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Grubb Lab

@grubblabneuro.bsky.social
515 followers 513 following 29 posts

We’re interested in the function, development and regeneration of the nervous system, especially when those processes are shaped by neuronal plasticity. Based at the Centre for Developmental Neurobiology @ King's College London

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Grubb Lab @grubblabneuro.bsky.social · 28/07/2026
Registration now open for our AIS meeting, organised with @royalsociety.org in Edinburgh, 7th-8th December 2026! royalsociety.org/science-even...
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Ana Dorrego Rivas @adorrego.bsky.social · 02/10/2025
As promised, and committing to the core open science values of our lab, here's the updated preprint. More data, more supplementary figures, stronger conclusions. 'Strikingly different neurotransmitter release strategies in dopaminergic subclasses' www.biorxiv.org/content/10.1...
biorxiv.org
Strikingly different neurotransmitter release strategies in dopaminergic subclasses
Neuronal function is intimately tied to axodendritic polarity. Neurotransmitter release, for example, is usually the role of the axon. There are widespread exceptions to this rule, however, including ...
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Nivedita Sarveswaran @neuroniv.bsky.social · 03/10/2025
🔜The 1st Congenital Insensitivity to Pain conference is now 1 week away! Please join us (in-person/online) if you're interested in how painlessness is inherited, different phenotypic presentations and molecular mechanisms - the developmental PRDM12-TrkA-NGF axis and Nav channels among them.
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bioRxiv Neuroscience @biorxiv-neursci.bsky.social · 02/10/2025
Human brain organoids record the passage of time over multiple years in culture www.biorxiv.org/content/10.1101/202…
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Grubb Lab @grubblabneuro.bsky.social · 18/09/2025
Haoming won best poster at last year’s retreat, and now Ana takes home best talk! The team is on a roll!
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Ana Dorrego Rivas @adorrego.bsky.social · 16/09/2025
On the way back to London after 2 amazing days sharing science in the CDN department retreat - and look what I got!
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Ana Dorrego Rivas @adorrego.bsky.social · 17/09/2025
And, of course, congrats to the other awardees! The science in this department is top notch, and it shows! 🧠
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Grubb Lab @grubblabneuro.bsky.social · 14/07/2025
The paper is out in journal format at EJN! We thank the reviewers for their insightful comments, and how they shaped the final form of this story. Check it out here: onlinelibrary.wiley.com/doi/10.1111/... As usual, it's open access! We're getting the data ready for sharing very soon 👀🧠🧪
onlinelibrary.wiley.com
Functional Maturation and Experience‐Dependent Plasticity in Adult‐Born Olfactory Bulb Dopaminergic Neurons
Adult-born dopaminergic neurons in the mouse olfactory bulb are almost functionally mature at 5 weeks of cellular age. More immature adult-born dopaminergic cells do not have elevated functional ...
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Emily Winson-Bushby @emily-winson.bsky.social · 08/07/2025
This was so much fun today! So grateful for the opportunity to talk about my work, & to get to return to my beloved PDN!!
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Grubb Lab @grubblabneuro.bsky.social · 08/07/2025
We're on our way to UKSN! Our very own @emily-winson.bsky.social is speaking today in the physiology session, and will bring some fresh-out-of-the oven data! 👀🧠
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Elisa Galliano @elisagalliano.bsky.social · 16/06/2025
Olfaction geeks, come to Cambridge next month for a 30yrs old cross-disciplinary smell chat from philosophy to clinics to circuits 🧠👃 Headliner @dattalab.bsky.social on his lab's brand new olfactory maps study Networking lunches, fancy College dinner, student discount, plenty of coffee. Go register!
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The Mental Elf @thementalelf.bsky.social · 14/05/2025
Prof @grubblabneuro.bsky.social adds to the compelling case set by previous speakers: Open Science = Better Science (for the community and for YOU!) ✅ Data sharing improves accessibility, reproducibility & collaboration ❌ But it’s often effortful & time-consuming #IoPPNFestival
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Institute of Psychiatry, Psychology & Neuroscience @kingsioppn.bsky.social · 14/05/2025
‪Open Research Award winner Professor @grubblabneuro.bsky.social speaks on the benefits of making science as open as possible, and tips and tricks to make the process smoother. #IoPPNFestival‬
Professor Matthew Grubb
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Ana Dorrego Rivas @adorrego.bsky.social · 13/05/2025
The master @grubblabneuro.bsky.social at the rig! Thanks so much @victoria-swi.bsky.social for showing us how to patch OSNs, and for unveiling my absolute lack of brain plasticity when it comes to using an ephys setup that is not mine 😆
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Grubb Lab @grubblabneuro.bsky.social · 10/05/2025
Matt will be speaking about data sharing and open science practices at this year’s @kingsioppn.bsky.social IoPPN Research Festival! www.kcl.ac.uk/events/ioppn...
kcl.ac.uk
IoPPN Research Festival 2025 - Bridging disciplines, brain to behaviour
An annual showcase of exciting and innovative research celebrating academic success across the IoPPN.
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The Mental Elf @thementalelf.bsky.social · 09/05/2025
We are IN-PERSON in London next week for the #IoPPNfestival, sharing transformative research from @kingsioppn.bsky.social Join @saakshikakar.bsky.social using the #IoPPNfestival hashtag from 2 pm on Wednesday, 14th May! THREAD
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The Mental Elf @thementalelf.bsky.social · 09/05/2025
Watch this space for more on the #IoPPNfestival and share your thoughts! @julietfoster.bsky.social @devinterhune.bsky.social @uwedrescher11.bsky.social @sianoram.bsky.social @grubblabneuro.bsky.social @denklab.bsky.social
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Grubb Lab @grubblabneuro.bsky.social · 09/05/2025
Eventually, the office’s door will become a Faraday cage ⚡️🤪
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Ana Dorrego Rivas @adorrego.bsky.social · 10/04/2025
@neuroversepod.bsky.social is one of my fav podcasts. It's super exciting to have been at the other side in this episode! I talk about how I'm navigating my postdoc and academic life, and some tips for PhDs who are planning their next steps. Link below 👇🏼 🧠🔬🧪 open.spotify.com/episode/1677...
open.spotify.com
96. Tools for Looking into the Brain: How to Make the Most of Your Postdoc (with Dr Ana Dorrego-Rivas)
Neuroverse · Episode
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Ana Dorrego Rivas @adorrego.bsky.social · 27/02/2025
Hey #NeuroSky, has anyone used a MAP2 antibody that successfully labels the soma on mouse brain slices? We've tried one but it stains only the dendrites. Any advice will be useful! 🧠🧪
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Ana Dorrego Rivas @adorrego.bsky.social · 11/02/2025
Our paper is now in the shape of a reviewed preprint on eLife @elife.bsky.social, with the reviewers' comments on full display. We plan to address these in the upcoming weeks/months, but so far I'm a big fan of this publishing model! elifesciences.org/reviewed-pre...
elifesciences.org
Strikingly different neurotransmitter release strategies in dopaminergic subclasses
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Grubb Lab @grubblabneuro.bsky.social · 10/02/2025
Thank you everyone for coming to our data sharing workshop, we loved it all! The talks, the questions, the interactions, the snacks... We hope you learnt about open science practices as much as we did! 😊 À la prochaine!
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Ana Dorrego Rivas @adorrego.bsky.social · 10/02/2025
We’re starting! 🧠🧪
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Grubb Lab @grubblabneuro.bsky.social · 27/01/2025
There's still time to register for our data sharing workshop! Info and link below 👇🏻
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Centre for Developmental Neurobiology @devneuro.bsky.social · 22/01/2025
If you’re interested in finding out how to share your research data (and why it matters!), @grubblabneuro.bsky.social will be holding a free workshop on 10th February. See thread below👇 for more info and registration link!
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Grubb Lab @grubblabneuro.bsky.social · 20/01/2025
Ever wondered how to share research data but didn’t know where to start? Join us for an informal and open workshop where we’ll break down the how and why of data sharing.
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Ana Dorrego Rivas @adorrego.bsky.social · 11/01/2025
'Universities have warned of significant financial concerns as a result of frozen domestic tuition fees and a decline in overseas students following the policy changes.' www.standard.co.uk/news/politic...
standard.co.uk
Number of people applying for British work visas from abroad drops 43% in a year
The number of people applying for visas to work and study in the UK fell by nearly 400,000
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Intro to BN open textbook @introtobn.bsky.social · 08/01/2025
Spotlight: Ever noticed that food loses flavor when you have a cold. What's up with that? Your perception of flavor is not one sense. It is a mixing of taste, smell and chemosensation. Read about it in Ch8 Chemical Senses by Joe Zak & @jakesaunders.bsky.social tinyurl.com/itobnch8 #neuroscience
The left panel of this image shows the side view of a person’s face with a cup containing a beverage underneath the nose. The image shows how the aroma of the beverage passes through the nasal cavity. The right panel shows a detailed ultrastructure of the olfactory bulb. A textbox reads: Odorant molecules activate receptors in the cilia of olfactory sensory neurons. Olfactory sensory neuron axons cross into the olfactory bulb, synapsing on mitral cells in polysynaptic structures called glomeruli.
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Grubb Lab @grubblabneuro.bsky.social · 09/01/2025
Save the date! We're organising a workshop on Data Sharing on the 10th of February at Guy's Campus (KCL)! All you need to know to make your datasets open to the public + engaging in open science practices. More details to come soon — stay tuned!
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Grubb Lab @grubblabneuro.bsky.social · 07/01/2025
The link from the @devneuro.bsky.social site with the news of our award! devneuro.org/cdn/news-det...
devneuro.org
CDNCDN - news-detail
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Grubb Lab @grubblabneuro.bsky.social · 06/01/2025
We start 2025 with the best news! Our lab has been awarded the Open Research Award from the @kingsioppn.bsky.social ! 🥳 we are thankful to the past and current members of the lab who helped create and shape the open science culture of the team!
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INCF @incforg.bsky.social · 15/12/2024
Applications open to the University of Sussex Neuroscience's Sep 2025 PhD program, fully-funded, +UKRI rate stipend 🧠 📅 Apply by Jan 13 Research themes incl: - Sensory neuroscience - Neural circuits of behavior - Learning & memory - Neurodegeneration - Computational neuroscience & AI - & more!
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Grubb Lab @grubblabneuro.bsky.social · 14/12/2024
And we WON! First time ever for the lab, we won the 'Wildest Interpretation of the Theme' category! 😎
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Ana Dorrego Rivas @adorrego.bsky.social · 13/12/2024
CDN Christmas Party 2024!!! @grubblabneuro.bsky.social @devneuro.bsky.social
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Grubb Lab @grubblabneuro.bsky.social · 13/12/2024
It's #FluorescenceFriday! Here's a biocytin-filled neuron (cyan) + AIS staining (orange) by @adorrego.bsky.social 🧪🧠🔬
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Phoebe Reynolds @pheereynolds.bsky.social · 11/12/2024
I’m over the moon to have won the @britishneuro.bsky.social award for Public Engagement 2024 🥳✨🧠 Massive thanks to the panel! This is such an exciting recognition of public engagement work in neuroscience! @kingscollegelondon.bsky.social @devneuro.bsky.social
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Grubb Lab @grubblabneuro.bsky.social · 09/12/2024
Transcriptomic cell-type specificity of local cortical circuits www.cell.com/neuron/fullt...
cell.com
Transcriptomic cell-type specificity of local cortical circuits
Patiño et al. introduce single transcriptome assisted rabies tracing (START), a new technical approach combining transsynaptic neuronal circuit mapping with transcriptomic classification to achieve precise neuronal characterization. Using START, they identify novel local cortical circuit connectivity motifs between inhibitory neuron subtypes and layer-specific excitatory subclasses.
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Grubb Lab @grubblabneuro.bsky.social · 08/12/2024
Have you read Candida's preprint yet?
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Watanabe Lab @JHU @watanabelab.bsky.social · 02/12/2024
Excited to share our latest findings, now published @NatureNeuro www.nature.com/articles/s41... We found unmyelinated axons exhibit pearls-on-a-string morphology's due to their membrane mechanical properties. Threads will follow!
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Dan Jagger @auditorynerves.bsky.social · 02/12/2024
⭐ Word of the week: "nanopearling". ⭐ Is the "pearls-on-a-string" morphology in unmyelinated nerve fibres physiological or pathological? 🧪🧠 #neuroskyence www.nature.com/articles/s41...
nature.com
Membrane mechanics dictate axonal pearls-on-a-string morphology and function - Nature Neuroscience
Axons have always been assumed to be cylindrical. Using in silico modeling and cryopreservation of tissues, Griswold et al. demonstrate that unmyelinated axons of the mammalian central nervous system ...
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Grubb Lab @grubblabneuro.bsky.social · 29/11/2024
We have *another* preprint! This work was led by the amazing Candida Tufo, ex-PhD student in the lab. We show that adult-born dopaminergic cells in the olfactory bulb rapidly functionally resemble their pre-existing counterparts! Have a look at the preprint here: www.biorxiv.org/content/10.1...
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Johanna Joyce @johannajoyce.bsky.social · 25/11/2024
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️ So how can we ever achieve #gender #equality? We discuss various strategies in this #Cell Commentary #WomeninSTEM www.cell.com/cell/fulltex... 🧵 1/
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Siegenthaler Lab @siegenthalerlab.bsky.social · 30/11/2024
🧪 #Neuroscience
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Ana Dorrego Rivas @adorrego.bsky.social · 29/11/2024
Check out the latest paper from the lab, it’s now live on bioRxiv!
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Grubb Lab @grubblabneuro.bsky.social · 29/11/2024
We have *another* preprint! This work was led by the amazing Candida Tufo, ex-PhD student in the lab. We show that adult-born dopaminergic cells in the olfactory bulb rapidly functionally resemble their pre-existing counterparts! Have a look at the preprint here: www.biorxiv.org/content/10.1...
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Christophe 🔬 Leterrier @christlet.bsky.social · 28/11/2024
In Bordeaux? Come on Friday to a symposium on "Advanced imaging techniques to study the cytoskeleton" featuring Marina Mikhaylova, Francesca Pennacchietti, Nils Gauthier and I. Starts at 9h in the Bordeaux Biologie Santé building on the Carreire campus: www.bordeaux-neurocampus.fr/en/event/gpr...
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Moritz Engelhardt @moritzengelhardt.bsky.social · 15/11/2024
Seeing many new #olfaction researches on Bluesky, nice! I made a starter pack for researchers and groups studying the sense of smell or taste. If you want to get added let me know. go.bsky.app/xfXg9B
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Elisa Galliano @elisagalliano.bsky.social · 27/11/2024
📢👃Updated 𝗢𝗹𝗳𝗮𝗰𝘁𝗼𝗿𝘆 𝗦𝘁𝗮𝗿𝘁𝗲𝗿𝗣𝗮𝗰𝗸, thanks Moritz! May I encourge everyone to follow, retweet, and 𝙚𝙖𝙧𝙡𝙮 𝙘𝙖𝙧𝙚𝙚𝙧 𝙧𝙚𝙨𝙚𝙖𝙧𝙘𝙝𝙚𝙧𝙨 to request to be added? We want to connect with you and follow your work 😁 @achems.bsky.social #neuroskyence #olfaction
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UCL Neuroscience @uclnpp.bsky.social · 27/11/2024
Lets start with something exciting! Applications are now open to join our fantastic department as a group leader fellow! Come start your independent group at (in our opinion) the best neuroscience department! reach out here or @macaskillaf.bsky.social for more info! www.ucl.ac.uk/work-at-ucl/...
ucl.ac.uk
UCL – University College London
UCL is consistently ranked as one of the top ten universities in the world (QS World University Rankings 2010-2022) and is No.2 in the UK for research power (Research Excellence Framework 2021).
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