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Fitzsimons Lab, University of Amsterdam

@fitzsimonslab.bsky.social
61 followers 141 following 10 posts

As a mechanic dreams about fixing broken things, at the Fitzsimons Lab we dream about repairing the damaged brain.

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Reposted by Fitzsimons Lab, University of Amsterdam
Cell Stem Cell @cp-cellstemcell.bsky.social · 24/04/2026
Online Now! Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer’s pathology and cognitive resilience #stemcells
dlvr.it
Transcriptional profiles of immature neurons in aged human hippocampus track Alzheimer’s pathology and cognitive resilience
Tosoni and colleagues identify immature neurons in the aged human hippocampus with signatures of younger biological age and cellular fitness. Their molecular programs and intercellular interactions are disrupted in Alzheimer’s disease but preserved in cognitive resilience, suggesting that these cells contribute to maintaining hippocampal homeostasis despite Alzheimer’s pathology.
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Fitzsimons Lab, University of Amsterdam @fitzsimonslab.bsky.social · 18/09/2025
www.wired.com/story/can-ps... interesting story, curious to see it developing
wired.com
Why Former NFL All-Pros Are Turning to Psychedelics
Research into whether drugs like ayahuasca can mitigate the effects of traumatic brain injury is in its infancy. Pro athletes like the Buffalo Bills’ Jordan Poyer are forging ahead anyway.
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Fitzsimons Lab, University of Amsterdam @fitzsimonslab.bsky.social · 01/08/2025
www.altmetric.com/case-studies...
altmetric.com
Accelerating impact analysis with Altmetric
Learn how Vrije Universiteit Amsterdam (VU) uses Altmetric accelerate research impact analysis.
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Reposted by Fitzsimons Lab, University of Amsterdam
Giorgia Tosoni @giorgitos.bsky.social · 03/07/2025
Important perspective on a fascinating study from the Frisén group, which used machine learning to identify neural progenitors in the adult human brain, a fresh lens on a long-standing debate 💥 Always exciting to see this field evolve, and grateful to be part of it @labsalta.bsky.social
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Reposted by Fitzsimons Lab, University of Amsterdam
Giorgia Tosoni @giorgitos.bsky.social · 24/06/2025
Hora est 🎓 Last Thursday, I defended my PhD at the University of Amsterdam, @nin-knaw.bsky.social—graduated cum laude ✨ Huge thanks to my amazing supervisor @labsalta.bsky.social, co-promoters Paul Lucassen, Inge Huitinga & @fitzsimonslab.bsky.social. Thanks to all who made the day unforgettable!
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Fitzsimons Lab, University of Amsterdam @fitzsimonslab.bsky.social · 18/06/2025
What is an adult hippocampal neural stem cell? In our new collaboration with Evgenia Salta's lab, we propose an operational definition based on conserved gene signatures across seven previous studies, and we use it to understand how NSCs change as they age onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Cross‐Analysis of Single‐Cell Transcriptomic Datasets Reveals Conserved Neurogenic Gene Signatures and New Insights Into Neural Stem Cell Aging
Here, we reanalyze single-cell RNA sequencing datasets demonstrating hippocampal adult neural stem cell (NSC) heterogeneity to resolve classification inconsistencies and identify conserved gene marke...
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Reposted by Fitzsimons Lab, University of Amsterdam
Aging Science News @agingbiology.bsky.social · 12/06/2025
Cross-Analysis of Single-Cell Transcriptomic Datasets Reveals Conserved Neurogenic Gene Signatures and New Insights Into Neural Stem Cell Aging onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com
Cross‐Analysis of Single‐Cell Transcriptomic Datasets Reveals Conserved Neurogenic Gene Signatures and New Insights Into Neural Stem Cell Aging
Here, we reanalyze single-cell RNA sequencing datasets demonstrating hippocampal adult neural stem cell (NSC) heterogeneity to resolve classification inconsistencies and identify conserved gene marke...
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Fitzsimons Lab, University of Amsterdam @fitzsimonslab.bsky.social · 26/04/2025
CTE is a devastating disease that recieves very little attention from the health community. For these patients, everything starts with a traumatic brain injury
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Reposted by Fitzsimons Lab, University of Amsterdam
Nature @nature.com · 26/04/2025
Several research institutes in Germany are joining a worldwide grassroots effort to save science data sets that researchers fear could be deleted by US President Donald Trump’s administration go.nature.com/4jnEXnt
go.nature.com
Major European institutes join race to save US science data
Nature - As the administration of US President Donald Trump slashes budgets, crucial climate and other data sets could disappear.
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Fitzsimons Lab, University of Amsterdam @fitzsimonslab.bsky.social · 20/03/2025
Join us in Amsterdam!
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Reposted by Fitzsimons Lab, University of Amsterdam
The New York Times @nytimes.com · 20/02/2025
Nearly one in 10 adults in the U.S. identifies as LGBTQ, according to a large analysis from Gallup released Thursday — almost triple the share since Gallup began counting in 2012, and up by two-thirds since 2020. nyti.ms/42ZZGIN
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