Reposted by Hannah TrostSusan Kilgas @susankilgas.bsky.social · 26/11/2025A reminder to register for the 2026 GRS meeting taking place from Feb 28-Mar 1 in Ventura, CA! 033
Reposted by Hannah TrostMetztli Cisneros-Aguirre @cisnerosmetztli.bsky.social · 05/11/2025🧬Register for the GRS on DNA Damage, Mutation & Cancer🧬 Feb 28–Mar 1 2026, Ventura CA Accepting abstracts for oral presentations! 📍 Apply here 👉 grc.org/dna-damage-mutation-and-cancer-grs-conference/2026 (www.grc.org/dna-damage-m...) #DNADamage #GRC#GRS #CallForAbstractsgrc.org2026 DNA Damage, Mutation and Cancer (GRS) Seminar GRCThe 2026 Gordon Research Seminar on DNA Damage, Mutation and Cancer (GRS) will be held in Ventura, California. Apply today to reserve your spot. 0106
Reposted by Hannah TrostbioRxiv Molecular Biology @biorxiv-molbio.bsky.social · 19/09/2025L1 insertion intermediates recombine with one another or with DNA breaks to form genome rearrangements www.biorxiv.org/content/10.1101/202… 033
Reposted by Hannah TrostCarlos Mendez-Dorantes, PhD @carlosmendezphd.bsky.social · 19/09/2025Check out our pre-print: We show that L1 insertion intermediates can recombine with one another or with DNA breaks to form genome rearrangements, highlighting the risk of L1 retrotransposition generating substrates for aberrant recombination and genome instability. www.biorxiv.org/content/10.1...biorxiv.orgL1 insertion intermediates recombine with one another or with DNA breaks to form genome rearrangementsLINE-1 retrotransposition is common in human cancers and rearrangements at insertion sites can contribute to cancer-driving oncogene amplifications and promote genome instability. However, the mechani... 066
Hannah Trost @hannahtrost.bsky.social · 06/02/2025Annual H&M botanical gardens photo at the GRC @cisnerosmetztli.bsky.social 041
Reposted by Hannah TrostJustin Ling @biochem-ling.bsky.social · 05/02/2025Very happy to have had the opportunity to give my poster at the GRC this year! Had a lot of great discussions and questions. 052
Reposted by Hannah TrostNick Pannunzio @pannunziolab.bsky.social · 28/01/2025Have they completely lost their mind? A freeze to all federal spending. Just a blanket statement with no details? As if no one is depending on this funding. Upending 95% of the government and economy to get rid of the 5% that triggers them on their revenge tour www.politico.com/news/2025/01...politico.comTrump administration orders sweeping freeze of federal aidIn a two-page memo, the Office of Management and Budget ordered all federal agencies to temporarily suspend payments. 051
Reposted by Hannah TrostIndivisible ❌👑 @indivisible.org · 25/01/2025Instead of lowering prices, the Trump Administration is disrupting the work of researchers who are studying life-saving medicines and treatments.cnn.comScientists at NIH can’t purchase supplies for their studies after Trump administration pauses outside communications | CNNScientists at the National Institutes of Health have been told the communications pause announced by the Trump Administration earlier this week includes a pause on all purchasing, including supplies f... 15441191
Reposted by Hannah TrostNick Pannunzio @pannunziolab.bsky.social · 26/01/2025Now more than ever it's important for communities that support science to band together. The future of cancer health disparity research in the US is in jeopardy. If you're interested in connecting to other disparities researchers on bsky, I can add you to this starter pack 💪🧬🩸💉🔬 go.bsky.app/HyLFqvg 02210
Reposted by Hannah TrostCarlos Mendez-Dorantes, PhD @carlosmendezphd.bsky.social · 19/12/2024Check out our latest pre-print: we show that the LINE-1 retrotransposon is a potent source of chromosomal rearrangements and instability in addition to insertional mutagenesis using shotgun and long-read WGS. www.biorxiv.org/content/10.1...biorxiv.orgChromosomal rearrangements and instability caused by the LINE-1 retrotransposon 1175
Reposted by Hannah TrostbioRxivpreprint @biorxivpreprint.bsky.social · 18/12/2024Chromosomal rearrangements and instability caused by the LINE-1 retrotransposon www.biorxiv.org/content/10.1101/202… 022
Hannah Trost @hannahtrost.bsky.social · 02/12/2024So excited to see the second piece of my PhD project out 🥳 www.sciencedirect.com/science/arti...sciencedirect.comFunctions of PMS2 and MLH1 important for regulation of divergent repeat-mediated deletionsRepeat-mediated deletions (RMDs) are a type of deletion rearrangement that utilizes two repetitive elements to bridge a DNA double-strand break (DSB) … 290
Reposted by Hannah TrostJStark lab @jstarklab.bsky.social · 29/11/2024New study from the lab @hannahtrost.bsky.social Functions of PMS2 and MLH1 important for regulation of divergent repea... www.sciencedirect.com/science/arti...sciencedirect.comFunctions of PMS2 and MLH1 important for regulation of divergent repeat-mediated deletionsRepeat-mediated deletions (RMDs) are a type of deletion rearrangement that utilizes two repetitive elements to bridge a DNA double-strand break (DSB) … 1195
Hannah Trost @hannahtrost.bsky.social · 18/11/2024Come join us in Ventura at the 2025 @GordonConf GRS on Mammalian DNA Repair on Feb 1-2! Spots are filling up fast!! Talks selected from submitted abstracts grc.org/mammalian-dn...grc.org2025 Mammalian DNA Repair (GRS) Seminar GRCThe 2025 Gordon Research Seminar on Mammalian DNA Repair (GRS) will be held in Ventura, California. Apply today to reserve your spot. 010
Reposted by Hannah TrostAndrew Blackford @andrewblackford.bsky.social · 13/11/2024Hi BlueSky! It's great to be here. Here's a handy Starter Pack of DNA repair & genome stability groups that I found so far go.bsky.app/NvFWKvL 105521