Cell-state diversity drives tissue adaptability, repair, and disease resilience, but capturing this complexity is a challenge. Current approaches rely on transcriptional profiling and overlook organel...

A team led by HHMI Janelia Research Campus Fellow Daniel Feliciano developed a new, cost-effective technique that uses information about the structures inside cells to reveal the condition of tissues ...

The vertebrate brain develops through a precisely orchestrated sequence of events, where neural progenitors generate neuronal diversity. However, the importance of stem cell origin in the acquisition ...

Cellular heterogeneity within complex tissues and organs is essential to coordinate biological processes across biological scales. The effect of local cues and tissue microenvironments on cell heterog...