Thrilled to share that my first paper in the lab of @drmichaelway.bsky.social is now published in @narjournal.bsky.social!
We showed that Topoisomerase 2α and 2β have opposing roles in vaccinia virus replication, one promoting and the other restricting it 👇🏼
doi.org/10.1093/nar/...
doi.org
Nonredundant roles of topoisomerase 2α and 2β in the cytosolic replication of vaccinia virus
Abstract. Vaccinia virus is a large enveloped DNA virus, which, like all poxviruses, replicates in the cytoplasm of infected cells. Vaccinia was historical