Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...

How does the brain learn to predict rewards? In this issue of Nature Neuroscience, Qian, Burrell et al. show that understanding how dopamine guides learning requires knowledge of how animals interpret...

During foraging with threat–reward conflicts in mice, dopamine modulates two competing neuron types in the striatum for flexible threat coping, from initial threat avoidance to eventual overcoming of ...

The mechanisms by which the brain replays neural activity sequences remain unknown. Recording from large ensembles of hippocampal place cells in freely behaving rats, we observed that replay content i...