. Can’t help thinking part of this is driven by inequitable funding via Carr-Hill formula. 044
Jake Matthews @jakemat91.bsky.social · 25/01/2025I know lots of GPST3 looking for work. Only 1 person I know has taken up an ARRS role. 000
Reposted by Jake MatthewsDr Steve Taylor @drstevetaylor.bsky.social · 24/01/2025There are 6322 Neighbourhood Health Centres in England GP Practices have lost 20% real terms funding since 2016, if they hadn’t they would be better able to provide the care patients need, but still 31m appts/month Fund GP practices properly & they’ll do the rest @rthonwesstreeting.bsky.social 15429
Reposted by Jake MatthewsSaloni @scientificdiscovery.dev · 23/01/2025Cardiovascular disease mortality has declined in many countries over the past decades. For example, US cardiovascular disease death rates have declined 4x since 1950. 1773645292
Jake Matthews @jakemat91.bsky.social · 23/01/2025When I was a student I emailed a few different conference organisers and was able to get free places. Don't ask, don't get. Is the work relevant to any particular charities who might support it? 010
Reposted by Jake MatthewsRebecca Payne @oohgpwales.bsky.social · 23/01/2025Am trying to find funding for a couple of medical students to present their research at academic conferences. Uni funds limited. Any idea as to where I can try? 502
Jake Matthews @jakemat91.bsky.social · 10/01/2025#MedTech #AI question for #MedSky ... Why hasn't #PUBMed or the journal publishers produced closed system AI LLM based on their journals and papers yet? Like #Google #Notebook but with all the articles full loaded. 000
Jake Matthews @jakemat91.bsky.social · 04/01/2025Resolution: Thou Shalt buy no more books until thy has finished the top shelf 000
Jake Matthews @jakemat91.bsky.social · 04/01/2025bjgp.org/content/75/7... @bjgp.bsky.social Great article by Dr Evans. I'd never heard of the book Medical Nemesis but he explains it well and certainly provokes some thoughts about the limits of modern medicinebjgp.orgIvan Illich’s Medical Nemesis at 50This year sees the 50th anniversary of the publication of Medical Nemesis: The Expropriation of Health by Ivan Illich,1 a book that has had the same impact on the language of health care as George Orw... 000
Jake Matthews @jakemat91.bsky.social · 03/01/2025If you want to study statins, then you need to start with the key studies, listed here: medicurious.substack.com/p/no-96-why-... 000
Jake Matthews @jakemat91.bsky.social · 01/01/2025The first post of 2025 and its another struggle with statins. I still have some questions that I would love to have some help with. open.substack.com/pub/medicuri... #MediCurious #EBM #statinsopen.substack.comNo 96: Why is Luther causing me Statin troubles?Welcome to 2025! 010
Jake Matthews @jakemat91.bsky.social · 31/12/2024www.cochrane.org/CD004816/VAS... @cochranecochrane.orgStatins for the primary prevention of cardiovascular disease 000
Jake Matthews @jakemat91.bsky.social · 31/12/2024bsky.app/profile/jake... Huge thread, listing summary of major papers, trials and reviews of #statins and #primaryprevention Tried something new. Using BlueSky as a notepad. Is this useful for #MedEd and #EBM ? 120
Jake Matthews @jakemat91.bsky.social · 31/12/2024high-intensity atorvastatin has an early and significant impact on lipoproteins and apolipoproteins but did not lower inflammatory, thrombogenic or biomarkers of platelet activity and aggregation in women with metabolic syndrome. pubmed.ncbi.nlm.nih.gov/33485731/pubmed.ncbi.nlm.nih.govEffect of atorvastatin on lipogenic, inflammatory and thrombogenic markers in women with the metabolic syndrome - PubMedIn conclusion, high-intensity atorvastatin has an early and significant impact on lipoproteins and apolipoproteins but did not lower inflammatory, thrombogenic or biomarkers of platelet activity and a... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024We also compared #WOSCOPS findings with those of the Scandinavian Simvastatin Survival Study (4S) and the Medical Research Council (MRC) trial of treatment for mild to moderate hypertension in middle-aged men. pubmed.ncbi.nlm.nih.gov/8918276/pubmed.ncbi.nlm.nih.govWest of Scotland Coronary Prevention Study: identification of high-risk groups and comparison with other cardiovascular intervention trials - PubMedThere were a substantial number of men whose risk of a coronary event was more than 10% at 5 years in the WOSCOPS cohort. The absolute benefit of pravastatin treatment of hyperlipidaemia is less in th... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024CAC assessment may positively influence patients and physicians to improve risk factor control. pubmed.ncbi.nlm.nih.gov/34482089/pubmed.ncbi.nlm.nih.govImpact of a coronary artery calcium-guided statin treatment protocol on cardiovascular risk at 12 months: Results from a pragmatic, randomised controlled trial - PubMedParticipants unblinded to their CAC showed reductions in LDL irrespective of statin continuation when compared to controls at 12 months. Improvements in individual risk factors and PCE risk were also ... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024Effectiveness of a Proactive Cardiovascular Primary Prevention Strategy, With or Without the Use of Coronary Calcium Screening, in Preventing Future Major Adverse Cardiac Events #CorCal CAD scanning seems to improve statin adherence pubmed.ncbi.nlm.nih.gov/34922872/pubmed.ncbi.nlm.nih.govCoronary Artery Calcium Versus Pooled Cohort Equations Score for Primary Prevention Guidance: Randomized Feasibility Trial - PubMedCAC guidance may be a more efficient, personalized, cost-effective, and motivating approach to statin initiation and maintenance in primary prevention. This feasibility phase of CorCal should be regar... 200
Jake Matthews @jakemat91.bsky.social · 31/12/2024pubmed.ncbi.nlm.nih.gov/35218726/ Protocol of trying CAD and a polygenic risk score in intermediate risk patients for primary preventionpubmed.ncbi.nlm.nih.govUse of coronary computed tomography or polygenic risk scores to prompt action to reduce coronary artery disease risk: the CAPAR-CAD trial - PubMedAs of July 31, 2021, we have screened 1,903 individuals. We present the results of the 574 participants deemed eligible after baseline assessment. 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024pubmed.ncbi.nlm.nih.gov/16846539/ #AVIATOR study found that informing clinicians of Framingham 10 year risk score did not increase statin prescriptions in high risk patients but did in medium risk patients.pubmed.ncbi.nlm.nih.govEffects of a global risk educational tool on primary coronary prevention: the Atherosclerosis Assessment Via Total Risk (AVIATOR) study - PubMedAlthough a simple global risk educational tool did not improve the targeting of statin therapy to patients at high absolute coronary risk, it may be of benefit in targeting moderate-risk individuals w... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024apoAI to form the apoB/AI ratio, may be a more accurate predictor than LDL-C of risk for first AMCE. #AFCAPS /TexCAPS pubmed.ncbi.nlm.nih.gov/10662743/pubmed.ncbi.nlm.nih.govRelation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) - PubMedPersons with average TC and LDL-C levels and below-average HDL-C may obtain significant clinical benefit from primary-prevention lipid modification. On-treatment apoB, especially when combined with ap... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024pubmed.ncbi.nlm.nih.gov/20543522/ #MEGA study limited dose response benefitpubmed.ncbi.nlm.nih.govAssociation between lowering low-density lipoprotein cholesterol with pravastatin and primary prevention of cardiovascular disease in mild to moderate hypercholesterolemic Japanese - PubMedThe usual Japanese dose of pravastatin therapy is sufficient in this low-risk patient population to reduce cardiovascular risk, with an achieved LDL-C level <133.4 mg/dL. Further risk reduction was no... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024pubmed.ncbi.nlm.nih.gov/11430324/ High CRP is predictive of MACE. Statins in primary prevention reduced CRP sig. High LDL but low CRP baseline, statins were ineffective. But were effective when CRP was raised.pubmed.ncbi.nlm.nih.govMeasurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events - PubMedStatin therapy may be effective in the primary prevention of coronary events among subjects with relatively low lipid levels but with elevated levels of C-reactive protein. 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024#KAPS (Kuopio Atherosclerosis Prevention Study) is the first population-based trial in the primary prevention of carotid and femoral atherosclerosis published in 1995 pubmed.ncbi.nlm.nih.gov/7671358/ The effect was larger with higher baseline IMT, smokers and low plasma vitamin E levelspubmed.ncbi.nlm.nih.govKuopio Atherosclerosis Prevention Study (KAPS). A population-based primary preventive trial of the effect of LDL lowering on atherosclerotic progression in carotid and femoral arteries - PubMedThese data establish the antiatherogenic effect of LDL-C lowering by pravastatin in hypercholesterolemic men in a primary prevention setting and suggest a greater effect in smokers than in nonsmokers. 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice #EURIKA Patients on statins more likely to have uncontrolled BP pubmed.ncbi.nlm.nih.gov/27232917/pubmed.ncbi.nlm.nih.govLack of control of hypertension in primary cardiovascular disease prevention in Europe: Results from the EURIKA study - PubMedOver 50% of patients treated for hypertension continued to have uncontrolled blood pressure and 14.3% had apparent resistant hypertension. Positive associations were seen with other cardiovascular ris... 100
Jake Matthews @jakemat91.bsky.social · 31/12/2024#WOSCOPS recruits are, on average, 7 to 9 years older than subjects in other trials and have average total cholesterol levels 0.5 mmol/L (19.4 mg/dl) lower than those in the #Helsinki Heart Study and the Lipid Research Clinics-Coronary Primary Prevention Trial. pubmed.ncbi.nlm.nih.gov/7653449/pubmed.ncbi.nlm.nih.govScreening experience and baseline characteristics in the West of Scotland Coronary Prevention Study. The WOSCOPS Study Group. West of Scotland Coronary Prevention Study - PubMedThe West of Scotland Coronary Prevention Study (WOSCOPS) is a randomized, double-blind, placebo-controlled trial of pravastatin in a primary prevention context. The primary end point of the trial is d... 100
