Burnout/ˈbərnˌaʊt/noun. Exhaustion of physical or emotional strength or motivation usually as a result of prolonged stress or frustrationverb. To cause to fail, wear out, or become exhausted, especial...

Introduction: Target volumes for irradiation remain ill-defined for head and neck squamous cell cancer of unknown primary (HNSCCUP). The aim of this study was to compare two commonly used radiotherapy...

Grade 2 meningiomas often recur after surgery and radiation therapy. However, large, in-depth failure analyses are lacking, limiting the potential to refine radiation therapy. We report a pattern of f...

Brain radionecrosis (RN) is a significant late toxicity of radiation therapy, yet its progression remains challenging to predict due to patient-specific factors. This study develops a mechanistic mode...

Physicians are highly resilient people who can thrive under tremendously difficult situations. We are practiced at working diligently for long-term goals that require delaying gratification. Both natu...

Patient education is demonstrated to reduce patient anxiety, facilitate shared decision-making, and improve treatment outcomes. This scoping review characterizes the state of radiation therapy patient...

Consolidating accumulated knowledge into a single qualitative or quantitative analysis allows researchers to summarize large bodies of information succinctly, providing clinicians with an assessment o...

Private equity (PE) acquisitions of physician practices have seen a significant increase in recent years. The surge in PE acquisitions raises concerns about market consolidation, affordability, and qu...

Workforce Roles and Impact of Adaptive Radiation Therapy

To demonstrate safety and feasibility of 2-fraction stereotactic body radiotherapy (SBRT) for prostate cancer.

Radiation therapy is essential in both curative and palliative treatments for most cancers. However, traditional radiation therapy workflows using computed tomography (CT) simulation-based planning an...

The mevalonate (MVA) pathway plays a critical role in cholesterol biosynthesis, protein prenylation, and metabolic reprogramming, all of which contribute to cancer progression and therapy resistance. ...

Abdominal computed tomography (CT)-guided online adaptive stereotactic ablative radiotherapy (SABR) treatments can be complicated by bowel gas artifact. We investigated whether prolonged patient supin...

Chemotherapy (CT) is the standard of care for patients presenting with unresectable advanced gallbladder carcinoma (GBC) but their prognosis remains poor. The value of consolidation CT and radiation t...

Transitioning from Radiation Oncology (RO) training to independent practice is often challenging. Understanding resident attitudes related to program satisfaction and comfort with treatment modalities...

There is growing interest in reirradiation (reRT) for new or recurrent malignancies in previously irradiated regions.1-25 Historically, reRT to the same or an adjacent site has been used relatively sp...

A 75-year-old man enters your clinic with a new diagnosis of high-risk localized prostate cancer. You suggest to him a state-of-the-art treatment plan: radiation therapy to the prostate and lymph node...

I was recently informed that I won a contest that I did not actually enter. A Twitter poll was organized through @Radiation Nation inspired by Sue Yom, the new editor of the journal, asking, “What do ...

Radiation necrosis (RN) is a dose-limiting toxicity of stereotactic radiosurgery (SRS) for brain metastases. Oral corticosteroids are not optimal for long-term management, given multiple side effects....

Electronic patient-reported outcome measures (ePROMs) are collected routinely at an oncology institution throughout patients’ treatment and follow-up. Clinicians from the institution's head and neck t...

Oligometastatic Head and Neck Cancer – Rationale for Upfront SABR

Optimal management of oligoprogressive prostate cancer whilst on androgen receptor pathway inhibitors (ARPi) is not known. The **** trial tests the ro…

Standard therapy for breast cancer after breast-conserving surgery is radiation therapy (RT) plus hormone therapy (HT). For patients with a low-risk of recurrence, there is an interest in deescalating...

BRCAness: A Lever for Chemoradiation Enhancement