iiinova — where your digital self keeps evolving

Reposted by Chloe📡

Best of r/cybersecurity @cybersecurity.page · 22/08/2026

Grok carries out malicious instructions when they are encoded, exfiltrating user data. Guardrails only catch plaintext, so base64 and similar tricks bypass them. The AI crowd skipped security lessons.

reddit.com

Grok exfiltrates user data when malicious instructions are encrypted

View post on Reddit.

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Reposted by Chloe📡

𝕭𝖊𝖒𝖎𝖑𝖞 @skeeterpond.bsky.social · 22/08/2026

truck stop kratom got me acting like moominmamma

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Chloe📡 @interferometry.bsky.social · 18/08/2026

Here's a LEGO mecha I made a while ago.

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Reposted by Chloe📡

Kate Lingley 龍梅若 @klingley.bsky.social · 12/08/2026

Buddhism in the wild (photo by Jerry Feldman, Target Honolulu)

View of an end-cap display at Target, with a sign above it saying “Must have!” The shelves are empty.

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Chloe📡 @interferometry.bsky.social · 10/08/2026

Took them like 10 minutes to get cozy. They need a larger hammock!

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Chloe📡 @interferometry.bsky.social · 08/08/2026

Hard Boiled asks the question 'what if guns had infinite bullets' and answers with 'we would get all into jazz music about it'

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Chloe📡 @interferometry.bsky.social · 07/08/2026

These absolute divas in the Science Saru 'Ghost In The Shell' episode 5 I'm gagged

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Reposted by Chloe📡

headfallsoff @headfallsoff.com · 06/08/2026

this is the most 2007 youtube video ever made. you are not prepared. every line you will think well surely thats the most insane and the rest are normal but no. its every single line. if you want to understand america in 2007 watch "the halo 3 hoedown" i guess

youtube.com

The Halo 3 Hoedown

YouTube video by Doc Adams

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Reposted by Chloe📡

Jive XXL @jivexxl.bsky.social · 05/08/2026

for those who celebrate: it is the 20th anniversary of a funny dog eat a pepsi.

A funny dog eat a pepsi.. This is so funny picture

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Reposted by Chloe📡

dec @1milliondollars.bsky.social · 04/08/2026

we need a navigator to get us through the planet's core. this gay gungan may be of help

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Reposted by Chloe📡

Suw @suw.bsky.social · 02/08/2026

Crops grown underneath solar panels produce more, require less water and are more resistant to extreme weather, even during a hot, dry summer. We need agrivoltaics to be rolled out asap, for both the electricity and the better growing conditions. microgridmedia.com/solar-panels...

microgridmedia.com

Solar Panels Are Helping Crops Grow Better, Global Studies Show - Microgrid Media

For farmers worried about losing land to solar energy, new research brings surprising news: many crops actually produce more food when grown beneath solar

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Chloe📡 @interferometry.bsky.social · 26/07/2025

Big Thief? Must be hard to avoid detection

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Chloe📡 @interferometry.bsky.social · 18/06/2025

Getting absolutely maggot at stereo

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Reposted by Chloe📡

Hello Meteor @hellometeor.bsky.social · 20/05/2025

𝗜𝗠𝗣𝗔𝗖𝗧 𝗕𝗟𝗢𝗢𝗠 𝘢𝘷𝘢𝘪𝘭𝘢𝘣𝘭𝘦 𝘦𝘷𝘦𝘳𝘺𝘸𝘩𝘦𝘳𝘦 hellometeor.com/bloom new merch is up, new stories available.

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Reposted by Chloe📡

Carl Sagan @carlsagandotcom.bsky.social · 09/05/2025

“The suppression of uncomfortable ideas may be common in religion or in politics, but it is not the path to knowledge, and there's no place for it in the endeavor of science.” - Carl Sagan

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Chloe📡 @interferometry.bsky.social · 08/05/2025

The first pope who has ever drank Jepsen's Malort

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Reposted by Chloe📡

Aftermath @aftermath.site · 04/04/2025

Psycho Patrol R, now in early access, is a hilarious, Finland-coded, euro-septic vision of our horrible future and one of the best immersive sims I've played in ages. aftermath.site/psycho-patrol-...

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Reposted by Chloe📡

Lora Kolodny @lorak.bsky.social · 03/04/2025

“the economic return on federal funding for research has been staggering. According to one recent estimate, government investment in research and development accounted for at least 20 percent of American productivity growth since World War II…” www.thecrimson.com/article/2025...

thecrimson.com

To Kill a University | Opinion | The Harvard Crimson

Killing American universities, arguably the greatest innovation engines in human history, will not only destroy higher education as a catalyst for social progress, it may also forever cripple the Amer...

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Reposted by Chloe📡

Randall Munroe @xkcd.com · 21/03/2025

Cosmic Distance Calibration xkcd.com/3066

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Chloe📡 @interferometry.bsky.social · 21/02/2025

Thorium Powered Molten Salt Reactors are a human right

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Chloe📡 @interferometry.bsky.social · 12/02/2025

NME magazine was wild back in the day. I asked Stuart once if he remembered if Rick was a good kisser and he said he didn't remember 😂

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Chloe📡 @interferometry.bsky.social · 11/02/2025

There's a sort of metaphor to this image that I think relates to any democracy supporter atm

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Chloe📡 @interferometry.bsky.social · 31/01/2025

Telling my kids this was Elton John or something idk

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Reposted by Chloe📡

Morgan Tingley @mwtingley.bsky.social · 08/01/2025

The insanity of being a fire ecologist in the epicenter of a major fire event, bags packed and ready to evacuate, watching active fire from my window, while taking media requests and explaining to the public, for the 100,000th time how climate change is largely responsible for this

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Reposted by Chloe📡

Chise @sailorrooscout.bsky.social · 02/01/2025

Stanford researchers have found a way to trick our immune systems into paying attention to all four subtypes represented in the vaccine. Here’s how it works:

B-cells- the immune cells that serve as our body's antibody factories- are ultrapicky about exactly which antibodies they make. An individual B-cell will produce only a single species of antibody fitting a mere one or very few antigenic shapes. That B-cell is just as picky about what antigen it will pay attention to: that is, precisely the antigen the B-cell's antibodies will stick to. When this antigen comes along, the B-cell recognizes it and gobbles it up.
That's step one.
Next, the B-cell chops the antigen up into tiny strips called peptides, which it displays on its surface for inspection by roving immune cells called helper T-cells, whose follow-on stimulatory services are critical for turning antigen-displaying B-cells into antibody-spewing B-cells.
Helper T-cells are just as finicky as B-cells. A helper T-cell will sprinkle its stardust only on B-cells displaying antigen-derived peptides that particular T-cell is designed to respond to- and even then, only when that peptide is gripped by one of the matching molecular jewel cases that B- cells produce in myriad varieties.
But different peptides require different jewel cases.
And depending on their luck in the genetic draw, people's repertoires of those specialized jewel cases vary from one person to the next, leaving many of us with plenty of the jewel cases that match peptides from one influenza-subtype hemagglutinin but far fewer of those that match another flu subtype's peptides.

In the standard flu vaccine formulation, the four antigens corresponding to the four common subtypes are delivered as separate particles in a mix. To overcome subtype bias, researchers stitched all four antigens together. They designed a vaccine in which the four hemagglutinin varieties are chemically conjoined on a molecular matrix scaffolding. That way, any B-cell that recognizes and begins ingesting one or another of the vaccine's four hemagglutinin types ends up wolfing down the entire matrix and displaying bits of all four antigens on its surface, persuading the immune system to react to all of them despite its predisposition not to.
Forcing B-cells to "eat their vegetables" - internalize all four hemagglutinin subtypes instead of just the one that tastes best- effectively multiplies the number of B-cells displaying hemagglutinin-derived peptides from every subtype on their surfaces, albeit still in a ratio skewed by the B-cells' uneven inventories of jewel-case molecules.
This, in turn, makes helper T-cells much more likely to stumble on a sample from the antigen they love to hate. They fire up, start multiplying feverishly, branch out in pursuit of any B-cells displaying that antigen and spur antibody production in them. These selected B-cells also proliferate, culminating in bulk production of antibodies that are likely to stop the influenza virus-whatever its subtype- in its tracks.

Supplementary figure 1: A multivariate regression model was developed to estimate the post-vaccination (day 28, d28) HAI response using baseline (day 0, dO) HAl titer, age, and sex. The geometric mean titer (GMT) for each individual at baseline (dO) and post-vaccination (d28) was calculated based on HAl titers against all influenza virus strains in the vaccine formulation.

Supplementary figure 2: Sankey flow diagrams depict the change in HAl response for each donor after vaccination, for the different vaccine subtypes: (A) H1, (B) H3, and (C) B. The lines connect the baseline (day 0) and post-vaccination (day 28) HAl titers for each donor.

Supplementary figure 3: Association of (A) Age and (B) Sex with subtype-bias after seasonal influenza vaccination. The UMAP plot rendering is identical to Figure 1(A). The adjusted p-values to compare the distribution of age across different groups was calculated using one-way ANOVA with Tukey test for pairwise comparisons. The p-value for sex distribution across different groups was calculated by two-tailed Fisher's exact test. Not significant (n.s.).

Supplementary figure 4: Subtype-specific responses in high responders. (A) Post-vaccination (day 28) HAI titers are shown using box plots. The mean fold-change in HAl titer against the vaccine subtypes is also given. Adjusted p-values were calculated using one-way ANOVA with Tukey's test for pairwise comparisons. The fold-change (day 7/day 0) in CD4+ cTh activation against the vaccine subtypes in response to vaccination after stimulation with (B) Strain-specific,
and (C) Conserved, subtype-specific HA peptides are shown using box plots (n = 9). Adjusted p-
values were calculated using one-way ANOVA with Holm-Sidak test for pairwise comparisons.
Not significant (n.s.).

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Chloe📡 @interferometry.bsky.social · 02/01/2025

If HxNy gets solved for, generally, it will be an incredible breakthrough in virology, Nobel worthy

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Reposted by Chloe📡

Dan Yocum. Ugh. @yocum137.bsky.social · 25/12/2024

In 1994 when I worked at Kitt Peak National Observatory, @todlauer.bsky.social made an off-hand comment about grape plasma in the microwave. Being an experimental physicist (read as “nerd”) I immediately tried it during night lunch. Who knew it was come to this? 🧪🔭⚛️

interestingengineering.com

Grapes double sensor magnetic power in an epic quantum breakthrough

Grape pairs boost quantum sensor performance by enhancing magnetic fields, aiding compact and cost-effective sensor development.

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Chloe📡 @interferometry.bsky.social · 24/12/2024

I'm on an emo cookie diet. I made you a cookie but I eated it

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Chloe📡 @interferometry.bsky.social · 11/12/2024

Titania is literally me. Goated Lady imo

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Chloe📡 @interferometry.bsky.social · 11/12/2024

The strange thing that keen eyes can see is that as soon as reputable journalists started coming here, the right wing bot army followed suit. There is a concerted effort to dethrone the concept of fact and truth. But those are just tea leaves I'm reading

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Reposted by Chloe📡

AltYellostoneNatPar @altyellonatpark.org · 06/12/2024

Somebody somewhere Needs flowers tonight

fields of flowers stretching off into the distance

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Chloe📡 @interferometry.bsky.social · 03/12/2024

How it feels to get dropped off at school by your parent after a doctors appointment

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