Reactive oxygen species (ROS) are not only toxic byproducts of mitochondrial activity but also important signaling molecules in eukaryotes. To fulfill this signaling role, ROS production must be tight...

Abstract. Fungi occupy a wide range of ecological niches in which they compete or associate with other organisms through the perception of external signals

The review covers recent advances on fungal GPCRs, including their molecular interactions and physiological roles. Illustration created with BioRender.com.

Chimeric antigen receptor T (CAR-T) cell therapy uses engineered donor T cells to recognize and eliminate cancer cells through cognate antigen-dependent activation. Here authors develop an alternative...

Every year, fungal pathogens destroy more than 10% of the world’s major crops, threatening global food security, biodiversity, and farmers’ livelihoods. It’s a silent crisis that costs billions and fu...

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

Defining the minimal genetic requirements for cellular life remains a fundamental question in biology. Genomic exploration continually reveals novel microbial lineages, often exhibiting extreme genome...

Nuclei define eukaryotes, enabling macromolecular compartmentalization and cellular regulation. Each nucleus is believed to contain one or more haploid sets of chromosomes (1N). However, we discovered...

Crop health is improved by abundance of beneficial soil fungal genera and reduced by abundance of soil fungal pathogens, according to analysis of satellite-derived normalized difference vegetation ind...