iiinova — where your digital self keeps evolving

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nvansorge.bsky.social @nvansorge.bsky.social · 09/01/2026

📣 What is the impact of expanded antibiotic prophylaxis during an iGAS surge? Read it in our new publication: jamanetwork.com/journals/jam... By expanding antibiotic prophylaxis to household contacts of all iGAS patients, secondary household infections were reduced by 83%.

jamanetwork.com

Secondary Invasive Group A Streptococcal Infection After Prophylaxis Policy Change

This cohort study estimates the risk of invasive group A streptococcus (iGAS) before and after the implementation of a policy in the Netherlands that expanded antibiotic prophylaxis to household conta...

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 11/01/2026

New Year's 2026 Party and this year's Lab T-Shirt

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Grampospath @grampospath.bsky.social · 15/10/2025

Definitely worth a read and raises all sorts of questions about how quickly we become vulnerable as a population if we aren’t immune/immunised.👇

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Alex Keeley @alexjkeeley.bsky.social · 08/08/2025

🧵 Our paper out today in @naturemedicine.bsky.social www.nature.com/articles/s41... On development of #StrepA #Immunity over life course in #TheGambia raising hope for #vaccines on the horizon 1/ #Immunosky #IDsky #MicroSky #globalhealth.

nature.com

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Nikki Moreland @njmoreland.bsky.social · 08/12/2025

Our latest work used Phip-Seq to explore the autoantibody repertoire in rheumatic fever ➡️ saw evidence of epitope spreading and identified a new disease associated antigen with biomarker potential 🧪 Great collaboration with MSSM and led by @rhcmcg.bsky.social and @laurencarlton.bsky.social at UoA

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 05/01/2026

This paper has everything I could wish for in a scientific insight! Puppy ➡️ Strep ➡️ Happiness Dog ownership in adolescents was associated with fewer social problems and altered gut microbiota. Notably, a Streptococcus ASV correlated with sociability in both adolescents and ex-germ-free mice.

cell.com

Dog ownership during adolescence alters the microbiota and improves mental health

Microbiome; Psychology

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 04/07/2025

New @plosbiology.org paper from Sumedha Ravishankar, PhD and the Cressida Madigan Lab applies the powerful and optically transparent zebrafish embryo model to study group B streptococcal transit of the blood-brain barrier. Beautiful time-lapse confocal microscopy! journals.plos.org/plosbiology/...

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Dr Danika Hill @precisionvaxlab.bsky.social · 04/04/2025

New preprint alert 🚨 My team and I are pleased to share our most recent story about how bacterial pathogen (Streptococcus pyogenes, Strep A) exposure induces antibody responses against glycan and protein antigens. For paper: SSRN ssrn.com/abstract=519... biorxiv : doi: doi.org/10.1101/2025...

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JAMA @jama.com · 07/04/2025

From 2013 to 2022, invasive group A Streptococcus infections increased in 10 US states, with higher incidence among older adults, American Indian or Alaska Native persons, and vulnerable groups. ja.ma/3G9OPT2

ja.ma

Invasive Group A Streptococcal Infections in 10 US States

This population-based surveillance study investigates trends in the incidence, characteristics, antimicrobial resistance, and outcomes of invasive group A Streptococcus infections among individuals in 10 US states.

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 13/03/2025

Rheumatic heart disease arises from repeated Group A Strep infections, leading to autoimmune heart damage. New research advances knowledge of its progression, offering hope for better interventions. Review by Adrien Lupieri et al, LeDucq Foundation PRIMA Network www.frontiersin.org/journals/car...

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Josh Osowicki @joshosowicki.bsky.social · 19/11/2024

🔥❤️‍🔥🔥❤️‍🔥 #LISSSD25 in Brisbane. Get in line (in pairs or chains) and get moving on your abstracts (open NOW). if your research relates to any -ology of catalase negative Gram + cocci (starts with Strep*) with an impact on human health - you belong at #LISSSD25!!!! www.lisssd2025.org/abstract-sub...

lisssd2025.org

Abstract Submission — LISSSD 2025

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Josh Osowicki @joshosowicki.bsky.social · 03/02/2025

Abstract submission extended 72h until Wed Feb 5th 1159 pm 🇦🇺 EDT. >300 abstracts submitted so far! Get yours in! mailchi.mp/f0e900990ac5...

mailchi.mp

LISSSD 2025 | Abstracts Extended 72HRS

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Nikki Moreland @njmoreland.bsky.social · 15/12/2024

Following relaxation of #COVID19 restrictions surges in infections from respiratory pathogens like RSV and #StrepA have been seen in many countries including Aotearoa New Zealand. Did waning immunity contribute? We explored this concept in our latest work, see 🧵 academic.oup.com/jid/advance-...

academic.oup.com

Decline of antibodies to major viral and bacterial respiratory pathogens during the COVID-19 pandemic

Antibodies to respiratory syncytial virus and Group A Streptococcus waned significantly in a longitudinal cohort throughout the pandemic. This waning may h

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 22/12/2024

INVASIVE GROUP A STREP HAS BEEN AROUND A LONG TIME Hippocrates 5th century BC EPIDEMICS III “Early in the spring—at the same time as the cold snaps which occurred—were many malignant cases of erysipelas, some from a known exciting cause and some not. Many died—and many suffered pain in the throat”

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · 28/11/2024

Hey Group A Strep Fans New in Nature Communications from Di Tang in Johan Malmström Lab in Lund Sweden Streptolysin O binds plasminogen, inducing conformational shifts that enhance plasminogen activation, revealing a conserved role beyond its cytolytic activity! www.nature.com/articles/s41...

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iSpy Explore @ispyexplore.bsky.social · 18/12/2024

We're live! The iSPY Explore Network is on a mission to uncover immune correlates of streptococcal infection. Join us on this exciting journey of discovery! #StrepResearch #iSPYExplore #UCSanDiego

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