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Melissa Harrison Lab

@harrisonflylab.bsky.social
95 followers 78 following 7 posts

How transcription is regulated to drive development harrisonlab.bmolchem.wisc.edu

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Melissa Harrison Lab @harrisonflylab.bsky.social · 22/10/2025
Proud of the lab for helping teach kids and adults about Drosophila research and the importance of funding foundational science at the Wisconsin Science Festival today. Couldn't ask for a more engaged and enthusiastic group.
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Melissa Harrison Lab @harrisonflylab.bsky.social · 29/08/2025
A vital resource. Please support.
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Reposted by Melissa Harrison Lab
The Lewis Lab @peterlewislab.bsky.social · 24/07/2025
We are excited to share our new preprint demonstrating that nucleic acid interactions with SUZ12 constrain PRC2 activity, establishing a kinetic buffer essential for targeted gene silencing and revealing vulnerabilities in diffuse midline gliomas. www.biorxiv.org/content/10.1...
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Reposted by Melissa Harrison Lab
Babis Galouzis @babisgalouzis.bsky.social · 10/06/2025
Check our latest with Yacine Kherdjemil and @eileen-furlong.bsky.social and our colleagues, where we show Chip (Ldb1) is essential only at a narrow window of embryogenesis overlapping ZGA. It functionally and physically bridges CBP to Zelda to regulate gene expression. www.cell.com/molecular-ce...
cell.com
Chip (Ldb1) is a putative cofactor of Zelda forming a functional bridge to CBP during zygotic genome activation
Chip/Ldb1 is a crucial cofactor regulating enhancer function and chromatin interactions. Using optogenetics, Galouzis, Kherdjemil et al. show that Chip is only essential during zygotic genome activati...
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Reposted by Melissa Harrison Lab
eric lai @lucksmith.bsky.social · 16/05/2025
www.nytimes.com/2025/05/16/s...
nytimes.com
9 Federally Funded Scientific Breakthroughs That Changed Everything
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