Abstract. Population-scale long-read DNA sequencing (PLRS) is rapidly reshaping our understanding of genomic variation in humans and non-model species. In

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Structural variants (SVs) are widespread in vertebrate genomes, yet their evolutionary dynamics remain poorly understood. Using 45 long-read de novo genome assemblies and pangenome tools, we analyze S...

Deep learning methods identified a large and evolutionarily conserved X-linked low recombination region in placental mammals that serves as both a barrier to gene flow in hybridizing lineages and an a...

Groundbreaking pangenomic study suggests big DNA flip may have made small bird resistant to some diseases.