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Hamperl Lab

@hamperllab.bsky.social
173 followers 157 following 11 posts

We are professional DNA traffic controllers and study how transcription and replication are moving smoothly (most of the time).

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Hamperl Lab @hamperllab.bsky.social · 19/08/2026
We’re so excited for this coming event! 🎉
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Sidrit Uruci (Sid) @sidrituruci.bsky.social · 17/05/2026
Small contribution to the eternal match happening inside every cell: in the red corner, replication. In the blue corner, transcription. Both convinced they own the genome. Another amazing collaboration with @hamperllab.bsky.social and @luijsterburglab.bsky.social lnkd.in/ey9tH7YF
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Hamperl Lab @hamperllab.bsky.social · 24/06/2026
Secure your spot today! 📣
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Helmholtz Munich @helmholtzmunich.bsky.social · 08/04/2026
Summer School on Chromatin Biology 2026 at #HelmholtzMunich 🧬 📢 Application Deadline Extended to April 18, 2026. 👉 Further information on the programme & application process: lnkd.in/dN-xXmEr #abcam #summerschool #phd
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Hamperl Lab @hamperllab.bsky.social · 04/08/2025
Our latest research is online in the @biorxivpreprint.bsky.social! 🧬🎉 🔎 We have developed a novel, single-cell real-time approach to monitor R-loop generated TRCs, and we have shown R-loop-mediated, replisome-controlled transcription repression. www.biorxiv.org/cgi/content/...
biorxiv.org
Replisome progression regulates R-loop mediated transcriptional repression
Maintaining cellular proliferation necessitates the synchronized activity of diverse molecular machineries operating in parallel on the genome. Wide-spread transcription and R-loop formation can inter...
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Hamperl Lab @hamperllab.bsky.social · 04/08/2025
Such a nice review for one of our latest research works!
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Hamperl Lab @hamperllab.bsky.social · 24/03/2025
Two days of science, international cooking, and breathtaking hikes in the Bavarian Alps—our lab retreat in Mittenwald had it all! Great discussions, great food, and even better company.
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Epigenetics at Helmholtz Munich @epihmgu.bsky.social · 18/03/2025
🚨Paper Alert! 👏 Big congrats to @marcelwerner.bsky.social, ManuelTrauner & rest of @hamperllab.bsky.social team for this brilliant work! 🧬 Check out their amazing research diving into how #TRCs and DOT1L impact genome stability. A must-read 🧵 for #transcription, #replication & #epigenetics fans👇!
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Antonio Scialdone @antonio-scialdone.bsky.social · 12/02/2025
How can we improve gene regulatory network inference from noisy scRNA-seq data? Our new review in @molsystbiol.org explores the latest methods integrating prior knowledge to enhance reliability. Plus, some suggestions on how to improve benchmarking! www.embopress.org/doi/full/10....
embopress.org
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data | Molecular Systems Biology
EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
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Hamperl Lab @hamperllab.bsky.social · 20/02/2025
Proud to share our latest publication in @narjournal.bsky.social! A fantastic team effort led by @marcelwerner.bsky.social and Manuel T., where we explore the chromatin dynamics at transcription-replication conflicts (TRC) sites and their impact on genome stability using a novel TRC reporter system.
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Epigenetics at Helmholtz Munich @epihmgu.bsky.social · 15/01/2025
Best first bsky post posible 4us: 2025 INTERNSHIP CALL IS NOW OPEN! Ready for an adventure this summer? Join our 2025 #Epigenetics #SummerInternship at Helmholtz Munich! Dive into AI, stem cells, nutrition and cutting-edge research, while gaining hands-on experience. Apply now! 👉 bit.ly/40g1BWL
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