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Gonzalo Villanueva Martin

@gonzalovm.bsky.social
25 followers 38 following 8 posts

PhD in biomedicine. Computational genomics and transcriptomics postdoc. Postdoctoral researcher at the @bsci-lab.bsky.social

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Reposted by Gonzalo Villanueva Martin
Blood Stem Cell Identity Lab @bsci-lab.bsky.social · 05/08/2026
🛬 Welcome Gonzalo @gonzalovm.bsky.social to the lab! He joins us as a computational postdoc to investigate how blood stem cells remodel their transcriptome and epigenome across different tissue sources and during ex vivo culture. 🖥️🩸
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Reposted by Gonzalo Villanueva Martin
Maria Gutierrez-Arcelus @mariagtac.bsky.social · 31/07/2026
How do genetic #riskvariants translate into cellular dysfunction in #autoimmunedisease? Excited to share our latest preprint “Variant-to-function mapping in lupus links IL12A to the expansion of disease-associated B cells with a cytotoxic program” www.medrxiv.org/content/10.6...
medrxiv.org
Variant-to-function mapping in lupus links IL12A to the expansion of disease-associated B cells with a cytotoxic program
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by over 200 risk variants identified through genome-wide association studies. While the majority of these are non-codin...
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Gonzalo Villanueva Martin @gonzalovm.bsky.social · 03/08/2026
🚀A few weeks ago, I joined @bsci-lab.bsky.social It’s an amazing group advancing blood stem cell biology at @carrerasijc.bsky.social in Barcelona🩸 I’m thrilled to be back in Spain doing exciting science. Thanks to Vincenzo for this opportunity—I look forward to contributing to the lab’s research!
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Gonzalo Villanueva Martin @gonzalovm.bsky.social · 05/06/2026
🎓 Today is my last day at Boston Children’s Hospital and Harvard Medical School. Grateful for an incredible experience filled with great science, wonderful colleagues, and invaluable lessons. Thank you to @mariagtac.bsky.social and the Immunology Division 💙 🚀 On to new adventures! #Postdoc
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Gonzalo Villanueva Martin @gonzalovm.bsky.social · 19/03/2026
🧬 Excited to share our new preprint! We characterized CD4+ T cells in #SystemicSclerosis using #SingleCellRNAseq, revealing IFN-driven activation, Treg dysregulation, and Th2/Th17 expansion in disease. 📄 www.biorxiv.org/content/10.6... #scRNAseq #Immunology #SSc
biorxiv.org
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 30/10/2025
Sobre nuestro último estudio de metilación del ADN en arterias de pacientes de arteritis de células gigantes!! 👇🏼👇🏼
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Gonzalo Villanueva Martin @gonzalovm.bsky.social · 29/10/2025
#ACR2025 is over! Grateful for the chance to dive deep into rheumatology, present Liyoung Kim’s poster, and meet so many inspiring scientists. Thanks to Maria Gutierrez-Arcelus for the support! See you next time! 👋 #Rheumatology #Immunology #ACR
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Gonzalo Villanueva Martin @gonzalovm.bsky.social · 17/10/2025
Grateful for the chance to share my project in the poster session at #ASHG2025 in Boston and to learn from brilliant scientists. Thanks to everyone who stopped by and sparked great discussions! #Genetics #ASHG
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 02/10/2025
We’d like to know too… #graphicmedicine #rheumsky #medsky
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 28/08/2025
New paper just out (online first) in Arthritis & Rheumatology! 🎉 We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵 Read: doi.org/10.1002/art.... cc @ipblncsic.bsky.social
doi.org
Genome‐wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients
Objectives Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by ...
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Reposted by Gonzalo Villanueva Martin
Vitor Aguiar @vitoraguiar.bsky.social · 28/05/2025
I’m excited to share my latest work with Marcella Franco, @mariagtac.bsky.social, and an amazing team. We used multi-omics to dissect key pathways of B cell activation, exploring gene programs, splicing, cell fates, and disease heritability in activated B cells. www.medrxiv.org/content/10.1...
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 28/05/2025
Excited to share that our abstract for #EULAR was selected as one of the Top 10 Abstracts at EULAR 2025 by EMEUNET! 🙌🥰 Huge thanks to the committee, I’m truly honored! Hope to see you in Barcelona! #EMEUNET #EULAR2025
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 25/03/2025
If I had an habit of terribly procrastinating writing, I’d totally recommend this feature from @naturebiotech.bsky.social. But, you know, for other people www.nature.com/articles/s41...
nature.com
An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
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Reposted by Gonzalo Villanueva Martin
Max Planck Institute for Molecular Genetics @molgen.mpg.de · 07/03/2025
#StandUpForScience👩‍🔬👨‍🔬📢Scientists at the Max Planck Institute for Molecular Genetics in Berlin, including our managing director, show solidarity with our colleagues in the US who are protesting against the attacks of the current US administration. @standupforscience.bsky.social @maxplanck.de
Scientists standing in front of the Max Planck Institute for Molecular Genetics holding signs "#StandUpForScience"
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Reposted by Gonzalo Villanueva Martin
Andrés Trasado @andrestrasado.bsky.social · 04/03/2025
Inolvidables los diálogos que escribía Asimov
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Gonzalo Villanueva Martin @gonzalovm.bsky.social · 04/03/2025
🧬 New preprint by good friend @goboru.bsky.social! DNA methylation profiling in giant cell arteritis (GCA) reveals altered inflammatory & vascular pathways, plus exhausted T cells (SLAMF6, HAVCR2). New insights into GCA pathogenesis! 📄 Read more in: www.biorxiv.org/content/10.1... #Vasculitis #GCA
biorxiv.org
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Reposted by Gonzalo Villanueva Martin
Javi Martínez-López @javiml221098.bsky.social · 13/02/2025
A few years ago, we started a fun 'Plot of the Month' competition. Each member made a plot with their data and shared the code to learn ggplot2 together. At the end of the month, we’d vote for the best one, and the winner kept a cute trophy for the next month. It made plotting way more fun!
The plot of the month trophy, impressed by a 3D printer and cute googly eyes
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Reposted by Gonzalo Villanueva Martin
Javi Martínez-López @javiml221098.bsky.social · 21/02/2025
A great example to start this section is Mal-ID (MAchine Learning for Immunological Diagnosis). A cool acronym for the method presented in this paper that uses machine learning to predict disease status from BCR & TCR repertoires. A great name for an impressive work! www.science.org/doi/10.1126/...
science.org
Disease diagnostics using machine learning of B cell and T cell receptor sequences
Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system’s own record of antigen ...
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 11/02/2025
La ciencia progresa, pero no al mismo ritmo para todos #11F
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Reposted by Gonzalo Villanueva Martin
Gabriel Ramírez-Vilchis @gabrielramirezv.bsky.social · 30/01/2025
Single-cell RNA sequencing is very important when studying gene expression. I found scDotPlot package developed by @laufer.bsky.social, and I think it could be a very useful tool to analyze and plot scRNA-seq data using R. You can find more information in bioconductor.org/packages/rel...
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 31/01/2025
New paper 🚨 What can COVID-19 teach us about systemic sclerosis (SSc)? 🤔 In our newly accepted paper in Rheumatology(Oxford) we explored the shared genetic component between COVID-19 and SSc to better understand their immune mechanisms and lung involvement 🧵👇 academic.oup.com/rheumatology...
academic.oup.com
Cross-trait GWAS in COVID-19 and systemic sclerosis reveals novel genes implicated in fibrotic and inflammation pathways
AbstractObjectives. COVID-19 and systemic sclerosis (SSc) share multiple similarities in their clinical manifestations, alterations in immune response, and
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Reposted by Gonzalo Villanueva Martin
Javi Martínez-López @javiml221098.bsky.social · 13/01/2025
It's always good to begin with a friendly reminder 📊
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Reposted by Gonzalo Villanueva Martin
Gonzalo Borrego-Yaniz @goboru.bsky.social · 13/01/2025
And final bonus fact: as a total nerd project, @javiml221098.bsky.social and I made a R package to use color palettes based on movies from Studio Ghibli in your plots 🔥 github.com/goboru/Ghibl...
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