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Hanna Brunner

@hannabrunner.bsky.social
72 followers 94 following 0 posts

PhD student in the Haselbach Lab at IMP Vienna

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Reposted by Hanna Brunner
Juan Carlos De la Concepcion @delaconcepcionjc.bsky.social · 30/01/2026
Please share! My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th! uni-tuebingen.de/universitaet...
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Reposted by Hanna Brunner
Lorenz Grundmann @lgrundmann.bsky.social · 27/01/2026
Check out our new paper in @natcomms.nature.com .com where we used #cryoEM together with biochemical and mutational analyses investigated the cotranslational protein folding by Ssb in yeast. Publication: doi.org/10.1038/s41467-025-67685-6 Check below for the cryoEM centric feed. 👇
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Reposted by Hanna Brunner
Pauli Group (posts by Andi Pauli) @pauligroup.bsky.social · 13/12/2024
The life of each of us began when a sperm and an egg came together. But what happens at a molecular level? Our latest work in Cell led by @vdeneke.bsky.social & Andreas Blaha reveals a conserved fertilization complex that bridges sperm and egg in vertebrates! (1/11) www.cell.com/cell/fulltex...
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Reposted by Hanna Brunner
Haselbach Lab @haselbachlab.bsky.social · 06/12/2024
The second of our two new preprints addresses the question of how proteasomes can be kept dormant for instance in oocytes. This study was spearheaded by first author Sascha Amann. biorxiv.org/cgi/content/... (1/6)🧵
biorxiv.org
PITHD1: An Endogenous Inhibitor of the 26S Proteasome During Cellular Dormancy
Cellular dormancy represents a state of regulated growth arrest essential for diverse biological processes, from reproduction to cancer progression. While mechanisms controlling protein synthesis in d...
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Reposted by Hanna Brunner
Haselbach Lab @haselbachlab.bsky.social · 05/12/2024
We are very excited to share our recent preprint on the nuclear import mechanism of the proteasome, driven by the multivalent adaptor AKIRIN2! www.biorxiv.org/content/10.1... 🧵 1/6
biorxiv.org
A multivalent adaptor mechanism drives the nuclear import of proteasomes
Nuclear protein homeostasis, including the turnover of transcription factors, critically depends on nuclear proteasomes. After each cell division, proteasomes need to be re-imported into the newly for...
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