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Infinity Bio Inc

@infinitybioinc.bsky.social
29 followers 84 following 72 posts

Leading provider of antibody reactome services. Catalog antigen libraries include human proteome, virome & allergome. Custom library creation also possible! Check us out: www.infinitybio.com

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Infinity Bio Inc @infinitybioinc.bsky.social · 08/09/2026
Cohort of the Week! von Stemann et al. mapped the genetics of anti-cytokine autoantibodies to cancer protection and metabolic risk. Seromic profiling adds the critical environmental layer, offering powerful multi-omic insights into autoimmunity. rdcu.be/b4nyEn1C5Cha
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Infinity Bio Inc @infinitybioinc.bsky.social · 26/08/2026
New Cohort of the Week! Bellomo et al. prove a simple blood draw can differentiate AD, DLB & FTD using plasma #Proteomics. Combining this with antibody reactomics offers key multi-omic insights into the systemic immune dialogue driving #Neurodegeneration. rdcu.be/fAFt0
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Infinity Bio Inc @infinitybioinc.bsky.social · 18/08/2026
Are circulating proteins static fingerprints or dynamic state markers? New Nat Comms data shows they're both. Antibody reactomics adds this same depth to longitudinal cohorts, capturing lifelong immune memory alongside dynamic responses to new encounters. rdcu.be/fzmKA #Proteomics #AgingResearch
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Infinity Bio Inc @infinitybioinc.bsky.social · 13/08/2026
Infinity Bio's Cohort of the Week shows systemic autoantibodies mirror neurodegeneration in AD, PD & MS. Broadly profiling self, viral & environmental reactivities unlocks system-wide biomarkers. doi.org/10.1016/j.is...
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Infinity Bio Inc @infinitybioinc.bsky.social · 04/08/2026
For our Cohort of the Week, a landmark Cell study shows biological baselines aren't fixed. Layering #antibody responses to 37 microbial antigens over deep #MultiOmics gave unique insight into how geographic exposure history drives biological aging. doi.org/10.1016/j.ce...
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Infinity Bio Inc @infinitybioinc.bsky.social · 14/07/2026
How does a lifetime of environmental exposures shape how we age? By adding antibody #Reactomics to plasma #Proteomics, we can map immune history to see how past infections contribute to #CellularAging and chronic disease. Potentially transformational. doi.org/10.1038/s415...
doi.org
Plasma proteomic signatures of cellular aging predict human disease - Nature Medicine
The biological age of individual cell types can be evaluated using plasma proteomics, revealing diverse aging profiles across more than 40 cell types and links between the accelerated aging of specifi...
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Infinity Bio Inc @infinitybioinc.bsky.social · 23/06/2026
A landmark study in Cell tracks proteomic signals to predict lung cancer 5+ years early. Want the full picture? Adding Infinity Bio’s antibody reactomics uncovers the precise infectious & environmental triggers contributing to the inflammatory response tracked by proteomics analysis.
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Infinity Bio Inc @infinitybioinc.bsky.social · 16/06/2026
New research in Cell Reports Medicine identifies specific gut species linked to Type 2 Diabetes risk. But an important question remains: does the host's immune response actively prevent or allow this microbial colonization? doi.org/10.1016/j.xc... Antibody reactomics can help solve this mystery.
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Infinity Bio Inc @infinitybioinc.bsky.social · 02/06/2026
By mapping proteomes across 5 major cohorts, a new Nature Aging study shows how APOE2 & APOE4 shape Alzheimer’s through entirely different pathways. Multi-omic profiling is unlocking hidden disease mechanisms. What omic layers are your cohort missing? rdcu.be/fkVs9
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Infinity Bio Inc @infinitybioinc.bsky.social · 26/05/2026
A landmark study on the new HHGP-HK Asian cohort revealed that standard health scores like PhenoAge fall short outside European populations. Large, diverse cohorts are critical to uncovering true global disease associations and validating biomarkers for everyone. #PrecisionMedicine
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Infinity Bio Inc @infinitybioinc.bsky.social · 19/05/2026
Large, diverse cohorts are vital for #PrecisionMedicine. "Matching" gut #Microbiome fingerprints across 674 geographical diverse #Melanoma patients creates accurate treatment outcome predictions. These microbial markers provide a durable benchmark for #Immunotherapy success. doi.org/10.1016/j.ce...
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Infinity Bio Inc @infinitybioinc.bsky.social · 12/05/2026
Large diverse cohorts are the engine of #PrecisionMedicine New research using the #UCLAATLAS Biobank proves that ancestry-diverse genomic data uncovers novel disease associations, such as previously unreported risk loci. What other health critical ancestral differences await discovery?
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Infinity Bio Inc @infinitybioinc.bsky.social · 21/04/2026
New study in Nature shows #ImmuneAgeing starts early with T cell reprogramming and GATA3 activity. Adding antibody reactome profiling to these cohorts can reveal the extrinsic viral and environmental triggers of #Aging —a vital layer for the #MultiOmics stack. rdcu.be/fcrJT #HumanHealth
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Infinity Bio Inc @infinitybioinc.bsky.social · 14/04/2026
A new #HumanImmuneHealthAtlas published in Nature reveals that #ImmuneAgeing is a non-linear process starting earlier than we thought. By mapping these molecular transitions, we can better tailor vaccines and therapies to biological age, not just the clock. rdcu.be/fcrJT #Immunology #SystemsBiology
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Infinity Bio Inc @infinitybioinc.bsky.social · 07/04/2026
A new @cellcellpress.bsky.social study of 2,279 brain samples reveals deep molecular diversity in #Neurodegeneration. By mapping #Proteomics & PTMs, we move closer to #PrecisionMedicine and improved stratification between seemingly similar neurodegenerative diseases. www.cell.com/cell/fulltex...
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Infinity Bio Inc @infinitybioinc.bsky.social · 31/03/2026
New research in @natmed.nature.com reveals IgG1 producing #Bcells are key to cancer #immunotherapy success. Data from 2k+ patients show these cells coordinate with T-cells to drive anti-tumor immunity. A shift toward humoral-cellular strategies could transform outcomes. rdcu.be/e90xd
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Humoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockade
Nature Medicine - Transcriptomic and clinical data analyses from multiple cohorts of patients with cancer receiving immunotherapy find that PD-1 blockade potentiates tumor-specific IgG1 plasma cell...
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Infinity Bio Inc @infinitybioinc.bsky.social · 24/03/2026
New study from #LifelinesNEXT cohort: a map of 31k+ gut viruses in mother-infant pairs. Key findings: vaginal birth & breastfeeding drive viral diversity, linked to future allergy risk. Large-scale longitudinal measurements generate unique findings for human health. doi.org/10.64898/202...
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Infinity Bio Inc @infinitybioinc.bsky.social · 18/03/2026
Thrilled to welcome Brian McKelligon as the new CEO of Infinity Bio! Brian's leadership will accelerate the reach of our #MIPSA technology and the inSIGHTs it delivers to researchers worldwide. Welcome to the team, Brian! #InfinityBio #AntibodyReactomics www.businesswire.com/news/home/20...
businesswire.com
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Infinity Bio Inc @infinitybioinc.bsky.social · 17/03/2026
#MultipleSclerosis progression insights via #proteomic profiling: New study on MS reveals anti-viral response as a continuous disease driver, implicating #EBV infection beyond just a trigger. Highlights include sex-specific pathways for injury, repair & resilience. rdcu.be/e7ZWe #MSResearch
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Infinity Bio Inc @infinitybioinc.bsky.social · 13/03/2026
Infinity Bio's Katy Shaw-Saliba & Ben Larman just published a new study screening 85 Ig batches against 283,000+ viral peptides, uncovering pandemic-driven immune shifts & autoantibody changes. Discoveries like this begin with decoding the antibody reactome. doi.org/10.1002/eji....
doi.org
Viral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic Era
Immunoglobulin products derived from pooled global plasma reflect population-level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic-driven shifts in viral antibody profiles ...
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Infinity Bio Inc @infinitybioinc.bsky.social · 13/03/2026
Researchers identified proteomic markers for #LymphoidCancer risk up to 10yrs before diagnosis. This large-scale discovery reveals how early molecular signatures like sCD23 can drive risk stratification & #EarlyDetection rdcu.be/e6GBZ%E2%80%8B #Proteomics #PrecisionMedicine #Biomarkers #Lymphoma
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Infinity Bio Inc @infinitybioinc.bsky.social · 03/03/2026
New research in #SjogrensDisease uses salivary & serum #Proteomics to link biomarkers with #HLA alleles and autoantibodies. Large-scale, multi-omic analysis like this reveals a dynamic immune record, paving the way for high-resolution patient stratification. doi.org/10.1016/j.ar...
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Infinity Bio Inc @infinitybioinc.bsky.social · 24/02/2026
Groundbreaking study in @natmetabolism.nature.com uses #MultiOmics to reveal #genes & #proteins causal to #T2D. With 85% of effects tissue-specific, large-scale profiling across ancestries is key to unlocking #global therapeutic targets. rdcu.be/e4zRC #PrecisionMedicine #TranslationalResearch
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Infinity Bio Inc @infinitybioinc.bsky.social · 17/02/2026
New Cohort of the Week from @nataging.nature.com! By analyzing nearly 1,000 human CSF samples, researchers mapped thousands of protein changes linked to #BrainAging and AD. #Proteomics on large human cohorts set the foundation for CNS markers of an aging brain. pmc.ncbi.nlm.nih.gov/articles/PMC...
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Infinity Bio Inc @infinitybioinc.bsky.social · 10/02/2026
A new study in @natcomms.nature.com re-analyzed WGS data from ~750k individuals to find viral "dark matter". By mapping viral reads, researchers linked persistent #EBV to #chronicdiseases like Lupus and Dementia. Large-scale omics are key to unlocking new disease #biomarkers Article: rdcu.be/e2cAt
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Infinity Bio Inc @infinitybioinc.bsky.social · 27/01/2026
New study in @natcomms.nature.com: A 29-protein blood signature predicts #cancer in patients with vague symptoms. Crucially, it distinguishes malignancy from #autoimmune & infectious diseases. A vital triage tool to prioritize life-saving diagnostics. #PrecisionMedicine Read: rdcu.be/eZ6bE
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Infinity Bio Inc @infinitybioinc.bsky.social · 20/01/2026
A new study leverages a well characterized infant cohort to explore our #microbiome & immune health. Researchers analyzed 647 infants in the #COPSAC cohort & found environmental exposure (daycare, siblings) reduced anellovirus abundance, consistent with immune "training." #Virome #ImmuneSystem
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Infinity Bio Inc @infinitybioinc.bsky.social · 13/01/2026
New Nature Medicine research maps blood #biomarkers related to #aging. By analyzing 54 biomarkers related to accumulated disease over 15 years, researchers identified key "biological signatures" predictive of aging. Large cohort studies are transformative for predictive health! #geroscience
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Infinity Bio Inc @infinitybioinc.bsky.social · 06/01/2026
New research reveals a link between Epstein-Barr virus (EBV) & Primary Sclerosing Cholangitis. Systematic #immuneprofiling shows that #PSC associated T & B cells target #EBV, suggesting it may drive pathogenesis. www.nature.com/articles/s41... #Omics #LiverDisease #Autoimmunity #Bcell #Tcell
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Infinity Bio Inc @infinitybioinc.bsky.social · 16/12/2025
Great news in neurodegeneration research! Hok-A-Hin et al. used large-scale CSF proteomics on a multicenter cohort to identify new biomarkers for Frontotemporal Dementia (FTD). Importantly, identified biomarker panels distinguish FTD from Alzheimer’s in presymptomatic cases. lnkd.in/eatVVT6K
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Infinity Bio Inc @infinitybioinc.bsky.social · 10/12/2025
New research sheds light on the food allergy. Gill, et al. found that children with food sensitization have gE B-cells that are less mature, more diverse. This was abrogated (stopped) by having a pet dog in the first year of life, supporting the hygiene hypothesis. doi.org/10.1111/all....
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Infinity Bio Inc @infinitybioinc.bsky.social · 02/12/2025
Cohort of the Week: Exciting new study on a large cohort of Guillain-Barré syndrome patients. Glycolipid complex auto-antibody patterns cluster into groups linked to clinical features. A step towards personalized medicine for the diagnosis, prognosis, & treatment of GBS. doi.org/10.1093/brai...
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Infinity Bio Inc @infinitybioinc.bsky.social · 18/11/2025
Lupus (SLE) symptoms are notoriously varied. New research groups patients into 6 'serological subsets' based on autoantibody profiles. Links to genetic factors (NCF2, HLA) help predict specific outcomes, like blood disorders or lower rates of kidney disease. www.translationalres.com/article/S193...
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Infinity Bio Inc @infinitybioinc.bsky.social · 11/11/2025
Diagnosing TB in children is a persistent challenge, as sputum-based tests are often ineffective. A new study used advanced plasma proteomics to identify a non-sputum-based biosignature for TB. The identified signatures meet WHO accuracy guidelines for a pediatric TB diagnostic. Read: rdcu.be/eOtzp
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Infinity Bio Inc @infinitybioinc.bsky.social · 04/11/2025
Diagnosing Lyme disease in the nervous system is slow & often requires an invasive spinal tap. A new study in Nature Communications used proteomics & machine learning to identify a diagnostic protein signature in plasma, crucial progress toward a less invasive test. www.nature.com/articles/s41...
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Infinity Bio Inc @infinitybioinc.bsky.social · 03/11/2025
Infinity Bio, Inc. is excited to join the LoCITT trial, powering advanced antibody reactome profiling to uncover key immune signatures & improve long COVID treatment. Proud to partner with Scripps Research for remote scientific progress. #LongCovid #LoCITT #AntibodyProfiling #Immunology
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Infinity Bio Inc @infinitybioinc.bsky.social · 28/10/2025
A study by Ruberto et al. profiled immune responses to HERV-W retrovirus proteins in Multiple Sclerosis patients. The findings suggest pHERV-W could be a valuable biomarker for predicting MS disease progression. www.frontiersin.org/journals/imm... #MultipleSclerosis #Immunology #InfectiousDisease
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Infinity Bio Inc @infinitybioinc.bsky.social · 21/10/2025
A groundbreaking study in Science creates a pan-disease blood atlas using proteomic 'fingerprints.' Analyzing 8262 individuals, they identified signatures for 59 diseases, found common biological themes, & developed a model that predicted lung cancer years before diagnosis. #Proteomics #Biomarkers
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Infinity Bio Inc @infinitybioinc.bsky.social · 14/10/2025
For our "Cohort of the Week," we are celebrating a study by Parodis and colleagues that tackles the challenge of diagnosing Systemic Lupus Erythematosus (SLE). Read the full paper: ard.eular.org/article/S000... #Lupus #SLE #Autoimmune #Biomarkers #Diagnostics
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Infinity Bio Inc @infinitybioinc.bsky.social · 07/10/2025
Immune responses to common viruses may lower dementia risk. Older adults with higher antibodies to HCoV-OC43 showed better cognition and brain health, with IGDCC4 identified as a promising target for neurodegeneration prevention. www.science.org/doi/10.1126/... #Neuroscience #Alzheimers #Immunology
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Infinity Bio Inc @infinitybioinc.bsky.social · 30/09/2025
his week, we are inspired by groundbreaking research from the IMPACC study, published in JCI. In their paper, “A multi-omics recovery factor predicts long COVID in the IMPACC study,” Read here: www.jci.org/articles/vie... #LongCOVID #LC #MultiOmics #Biomarkers #PrecisionMedicine #IMPACC
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Infinity Bio Inc @infinitybioinc.bsky.social · 18/09/2025
Our "Cohort of the Week" is a study on Lupus Nephritis (LN). Researchers used immunophenotyping to find distinct immune signatures in patients that traditional methods missed, linking them to treatment outcomes. A major step toward personalized medicine for LN. Read here: www.jci.org/articles/vie...
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Infinity Bio Inc @infinitybioinc.bsky.social · 16/09/2025
Thrilled to announce our Early Access Grant winners: Dr. Jakob Kreye (Charité), Dr. Sergio Poli (Brigham & Women’s Hospital), & Dr. Aubree Gordon (University of Michigan). Supporting their research in autoimmune, infectious, & neurological autoimmune disorders with cutting-edge antibody profiling.
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Infinity Bio Inc @infinitybioinc.bsky.social · 16/09/2025
Webinar TOMORROW! 🧬 “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Register here: www.labroots.com/ms/webinar/i... #Webinar #Immunology #AntibodyProfiling #PrecisionMedicine #InfinityBio #BiomedicalResearch
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Infinity Bio Inc @infinitybioinc.bsky.social · 12/09/2025
Countdown: Just a few days till the Sep 17 webinar! Hear from Katy Shaw-Saliba (Infinity Bio), Linda Kusner (GWU), Jessica Lasky-Su (Brigham/Harvard). Register: www.labroots.com/ms/webinar/i... #Webinar #Immunology #AntibodyProfiling #PrecisionMedicine #InfinityBio #BiomedicalResearch
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Infinity Bio Inc @infinitybioinc.bsky.social · 09/09/2025
Explore antibody profiling’s future! Sep 17 webinar: “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Sign up: www.labroots.com/ms/webinar/i... #Immunology #AntibodyProfiling #PrecisionMedicine #BiomedicalResearch
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Infinity Bio Inc @infinitybioinc.bsky.social · 08/09/2025
A new study by @thushan-desilva.bsky.social @alexjkeeley.bsky.social & colleagues provides a framework for future Streptococcus pyogenes (Strep A) vaccine development by examining the natural acquisition of humoral immunity! www.nature.com/articles/s41... #Microbiology #Pathogen #VaccineDevelopment
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Infinity Bio Inc @infinitybioinc.bsky.social · 03/09/2025
Just 2 weeks left! Join us Sep 17 for “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Register here : www.labroots.com/ms/webinar/i...
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Infinity Bio Inc @infinitybioinc.bsky.social · 02/09/2025
New Cohort of the Week! A groundbreaking proteogenomic study links major depressive disorder (MDD) to an increased risk for Alzheimer's disease and related dementia (ADRD). Full paper: nature.com/articles/s44... #Neuroscience #Proteomics #ADRD #Dementia #MentalHealth #Omics
nature.com
Proteogenomic signature of Alzheimer’s disease and related dementia risk in individuals with major depressive disorder - Nature Mental Health
This study investigates biological mechanisms connecting major depressive disorder to Alzheimer’s disease risk, identifying six key proteins and establishing a proteomic risk score with strong predict...
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Infinity Bio Inc @infinitybioinc.bsky.social · 27/08/2025
New Cohort of the Week! 🧠 A fascinating study from Stanford University used proteomics & GWAS to investigate the brain barrier system's role in aging & neurodegeneration. Read the full paper: www.nature.com/articles/s41... #Neuroscience #Proteomics #GWAS #BrainHealth #Omics
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