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Guigó Lab

@guigolab.bsky.social
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Roderic Guigó's Computational Biology of RNA Processing Lab @crg.eu genome.crg.cat

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Max Stammnitz @maxstammnitz.bsky.social · 23/02/2026
Wonderful to have David Duffy with us last week! Lots of new biodiversity genomics and eDNA approaches in the making ... 🧬🐢🌦️ @crg.eu @prbb.org @ufresearch.bsky.social
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Centre de Regulació Genòmica (CRG) @crg.eu · 18/02/2026
Fa 25 anys, el Projecte Genoma Humà sortia als informatius… i avui TV3 ens recorda aquell moment amb una joia d’arxiu: la entrevista a en Roderic i en Pep quan es va publicar a Nature i Science.
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Guigó Lab @guigolab.bsky.social · 17/02/2026
🧬 Aquest any es compleixen 25 anys d’un moment clau per a la ciència: la publicació de la primera seqüència del genoma humà. Un projecte col·laboratiu a escala mundial amb la participació dels investigadors Pep Abril i @rodericguigo.bsky.social @crg.eu www.3cat.cat/3cat/25-anys...
3cat.cat
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Genetics UB @geneticsub.bsky.social · 17/02/2026
Fa 25 anys de la publicació de la primera seqüència del genoma humà, un esforç internacional que va tenir aportació catalana, amb els investigadors Pep Abril @geneticsub.bsky.social i Roderic Guigó @crg.eu Podeu consultar la notícia completa al 3cat: www.3cat.cat/3cat/telenot...
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Centre de Regulació Genòmica (CRG) @crg.eu · 16/02/2026
Exactly 25 years ago, @rodericguigo.bsky.social and his PhD student published the first draft of the human genome in Science. The Catalan researchers were the only two from all Spain that took part. Here they are reflecting on the huge scientific feat: www.crg.eu/en/news/25-y...
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Guigó Lab @guigolab.bsky.social · 13/02/2026
This weekend marks the 25th anniversary of the publication of the human genome. Read @rodericguigo.bsky.social memories of the event here: www.crg.eu/en/news/25-y...
crg.eu
Centre for Genomic Regulation Website
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Guigó Lab @guigolab.bsky.social · 10/02/2026
Pep Abril y @rodericguigo.bsky.social dentro del mayor proyecto de biomedicina denla historia hace un cuarto de siglo elpais.com/ciencia/2026...
elpais.com
Los dos españoles dentro del mayor proyecto de biomedicina de la historia: “Con Trump, no sería posible”
Pep Abril y Roderic Guigó compusieron el primer mapa del genoma humano hace un cuarto de siglo. El megaproyecto internacional no ha traído aún una esperada revolución en medicina, pero ha cambiado la ...
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Guigó Lab @guigolab.bsky.social · 05/02/2026
🔬🧬 Nou #Recerclip publicat! La recerca del @crg.eu, presentat per l'Andreu Juanola. Podeu descobrir diversos projectes, com ara #PyriSentinel 🏔️ @hannahbenisty.bsky.social youtu.be/MQv6-InbREs @crg.eu @prbb.org @cerca.cat @bist.eu #POCTEFA #Interreg
youtu.be
Nou Recerclip. La llista de reproducció del cos: l'Andreu Juanola va al Centre de Regulació Genòmica
YouTube video by Recerca i Universitats
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Centre de Regulació Genòmica (CRG) @crg.eu · 13/01/2026
Conocer la variabilidad genética de todo el mundo acaba beneficiando a todo el mundo. Lo cuenta Michele Catanzaro en El Periódico después de que un estudio coliderado por @rodericguigo.bsky.social descubrió y cuantificó las lagunas en los mapas genéticos.
elperiodico.com
El sesgo europeo en los mapas genéticos entorpece la investigación biomédica
Los mapas de expresión de los genes están dominados por datos de individuos de ascendencia europea y presentan importantes lagunas de información sobre el resto del mundo
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Catalan Initiative for the Earth Biogenome Project @catbiogenoma.bsky.social · 13/01/2026
@rodericguigo.bsky.social (@crg.eu) i @tmarquesbonet.bsky.social (@ibe-barcelona.bsky.social - @cnag-eu.bsky.social) membres de la CBP participaran en la commemoració dels 25 anys del Projecte Genoma Humà aportant una mirada experta sobre genòmica, biodiversitat i futur de la recerca 👇
cnag.eu
El Proyecto Genoma Humano: 25 años después | CNAG, Centro Nacional de Análisis Genómico
"El Proyecto Genoma Humano: 25 años después" is a commemorative event marking the scientific milestone that has transformed science and medicine worldwide.
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Guigó Lab @guigolab.bsky.social · 05/12/2025
Thrilled to share! 🧬🌍 Our 800M+ long-read RNA-seq dataset from 8 diverse populations reveals big gaps in gene annotations for non-European transcripts. Let’s build global inclusive annotations. @bsc-cns.bsky.social @crg.eu @melelab.bsky.social www.nature.com/articles/s41...
nature.com
Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation - Nature Communications
Current human gene annotations are predominantly based on individuals of European ancestry. Here, the authors use long-read RNA sequencing across diverse human populations to reveal ancestry-specific ...
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Centre de Regulació Genòmica (CRG) @crg.eu · 03/12/2025
Human gene maps contain major blind spots that leaves out a vast majority of the world's biological diversity, according to a new study led by the CRG's @rodericguigo.bsky.social with @bsc-cns.bsky.social. The researchers uncovered tens of thousands of new transcripts and entirely new genes.
nature.com
Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation - Nature Communications
Current human gene annotations are predominantly based on individuals of European ancestry. Here, the authors use long-read RNA sequencing across diverse human populations to reveal ancestry-specific ...
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Melé Lab @melelab.bsky.social · 04/12/2025
📣 Yesterday our study uncovering the ancestry bias in gene annotations was finally published in @natcomms.nature.com! www.nature.com/articles/s41... If you work in human genetics or transcriptomics, do not miss our tweetorial!👇 @guigolab.bsky.social @bsc-cns.bsky.social @crg.eu
nature.com
Long-read transcriptomics of a diverse human cohort reveals ancestry bias in gene annotation - Nature Communications
Current human gene annotations are predominantly based on individuals of European ancestry. Here, the authors use long-read RNA sequencing across diverse human populations to reveal ancestry-specific ...
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Centre de Regulació Genòmica (CRG) @crg.eu · 25/11/2025
Our annual PhD call is closing at the end of this week on 30 November. If you're interested in carrying out world-class scientific research in Barcelona, you still have a few days left to submit your application! www.crg.eu/en/content/t...
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Guigó Lab @guigolab.bsky.social · 23/10/2025
📢🎓Join our lab at @crg.eu through the International PhD Programme! We’re looking for a student motivated to uncover the rules of genome architecture through bioinformatics and machine learning 🧬💻 🔵Apply here: www.crg.eu/en/content/t...
crg.eu
Centre for Genomic Regulation Website
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Guigó Lab @guigolab.bsky.social · 04/10/2025
Avui hem obert les portes de la nostra recerca als visitants de l’ #OpenPRBB 🔬🪰🧬 Sempre amb molta il·lusió! @crg.eu @prbb.org
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Arnau Sebé-Pedrós @arnausebe.bsky.social · 24/09/2025
Happy to share the Biodiversity Cell Atlas white paper, out today in @nature.com. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life. www.nature.com/articles/s41...
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Guigó Lab @guigolab.bsky.social · 22/09/2025
🌍✨ Master’s project in our Lab @crg.eu 🌱🧬 Help build the Biodiversity Long-Read Transcriptomic Catalogue @ebpgenome.bsky.social with @pacbio.bsky.social & @nanoporetech.com 💻 Python/R, Linux, seq data 💶 600€/mo + travel 📩 fabio.zanarello@crg.eu / roderic.guigo@crg.eu ℹ️ www.crg.eu/en/content/t...
crg.eu
Centre for Genomic Regulation Website
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Guigó Lab @guigolab.bsky.social · 28/07/2025
🚨 We are hiring a Postdoc @crg.eu! 🧬 
Within the EU-funded #PrecisionTox project. We are developing computational methods to predict toxicity by integrating RNA-seq data from humans and model species 🪱🪰🐸🐠. The project will help replace animal testing. 🔗 Apply now: recruitment.crg.eu/content/jobs...
recruitment.crg.eu
Post-Doctoral Researcher for Precision Tox | CRG Online Recruitment Portal
The Centre for Genomic Regulation (CRG) is an international biomedical research institute of excellence, based in Barcelona, Spain, with more than 400 scientists from 44 countries. The CRG is composed by an interdisciplinary, motivated and creative scientific team which is supported both by a flexible and efficient administration and by high-end and innovative technologies.
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Guigó Lab @guigolab.bsky.social · 24/07/2025
🎉 We’ve earned Bronze LEAF Accreditation for our efforts to make lab work more sustainable @crg.eu! By joining @ucl.ac.uk Laboratory Efficiency Assessment Framework, we are committed to improving efficiency and reducing our environmental impact. 🌱🔬
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Guigó Lab @guigolab.bsky.social · 18/07/2025
🎓 Huge congrats to our two @bist.eu Master’s students, Igor Trujnara and @rebeccawallis.bsky.social who successfully defended their theses this week! 🧬💻Igor explored Large Language Models for genome annotation, while Rebecca investigated microbial biodiversity in Pyrenean lakes🏔️. @crg.eu @upf.edu
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Guigó Lab @guigolab.bsky.social · 16/07/2025
🚴🏻🚴🏻‍♀️🚴🏻‍♂️ Read about Ana, Fabio & Nadja’s journey to the LongTREC Summer School in Norwich! #LongTREC #ScienceOnTheMove #SustainableScience #Bioinformatics #ScienceLife
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Guigó Lab @guigolab.bsky.social · 16/07/2025
Great to see our PhD student Fabio Zanarello sharing his work yesterday at LongTREC summer school! #LongReadsTranscriptomics #LongTREC #GenomeAnnotation #Bioinformatics #EarthBioGenomeProject @crg.eu
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Ana Conesa @anaconesa.bsky.social · 12/07/2025
We made it!!!! València-London by train. London-Norwich by bike!!!
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LongTREC @longtrec.bsky.social · 11/07/2025
First journey done! 🌟 Our amazing cyclists arrived safely in Cambridge — still smiling! 😄🚴‍♀️ More than the ride: sustainability, team spirit & pushing limits. They’re recharging now… and ready for the next leg! #LongCyclingForScience #TeamSpirit @anaconesa.bsky.social #LeadingByExample
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LongTREC @longtrec.bsky.social · 12/07/2025
Not everyone can or wants to cycle for 2–3 days, but we can all take a moment to ask ourselves: 💡 “How much am I impacting the planet with this trip?” 💡 “What can I do to reduce that impact?” @anaconesa.bsky.social #LongCyclingForScience #SustainableScience #LongReadsTranscriptomics
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Guigó Lab @guigolab.bsky.social · 11/07/2025
🚴 From @crg.eu to the roads of Europe, our PhD student Fabio and the #LongTREC team are combining cutting-edge science with sustainable travel. Now in London, and heading next to Cambridge! #LongCyclingForScience
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Guigó Lab @guigolab.bsky.social · 11/07/2025
🚴‍♂️🌍 Excited to see our PhD student Fabio Zanarello featured in the #LongTREC video series! 👏 Don’t miss the video and learn more about #LongTREC #LongReadsTranscriptomics and #LongCyclingForScience. #SustainableScience #Bioinformatics #PhDLife @crg.eu
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Ana Conesa @anaconesa.bsky.social · 10/07/2025
This is going to be so much fun!!! Do not miss our #LongCyclingForSciene adventure! from Valencia to Norwich by train & bike, posting about science and bcsustainability @pacbio.bsky.social @nanoporetech.com @iscb.bsky.social @csic.es @hitseq.bsky.social @bcbhubcsic.bsky.social @sebibc.bsky.social
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Guigó Lab @guigolab.bsky.social · 02/07/2025
📊 RNA localization matters for gene regulation. We present a method to estimate transcript distributions between nucleus & cytosol using nuclear, cytosolic and whole-cell RNAseq. 🔵🧬 doi.org/10.1093/narg... @crg.eu @rodericguigo.bsky.social
doi.org
Studying relative RNA localization from nucleus to the cytosol
Abstract. The precise coordination of important biological processes, such as differentiation and development, relies heavily on the regulation of gene exp
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Pau Clavell-Revelles @pclavell.bsky.social · 30/05/2025
I am so happy to learn that I won the Early Career Award for an outstanding presentation at the ESHG!! Thanks to @melelab.bsky.social, @guigolab.bsky.social and to my awesome colleagues that also attended the conference for their support @rubenchazarra.bsky.social @ramirezjmiguel.bsky.social
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Guigó Lab @guigolab.bsky.social · 14/05/2025
Our lab had dual presence at #BoG25 @cshlmeetings.bsky.social! 🧬 Silvia González-López spoke on chromatin dynamics & transcriptional regulation. 🌍 @fairlie.bsky.social presented ancestry-aware gene annotations — a @guigolab.bsky.social × @melelab.bsky.social collab: www.biorxiv.org/content/10.1...
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Guigó Lab @guigolab.bsky.social · 12/05/2025
Exciting day in the lab, congratulations to Dr. Ntasis on successfully defending! 🎓🥳
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Rebecca Wallis D @rebeccawallis.bsky.social · 08/05/2025
Had a great time at the Computational Symposium- such a valuable opportunity to connect with colleagues, hear about exciting projects, and share progress on my master’s research! Presenting my work on the Pyrenean Lake microbiome has been invaluable for gathering feedback and ideas for my analysis 🙂
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Guigó Lab @guigolab.bsky.social · 30/04/2025
This week, we had a great time attending the 19th Computational Genomics Symposium at @prbb.org, a very nice opportunity to catch up with colleagues 💻🧬☀️ @crg.eu
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UCSC Genome Browser @genomebrowser.bsky.social · 25/03/2025
A new hub has been added to the Public Hubs listing, EPIration - an atlas of candidate enhancer-gene interactions in human tissues and cell lines. View this hub using the following URL: genome.ucsc.edu/cgi-... We want to thank the @guigolab.bsky.social for making this data available.
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Guigó Lab @guigolab.bsky.social · 22/03/2025
🚀 Our new paper is out! The BioGenome Portal: an open-source customizable platform for managing biodiversity genomics data 🧬🌍 doi.org/10.1093/narg... @crg.eu @rodericguigo.bsky.social #genomics #biodiversity
academic.oup.com
The BioGenome Portal: a web-based platform for biodiversity genomics data management
Abstract. Biodiversity genomics projects are underway with the aim of sequencing the genomes of all eukaryotic species on Earth. Here we describe the BioGe
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Marta Melé @martamele.bsky.social · 20/03/2025
This has been a fantastic collaboration with @guigolab.bsky.social and led by @pclavell.bsky.social & @fairlie.bsky.social where we show something we suspected for some time: human gene annotations are European-biased, read this thread to know more about this work @bsc-cns.bsky.social @crg.eu
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Pau Clavell-Revelles @pclavell.bsky.social · 20/03/2025
I never thought that I would wear again the lab coat 🥼 but I did it to sequence RNA with @nanoporetech.com at @guigolab.bsky.social . Thanks to @scarbonells.bsky.social , Carme and Zighi for their great teachings and patience in the wetlab. They definitely have solutions for everything!
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Melé Lab @melelab.bsky.social · 20/03/2025
Do you work in 💫human genetics💫? Have you ever worried about what’s inside your gene annotation GTF⁉️ WELL, YOU SHOULD! 😱 Especially when studying a genetically diverse 🌍 cohort! 🔴We discover that gene annotations are European-biased 👉 impacting downstream analyses! Don't miss this thread🧵⬇️ 1/13
biorxiv.org
Long-read transcriptomics of a diverse human cohort reveals widespread ancestry bias in gene annotation
Accurate gene annotations are fundamental for interpreting genetic variation, cellular function, and disease mechanisms. However, current human gene annotations are largely derived from transcriptomic...
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Winona Oliveros @oliveroswinona.bsky.social · 18/03/2025
I am SO EXCITED about this! An incredible amount of work from two brilliant people. I believe a bluetorial is on the way, stay tuned! 💜 @fairlie.bsky.social @pclavell.bsky.social @melelab.bsky.social @guigolab.bsky.social
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Guigó Lab @guigolab.bsky.social · 11/03/2025
Hi Bluesky! Excited to be here! Last week we had our yearly retreat in the mountains, enjoying nature, games, and discussions 🏔️🧬😊
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