Infinity Bio Inc @infinitybioinc.bsky.social · 08/09/2026Cohort of the Week! von Stemann et al. mapped the genetics of anti-cytokine autoantibodies to cancer protection and metabolic risk. Seromic profiling adds the critical environmental layer, offering powerful multi-omic insights into autoimmunity. rdcu.be/b4nyEn1C5Cha 010
Infinity Bio Inc @infinitybioinc.bsky.social · 26/08/2026New Cohort of the Week! Bellomo et al. prove a simple blood draw can differentiate AD, DLB & FTD using plasma #Proteomics. Combining this with antibody reactomics offers key multi-omic insights into the systemic immune dialogue driving #Neurodegeneration. rdcu.be/fAFt0 000
Infinity Bio Inc @infinitybioinc.bsky.social · 18/08/2026Are circulating proteins static fingerprints or dynamic state markers? New Nat Comms data shows they're both. Antibody reactomics adds this same depth to longitudinal cohorts, capturing lifelong immune memory alongside dynamic responses to new encounters. rdcu.be/fzmKA #Proteomics #AgingResearch 020
Infinity Bio Inc @infinitybioinc.bsky.social · 13/08/2026Infinity Bio's Cohort of the Week shows systemic autoantibodies mirror neurodegeneration in AD, PD & MS. Broadly profiling self, viral & environmental reactivities unlocks system-wide biomarkers. doi.org/10.1016/j.is... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 04/08/2026For our Cohort of the Week, a landmark Cell study shows biological baselines aren't fixed. Layering #antibody responses to 37 microbial antigens over deep #MultiOmics gave unique insight into how geographic exposure history drives biological aging. doi.org/10.1016/j.ce... 111
Infinity Bio Inc @infinitybioinc.bsky.social · 14/07/2026How does a lifetime of environmental exposures shape how we age? By adding antibody #Reactomics to plasma #Proteomics, we can map immune history to see how past infections contribute to #CellularAging and chronic disease. Potentially transformational. doi.org/10.1038/s415...doi.orgPlasma proteomic signatures of cellular aging predict human disease - Nature MedicineThe biological age of individual cell types can be evaluated using plasma proteomics, revealing diverse aging profiles across more than 40 cell types and links between the accelerated aging of specifi... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 23/06/2026A landmark study in Cell tracks proteomic signals to predict lung cancer 5+ years early. Want the full picture? Adding Infinity Bio’s antibody reactomics uncovers the precise infectious & environmental triggers contributing to the inflammatory response tracked by proteomics analysis. 000
Infinity Bio Inc @infinitybioinc.bsky.social · 16/06/2026New research in Cell Reports Medicine identifies specific gut species linked to Type 2 Diabetes risk. But an important question remains: does the host's immune response actively prevent or allow this microbial colonization? doi.org/10.1016/j.xc... Antibody reactomics can help solve this mystery. 010
Infinity Bio Inc @infinitybioinc.bsky.social · 02/06/2026By mapping proteomes across 5 major cohorts, a new Nature Aging study shows how APOE2 & APOE4 shape Alzheimer’s through entirely different pathways. Multi-omic profiling is unlocking hidden disease mechanisms. What omic layers are your cohort missing? rdcu.be/fkVs9 000
Infinity Bio Inc @infinitybioinc.bsky.social · 26/05/2026A landmark study on the new HHGP-HK Asian cohort revealed that standard health scores like PhenoAge fall short outside European populations. Large, diverse cohorts are critical to uncovering true global disease associations and validating biomarkers for everyone. #PrecisionMedicine 000
Infinity Bio Inc @infinitybioinc.bsky.social · 19/05/2026Large, diverse cohorts are vital for #PrecisionMedicine. "Matching" gut #Microbiome fingerprints across 674 geographical diverse #Melanoma patients creates accurate treatment outcome predictions. These microbial markers provide a durable benchmark for #Immunotherapy success. doi.org/10.1016/j.ce... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 12/05/2026Large diverse cohorts are the engine of #PrecisionMedicine New research using the #UCLAATLAS Biobank proves that ancestry-diverse genomic data uncovers novel disease associations, such as previously unreported risk loci. What other health critical ancestral differences await discovery? 000
Infinity Bio Inc @infinitybioinc.bsky.social · 21/04/2026New study in Nature shows #ImmuneAgeing starts early with T cell reprogramming and GATA3 activity. Adding antibody reactome profiling to these cohorts can reveal the extrinsic viral and environmental triggers of #Aging —a vital layer for the #MultiOmics stack. rdcu.be/fcrJT #HumanHealth 010
Infinity Bio Inc @infinitybioinc.bsky.social · 14/04/2026A new #HumanImmuneHealthAtlas published in Nature reveals that #ImmuneAgeing is a non-linear process starting earlier than we thought. By mapping these molecular transitions, we can better tailor vaccines and therapies to biological age, not just the clock. rdcu.be/fcrJT #Immunology #SystemsBiology 010
Infinity Bio Inc @infinitybioinc.bsky.social · 07/04/2026A new @cellcellpress.bsky.social study of 2,279 brain samples reveals deep molecular diversity in #Neurodegeneration. By mapping #Proteomics & PTMs, we move closer to #PrecisionMedicine and improved stratification between seemingly similar neurodegenerative diseases. www.cell.com/cell/fulltex... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 31/03/2026New research in @natmed.nature.com reveals IgG1 producing #Bcells are key to cancer #immunotherapy success. Data from 2k+ patients show these cells coordinate with T-cells to drive anti-tumor immunity. A shift toward humoral-cellular strategies could transform outcomes. rdcu.be/e90xdrdcu.beHumoral IgG1 responses to tumor antigens underpin clinical outcomes in immune checkpoint blockadeNature Medicine - Transcriptomic and clinical data analyses from multiple cohorts of patients with cancer receiving immunotherapy find that PD-1 blockade potentiates tumor-specific IgG1 plasma cell... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 24/03/2026New study from #LifelinesNEXT cohort: a map of 31k+ gut viruses in mother-infant pairs. Key findings: vaginal birth & breastfeeding drive viral diversity, linked to future allergy risk. Large-scale longitudinal measurements generate unique findings for human health. doi.org/10.64898/202... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 18/03/2026Thrilled to welcome Brian McKelligon as the new CEO of Infinity Bio! Brian's leadership will accelerate the reach of our #MIPSA technology and the inSIGHTs it delivers to researchers worldwide. Welcome to the team, Brian! #InfinityBio #AntibodyReactomics www.businesswire.com/news/home/20...businesswire.com 000
Infinity Bio Inc @infinitybioinc.bsky.social · 17/03/2026#MultipleSclerosis progression insights via #proteomic profiling: New study on MS reveals anti-viral response as a continuous disease driver, implicating #EBV infection beyond just a trigger. Highlights include sex-specific pathways for injury, repair & resilience. rdcu.be/e7ZWe #MSResearch 031
Infinity Bio Inc @infinitybioinc.bsky.social · 13/03/2026Infinity Bio's Katy Shaw-Saliba & Ben Larman just published a new study screening 85 Ig batches against 283,000+ viral peptides, uncovering pandemic-driven immune shifts & autoantibody changes. Discoveries like this begin with decoding the antibody reactome. doi.org/10.1002/eji....doi.orgViral Immunity in Immunoglobulin Products: Global Immunity Debt and Autoimmunity in the Postpandemic EraImmunoglobulin products derived from pooled global plasma reflect population-level antiviral immunity. Analysis of batches from 2017 to 2023 reveals pandemic-driven shifts in viral antibody profiles ... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 13/03/2026Researchers identified proteomic markers for #LymphoidCancer risk up to 10yrs before diagnosis. This large-scale discovery reveals how early molecular signatures like sCD23 can drive risk stratification & #EarlyDetection rdcu.be/e6GBZ%E2%80%8B #Proteomics #PrecisionMedicine #Biomarkers #Lymphoma 001
Infinity Bio Inc @infinitybioinc.bsky.social · 03/03/2026New research in #SjogrensDisease uses salivary & serum #Proteomics to link biomarkers with #HLA alleles and autoantibodies. Large-scale, multi-omic analysis like this reveals a dynamic immune record, paving the way for high-resolution patient stratification. doi.org/10.1016/j.ar... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 24/02/2026Groundbreaking study in @natmetabolism.nature.com uses #MultiOmics to reveal #genes & #proteins causal to #T2D. With 85% of effects tissue-specific, large-scale profiling across ancestries is key to unlocking #global therapeutic targets. rdcu.be/e4zRC #PrecisionMedicine #TranslationalResearch 000
Infinity Bio Inc @infinitybioinc.bsky.social · 17/02/2026New Cohort of the Week from @nataging.nature.com! By analyzing nearly 1,000 human CSF samples, researchers mapped thousands of protein changes linked to #BrainAging and AD. #Proteomics on large human cohorts set the foundation for CNS markers of an aging brain. pmc.ncbi.nlm.nih.gov/articles/PMC... 000
Infinity Bio Inc @infinitybioinc.bsky.social · 10/02/2026A new study in @natcomms.nature.com re-analyzed WGS data from ~750k individuals to find viral "dark matter". By mapping viral reads, researchers linked persistent #EBV to #chronicdiseases like Lupus and Dementia. Large-scale omics are key to unlocking new disease #biomarkers Article: rdcu.be/e2cAt 001
Infinity Bio Inc @infinitybioinc.bsky.social · 27/01/2026New study in @natcomms.nature.com: A 29-protein blood signature predicts #cancer in patients with vague symptoms. Crucially, it distinguishes malignancy from #autoimmune & infectious diseases. A vital triage tool to prioritize life-saving diagnostics. #PrecisionMedicine Read: rdcu.be/eZ6bE 010
Infinity Bio Inc @infinitybioinc.bsky.social · 20/01/2026A new study leverages a well characterized infant cohort to explore our #microbiome & immune health. Researchers analyzed 647 infants in the #COPSAC cohort & found environmental exposure (daycare, siblings) reduced anellovirus abundance, consistent with immune "training." #Virome #ImmuneSystem 030
Infinity Bio Inc @infinitybioinc.bsky.social · 13/01/2026New Nature Medicine research maps blood #biomarkers related to #aging. By analyzing 54 biomarkers related to accumulated disease over 15 years, researchers identified key "biological signatures" predictive of aging. Large cohort studies are transformative for predictive health! #geroscience 000
Infinity Bio Inc @infinitybioinc.bsky.social · 06/01/2026New research reveals a link between Epstein-Barr virus (EBV) & Primary Sclerosing Cholangitis. Systematic #immuneprofiling shows that #PSC associated T & B cells target #EBV, suggesting it may drive pathogenesis. www.nature.com/articles/s41... #Omics #LiverDisease #Autoimmunity #Bcell #Tcell 010
Infinity Bio Inc @infinitybioinc.bsky.social · 16/12/2025Great news in neurodegeneration research! Hok-A-Hin et al. used large-scale CSF proteomics on a multicenter cohort to identify new biomarkers for Frontotemporal Dementia (FTD). Importantly, identified biomarker panels distinguish FTD from Alzheimer’s in presymptomatic cases. lnkd.in/eatVVT6K 010
Infinity Bio Inc @infinitybioinc.bsky.social · 10/12/2025New research sheds light on the food allergy. Gill, et al. found that children with food sensitization have gE B-cells that are less mature, more diverse. This was abrogated (stopped) by having a pet dog in the first year of life, supporting the hygiene hypothesis. doi.org/10.1111/all.... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 02/12/2025Cohort of the Week: Exciting new study on a large cohort of Guillain-Barré syndrome patients. Glycolipid complex auto-antibody patterns cluster into groups linked to clinical features. A step towards personalized medicine for the diagnosis, prognosis, & treatment of GBS. doi.org/10.1093/brai... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 18/11/2025Lupus (SLE) symptoms are notoriously varied. New research groups patients into 6 'serological subsets' based on autoantibody profiles. Links to genetic factors (NCF2, HLA) help predict specific outcomes, like blood disorders or lower rates of kidney disease. www.translationalres.com/article/S193... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 11/11/2025Diagnosing TB in children is a persistent challenge, as sputum-based tests are often ineffective. A new study used advanced plasma proteomics to identify a non-sputum-based biosignature for TB. The identified signatures meet WHO accuracy guidelines for a pediatric TB diagnostic. Read: rdcu.be/eOtzp 031
Infinity Bio Inc @infinitybioinc.bsky.social · 04/11/2025Diagnosing Lyme disease in the nervous system is slow & often requires an invasive spinal tap. A new study in Nature Communications used proteomics & machine learning to identify a diagnostic protein signature in plasma, crucial progress toward a less invasive test. www.nature.com/articles/s41... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 03/11/2025Infinity Bio, Inc. is excited to join the LoCITT trial, powering advanced antibody reactome profiling to uncover key immune signatures & improve long COVID treatment. Proud to partner with Scripps Research for remote scientific progress. #LongCovid #LoCITT #AntibodyProfiling #Immunology 020
Infinity Bio Inc @infinitybioinc.bsky.social · 28/10/2025A study by Ruberto et al. profiled immune responses to HERV-W retrovirus proteins in Multiple Sclerosis patients. The findings suggest pHERV-W could be a valuable biomarker for predicting MS disease progression. www.frontiersin.org/journals/imm... #MultipleSclerosis #Immunology #InfectiousDisease 011
Infinity Bio Inc @infinitybioinc.bsky.social · 21/10/2025A groundbreaking study in Science creates a pan-disease blood atlas using proteomic 'fingerprints.' Analyzing 8262 individuals, they identified signatures for 59 diseases, found common biological themes, & developed a model that predicted lung cancer years before diagnosis. #Proteomics #Biomarkers 000
Infinity Bio Inc @infinitybioinc.bsky.social · 14/10/2025For our "Cohort of the Week," we are celebrating a study by Parodis and colleagues that tackles the challenge of diagnosing Systemic Lupus Erythematosus (SLE). Read the full paper: ard.eular.org/article/S000... #Lupus #SLE #Autoimmune #Biomarkers #Diagnostics 010
Infinity Bio Inc @infinitybioinc.bsky.social · 07/10/2025Immune responses to common viruses may lower dementia risk. Older adults with higher antibodies to HCoV-OC43 showed better cognition and brain health, with IGDCC4 identified as a promising target for neurodegeneration prevention. www.science.org/doi/10.1126/... #Neuroscience #Alzheimers #Immunology 010
Infinity Bio Inc @infinitybioinc.bsky.social · 30/09/2025his week, we are inspired by groundbreaking research from the IMPACC study, published in JCI. In their paper, “A multi-omics recovery factor predicts long COVID in the IMPACC study,” Read here: www.jci.org/articles/vie... #LongCOVID #LC #MultiOmics #Biomarkers #PrecisionMedicine #IMPACC 021
Infinity Bio Inc @infinitybioinc.bsky.social · 18/09/2025Our "Cohort of the Week" is a study on Lupus Nephritis (LN). Researchers used immunophenotyping to find distinct immune signatures in patients that traditional methods missed, linking them to treatment outcomes. A major step toward personalized medicine for LN. Read here: www.jci.org/articles/vie... 020
Infinity Bio Inc @infinitybioinc.bsky.social · 16/09/2025Thrilled to announce our Early Access Grant winners: Dr. Jakob Kreye (Charité), Dr. Sergio Poli (Brigham & Women’s Hospital), & Dr. Aubree Gordon (University of Michigan). Supporting their research in autoimmune, infectious, & neurological autoimmune disorders with cutting-edge antibody profiling. 010
Infinity Bio Inc @infinitybioinc.bsky.social · 16/09/2025Webinar TOMORROW! 🧬 “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Register here: www.labroots.com/ms/webinar/i... #Webinar #Immunology #AntibodyProfiling #PrecisionMedicine #InfinityBio #BiomedicalResearch 010
Infinity Bio Inc @infinitybioinc.bsky.social · 12/09/2025Countdown: Just a few days till the Sep 17 webinar! Hear from Katy Shaw-Saliba (Infinity Bio), Linda Kusner (GWU), Jessica Lasky-Su (Brigham/Harvard). Register: www.labroots.com/ms/webinar/i... #Webinar #Immunology #AntibodyProfiling #PrecisionMedicine #InfinityBio #BiomedicalResearch 010
Infinity Bio Inc @infinitybioinc.bsky.social · 09/09/2025Explore antibody profiling’s future! Sep 17 webinar: “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Sign up: www.labroots.com/ms/webinar/i... #Immunology #AntibodyProfiling #PrecisionMedicine #BiomedicalResearch 010
Infinity Bio Inc @infinitybioinc.bsky.social · 08/09/2025A new study by @thushan-desilva.bsky.social @alexjkeeley.bsky.social & colleagues provides a framework for future Streptococcus pyogenes (Strep A) vaccine development by examining the natural acquisition of humoral immunity! www.nature.com/articles/s41... #Microbiology #Pathogen #VaccineDevelopment 173
Infinity Bio Inc @infinitybioinc.bsky.social · 03/09/2025Just 2 weeks left! Join us Sep 17 for “How Measuring The Reactivities Of Circulating Antibodies Through Reactome Profiling Can Provide Novel Insights Into Human Health.” Register here : www.labroots.com/ms/webinar/i... 010
Infinity Bio Inc @infinitybioinc.bsky.social · 02/09/2025New Cohort of the Week! A groundbreaking proteogenomic study links major depressive disorder (MDD) to an increased risk for Alzheimer's disease and related dementia (ADRD). Full paper: nature.com/articles/s44... #Neuroscience #Proteomics #ADRD #Dementia #MentalHealth #Omicsnature.comProteogenomic signature of Alzheimer’s disease and related dementia risk in individuals with major depressive disorder - Nature Mental HealthThis study investigates biological mechanisms connecting major depressive disorder to Alzheimer’s disease risk, identifying six key proteins and establishing a proteomic risk score with strong predict... 020
Infinity Bio Inc @infinitybioinc.bsky.social · 27/08/2025New Cohort of the Week! 🧠 A fascinating study from Stanford University used proteomics & GWAS to investigate the brain barrier system's role in aging & neurodegeneration. Read the full paper: www.nature.com/articles/s41... #Neuroscience #Proteomics #GWAS #BrainHealth #Omics 030