iiinova — where your digital self keeps evolving

Frederik Post @freddyomics.bsky.social · 11/09/2025

My first PhD paper on the spatial characterization of colon organoids is finally out! Thanks to @hausmannannika.bsky.social for spearheading this collaboration with me. Read more about the study in the post by @mannlab.bsky.social.

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Reposted by Frederik Post

Annika Hausmann @hausmannannika.bsky.social · 10/09/2025

Very happy to share that part of my postdoc work @ucph.bsky.social @kimbakjensen.bsky.social lab is out now in @cp-cellsystems.bsky.social! In close collaboration with @freddyomics.bsky.social @mannlab.bsky.social we show that orthotopically transplanted organoids recapitulate in vivo phenotypes 👇🏼

kwnsfk27.r.eu-west-1.awstrack.me

ScienceDirect.com | Science, health and medical journals, full text articles and books.

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Reposted by Frederik Post

Mann Lab @mannlab.bsky.social · 16/04/2025

Our paper is out in Nature today! We use Deep Visual Proteomics (DVP) to dissect α1-antitrypsin deficiency (AATD) in human liver at single-cell resolution. Let us take a tour through proteotoxic stress in intact human tissue — one hepatocyte at a time. www.nature.com/articles/s41...

nature.com

Deep Visual Proteomics maps proteotoxicity in a genetic liver disease - Nature

High-resolution spatial proteomics were used to map molecular events during hepatocyte stress in pseudotime across all fibrosis stages, recapitulating known disease progression markers and revealing e...

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Reposted by Frederik Post

Mann Lab @mannlab.bsky.social · 19/02/2025

Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️

nature.com

Plasma proteome variation and its genetic determinants in children and adolescents - Nature Genetics

This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.

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