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João Ferreira Fernandes

@immjoao.bsky.social

Postdoc @ucl.ac.uk | Visiting Scientist @crick.ac.uk Formerly DPhil @ox.ac.uk @imm.ox.ac.uk

João Ferreira Fernandes @immjoao.bsky.social · 04/04/2025

From the ɑβ- and γδ-TCR to important checkpoint inhibition targets like PD-1 and CTLA-4, this review gives focus to the important previous contributions from @imm.ox.ac.uk and collaborators to this field. @ox.ac.uk @rdmoxford.bsky.social @imm.ox.ac.uk (with @sumanasharma.bsky.social)

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João Ferreira Fernandes @immjoao.bsky.social · 04/04/2025

Happy to share that our review on the structural biology of T-cell surface proteins is out in Immunological Reviews. Here we describe the ways in which crystal structures and cryo-EM have informed our understanding of receptor behaviour and T-cell biology. onlinelibrary.wiley.com/doi/full/10....

onlinelibrary.wiley.com

The Structural Biology of T‐Cell Antigen Detection at Close Contacts

T cells physically interrogate their targets using tiny membrane protrusions called microvilli, forming junctions ~400 nm in diameter and ~ 15 nm deep, referred to as “close contacts”. These contacts...

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Reposted by João Ferreira Fernandes

MRC Weatherall Institute of Molecular Medicine @imm.ox.ac.uk · 14/03/2025

Congratulations to Dr Sumana Sharma (@sumanasharma.bsky.social), who has won a Wellcome Career Development Award for her research investigating receptors in T cells 🎉 Read more: www.imm.ox.ac.uk/news/wellcom... @rdmoxford.bsky.social | @wellcometrust.bsky.social

imm.ox.ac.uk

Wellcome Career Development Award For Sumana Sharma

Dr Sumana Sharma has won a Wellcome Career Development Award for her research investigating receptors in T cells.

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