Reposted by Hongbo Sun
🆕 New paper out with Jean-Luc Imler and Rune Hartmann in EMBO journal.
We dissect mechanisms of antiviral immunity and how STING is activated by FADD and DREDD during viral infection in Drosophila melanogaster. link.springer.com/article/10.1...
link.springer.com
FADD is recruited to activated STING oligomers to initiate caspase-mediated NF-κB activation in Drosophila melanogaster - The EMBO Journal
STING is an evolutionarily conserved key regulator of innate immunity. In the model organism Drosophila melanogaster, STING activates the NF-κB-like transcription factor Relish, initially characterize...
