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Gina Lucas

@genelocus.bsky.social

29 followers 41 following 0 posts

PhD Candidate in the Samuk Lab at UC Riverside. Interested in evolutionary genetics ⊹ ࣪ ˖ 𓆦‪ ♡ 𓆝 ⊹ ࣪ ˖

Posts Replies Media

Reposted by Gina Lucas

Kieran Samuk @ksamuk.bsky.social · 03/08/2026

Just posted: a group paper describing major updates to my software pixy, for population genetic summary statistics. www.biorxiv.org/content/10.6... New since 2021: arbitrary ploidy, multiallelic sites, missingness-aware Watterson's θ and Tajima's D, Hudson's FST, multicore execution!

Alt text: Schematic of the pixy workflow. Left, inputs: a bgzipped, tabix- or CSI-indexed VCF with callable sites supplied as an all-sites VCF or gVCF blocks, a populations file, and optional BED and sites files. Centre, core: windowing by fixed width, BED or region; statistic selection; options for Hudson's FST, multiallelic SNPs, automatic ploidy detection and multicore execution. Right, outputs: one TSV per statistic for pi, dxy, FST, Watterson's theta and Tajima's D, with raw count columns for exact aggregation. Bottom, development: GitHub fork and pull request, local checks with ruff, mypy and pytest, continuous integration across Python 3.10 to 3.14, and distribution through conda-forge. Features new since the 2021 release are badged "new".

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Reposted by Gina Lucas

Molecular Biology and Evolution @molbioevol.bsky.social · 05/05/2025

@akopyan.bsky.social et al. analysed 168 genomes of Atlantic silverside, showing that high gene flow leads to clustered divergence in large inversions, while low recombination at centromeres mimics differentiation. 🔗 doi.org/10.1093/molb... #evobio #molbio #inversions

doi.org

Genetic Differentiation is Constrained to Chromosomal Inversions and Putative Centromeres in Locally Adapted Populations With Higher Gene Flow

Abstract. The impact of genome structure on adaptation is a growing focus in evolutionary biology, revealing an important role for structural variation and

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Reposted by Gina Lucas

bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 21/04/2025

Evidence of parental care as a novel reproductive isolating mechanism www.biorxiv.org/content/10.1101/202…

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