iiinova — where your digital self keeps evolving

Melissa Harrison Lab

@harrisonflylab.bsky.social

95 followers 78 following 7 posts

How transcription is regulated to drive development harrisonlab.bmolchem.wisc.edu

Posts Replies Media

Melissa Harrison Lab @harrisonflylab.bsky.social · 11/03/2026

Beautiful story @nmaziak.bsky.social. Really fun collaboration with @vaquerizasjm.bsky.social. Love that this started through a casual conversation during my time in UK. When posed a challenge we were eager to see if we could deplete GAF and Zld together. So pleased that it worked. 🎉

020

Melissa Harrison Lab @harrisonflylab.bsky.social · 22/10/2025

Proud of the lab for helping teach kids and adults about Drosophila research and the importance of funding foundational science at the Wisconsin Science Festival today. Couldn't ask for a more engaged and enthusiastic group.

040

Melissa Harrison Lab @harrisonflylab.bsky.social · 30/09/2025

So excited for this conference. Cant beat great science in a beautiful location. Don’t miss out!

020

Melissa Harrison Lab @harrisonflylab.bsky.social · 29/08/2025

A vital resource. Please support.

010

Reposted by Melissa Harrison Lab

The Lewis Lab @peterlewislab.bsky.social · 24/07/2025

We are excited to share our new preprint demonstrating that nucleic acid interactions with SUZ12 constrain PRC2 activity, establishing a kinetic buffer essential for targeted gene silencing and revealing vulnerabilities in diffuse midline gliomas. www.biorxiv.org/content/10.1...

14819

Reposted by Melissa Harrison Lab

Babis Galouzis @babisgalouzis.bsky.social · 10/06/2025

Check our latest with Yacine Kherdjemil and @eileen-furlong.bsky.social and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression. www.cell.com/molecular-ce...

cell.com

Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation

Chip/Ldb1 is a crucial cofactor regulating enhancer function and chromatin interactions. Using optogenetics, Galouzis, Kherdjemil et al. show that Chip is only essential during zygotic genome activati...

1154

Melissa Harrison Lab @harrisonflylab.bsky.social · 30/05/2025

Lucky to have the Lewis lab right next door. This collaboration really took advantage of our shred interests and unique strengths. Also a fearless grad student- Sam Krabbenhoft.

010

Melissa Harrison Lab @harrisonflylab.bsky.social · 30/05/2025

Nice to see this highly collaborative effort pay off and to see our paper out! Love that all the tools in Drosophila allowed us to get at mechanistic details of this conserved process.

030

Reposted by Melissa Harrison Lab

eric lai @lucksmith.bsky.social · 16/05/2025

www.nytimes.com/2025/05/16/s...

nytimes.com

9 Federally Funded Scientific Breakthroughs That Changed Everything

024

Melissa Harrison Lab @harrisonflylab.bsky.social · 01/04/2025

Amazing examples of the fundamental principles that can be learned by studying developing organisms. Great job!

020