During 2000–20, NHS coverage of new drugs displaced more population health than it generated. Our results highlight the inherent trade-offs between individuals who directly benefit from new drugs and ...

A department Clinical Trials Unit coordinated trial has found most penicillin 'allergies' are not real. Safely removing these incorrect labels can lead to better patient treatment and is a vital step ...

NHS England » Decision support tool: making a decision about cataracts

87% of posts mentioned the benefits of the tests, while only 15% mentioned potential harms.

In this episode, we talk to Dr Pete Edwards about effective safety netting practices.

Podcast Episode · Talking Meds - A PrescQIPP podcast · 21/02/2025 · 19m

Sam Finnikin and colleagues argue that guidelines should focus less on population level risk thresholds and more on shared decision making conversations based on individualised risk and patient prefer...

Clinical prediction models estimate an individual’s risk (probability) of a health related outcome to help guide patient counselling and clinical decision making. Most models provide a single point es...

Mathew discusses GP access to magnetic resonance imaging (MRI).1 Multiple studies have been published in which patients without symptoms underwent MRI of the knee and were found to have abnormalities...

Guideline directed medical therapy for heart failure for older people with frailty may do more harm than good, say Henry Woodford and colleagues The management of heart failure is evolving. Recent c...

Despite the availability of effective therapies for patients with chronic kidney disease, type 2 diabetes, and hypertension (the kidney-dysfunction triad), the results of large-scale trials examini...

Dr Kevin Fernando and the Guidelines in Practice Team explore updated recommendations on hypertension from the European Society of Cardiology

Instrumental variables (IV) is a central strategy for identifying causal effects in absence of randomized experiments. Clinicians and epidemiologists may find the intuition of IV easy to grasp by comp...

Amid a sharp rise in mental health conditions, critics say we have started to pathologise “ordinary human unhappiness”.

A leading trust CEO, ICS leader and policy guru join the HSJ podcast to tell us what's needed from the government's 10-year health plan.

I remember a consultation with a patient of mine. They had just had an operation. The surgeon had told them that they would need three months off work and provided them with a fit note for two week…