bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

Mouse models of lung and colorectal cancer with sporadic DNA mismatch repair deficiency clarify that the intratumor heterogeneity and clonal architecture rather than tumor mutational burden are powerf...

An immune-related gene variant has been tied to a reduced risk of Alzheimer's and Parkinson's across a huge, diverse population of people.

I have a confession to make: I am now a Python user. Don't judge me, join me! In this post, I introduce Python for data analysis from the perspective of an R (tidyverse) user.

A study describing an approach that combines imaging and profiling techniques to structurally and functionally analyse lung cancer in vivo, revealing heterogeneous mitochondrial networks and an a...

Regulatory T (Treg) cells play vital roles in immune homeostasis and response, including discrimination between self- and non-self-antigens, containme…

Beets et al. present a system-wide resource of 461 peptide-GPCR couples in C. elegans, revealing binary and complex combinatorial signaling motifs in the peptide-receptor network, which provide insi...