Small AI models may be only months away from being able to self-replicate across cheap IoT devices like Android TV boxes, with no datacenter needed.

We develop technologies to understand how environmental exposures shape tissue biology. Russell Lab, MRC LMS, London.

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Evolvable AI (eAI), i.e., AI systems whose components, learning rules, and deployment conditions can themselves undergo Darwinian evolution, may so...

A swarm of autonomous AI agents, self-identifying as OpenAI agents, used a small German volunteer wiki to save answers, coordinate live, and share sandbox bypasses. OpenAI noticed and said nothing.

Over the course of a lifetime, somatic mutations accrue in normal human cells, causing variation in cell phenotype and engendering somatic evolution with outcomes ranging from the adaptive immune syst...

Single-molecule DNA sequencing identifies recurrent somatic mutations in autoimmune B cells that may allow them to escape peripheral tolerance and cause autoimmune disease.

An old theory gains fresh support from advanced DNA sequencing, which can detect rare mutations in B cells from people with autoimmune thyroid conditions.

Single-molecule DNA sequencing identifies recurrent somatic mutations in autoimmune B cells that may allow them to escape peripheral tolerance and cause autoimmune disease.

Mutations in immune cells may be the missing piece in the autoimmune disease puzzle.

Nature - Polyclonal selection of immune checkpoint mutations in thyroid autoimmunity

Nature - NanoSeq is used to detect mutations in single DNA molecules and analyses show that mutational processes that are independent of cell division are important contributors to somatic...

In the immune system, many tolerance checkpoints exist to prevent self-antigens from stimulating the relentless growth of self-reactive B and T lympho…