iiinova — where your digital self keeps evolving

Reposted by Esther Rodríguez Correa

Mick Milsom @milsommick.bsky.social · 25/05/2026

How do lineage-biased HSC states relate to each other? check out: rdcu.be/fkASJ in @natcellbio.nature.com Collaboration with @simonhaas.bsky.social @bihatcharite.bsky.social & MDC; Thomas Höfer & Daniel Hübschmann @dkfz.bsky.social @nct-heidelberg.bsky.social

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Reposted by Esther Rodríguez Correa

Simon Haas @simonhaas.bsky.social · 07/08/2025

Excited to share our latest paper @natmethods.nature.com We present a high-throughput framework to map cellular interactions at ultra-high scale – broadly applicable from whole-organism immune response mapping to personalized therapy response prediction (1/4). www.nature.com/articles/s41...

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Reposted by Esther Rodríguez Correa

verat-h.bsky.social @verat-h.bsky.social · 18/02/2025

Thrilled to share that our work from Trumpp Lab @hi-stem @dkfz.bsky.social is out in Nature. We provide the first single-cell data on neurons infiltrating pancreatic tumors, offering new insights into cancer therapy. #cancerneuroscience @cn-hd.bsky.social www.nature.com/articles/s41...

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Reposted by Esther Rodríguez Correa

Simon Haas @simonhaas.bsky.social · 08/02/2025

Ever wondered what drives hematopoietic stem cell (HSC) heterogeneity? In this preprint, our collaborative team uncovered that differences in HSC reconstitution kinetics play a key role in shaping stem cell heterogeneity and lineage biases. doi.org/10.1101/2025... (1/2)

doi.org

A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells

Residing at the top of the hematopoietic hierarchy, long-term hematopoietic stem cells (HSCs) are capable of self-renewal and sustained blood cell regeneration. Over the past decades, single-cell and ...

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