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Epigenome Technologies @epigenometech.bsky.social · 15h

New Epigenome Technologies Blog! epigenometech.com/blog/posts/2... "Droplet Paired-Tag Identifies Potential Therapeutic Targets for Heart Failure" #Epigenetics #Chromatin #HeartFailure #PairedTag #EpigenomeTech

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Epigenome Technologies @epigenometech.bsky.social · 19h

Epigenetics Update - Alzheimer's disease target and drug discovery by leveraging multiomics and electronic health data www.nature.com/articles/s41... Feixiong Cheng (@clevelandclinic.bsky.social) in Nature Neuroscience #Epigenetics #Alzheimers #MultiOmics #Chromatin --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 14/10/2026

Epigenetics Update - Histone lactylation scarring transmits metabolic and epigenetic memory across the gut-liver axis www.cell.com/cell-metabol... #Epigenetics #Chromatin #Lactylation #EpigeneticMemory #Metabolism #GutLiverAxis --- High-resolution insights without cell sorting; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 13/10/2026

Epigenome Technologies offers an end-to-end Single-Cell CUT&Tag service Our expert scientists run the entire workflow on your samples - from preparation to data analysis #Epigenetics #SingleCell #CUTandTag Find out more at: u.epigenome.us/Xz86EjGJ

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Epigenome Technologies @epigenometech.bsky.social · 13/10/2026

Epigenetics Update - Metabolic reprogramming of pathogenic CD4+ T helper cells attenuates inflammatory bowel disease in mice www.science.org/doi/10.1126/... #Epigenetics #Chromatin #Metabolism #IBD #Inflammation --- Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 13/10/2026

Epigenetics Update - Spatially resolved genome architecture in mouse embryonic development www.cell.com/developmenta... Xiang Li (CAS) in @Developmental Cell #Epigenetics #Chromatin #SpaceA --- Empower your research with high-res epigenetic insights at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 12/10/2026

New from Epigenome Technologies: the first fully validated Single-Cell CUT&Tag kit Fully compatible with 10x Chromium® (ATAC), Fluent PiP-seq®, or BD Rhapsody #Epigenetics #SingleCell #CUTandTag Find out more at: u.epigenome.us/NYjSGQao

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Epigenome Technologies @epigenometech.bsky.social · 12/10/2026

Epigenetics Update - Chromatin accessibility trajectories reveal pre-cancerous epigenetic priming and an acid-driven immunotherapy-resistant gastric cancer subtype www.cell.com/cancer-cell/... #Epigenetics #Chromatin #Cancer #EpigeneticPriming #Immunotherapy --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 12/10/2026

Epigenetics Review – Arginine methylation in immunoregulation: Mechanisms and therapeutic targeting www.cell.com/cell-chemica... Song-Iee Han & Akiyoshi Fukamizu (Univ. Tsukuba) in Cell Chem Biol #Epigenetics #Review #ArginineMethylation #Chromatin --- Gain deeper insights; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 09/10/2026

Epigenetics Preprint – Single-Nucleus Multi-Omic Atlas Maps Regulatory Architecture and Non-Coding Variant Effects across Adult Human Tissues www.biorxiv.org/content/10.6... #Epigenetic #Preprint #SingleCell #MultiOmic --- Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 09/10/2026

Epigenetics Update - An epigenetic program dictates MYC amplification dynamics that promote transient, extrachromosomal, and inherited genomic events www.cell.com/molecular-ce... Benjamin Ferman & Johnathan Whetstine in Mol Cell #Epigenetics #MYC #ecDNA #KDM4C #Chromatin --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 08/10/2026

Epigenetics Update - Single-allele nanoscale mapping of regulatory variants www.nature.com/articles/s41... Thomas A. Milne, Jim R. Hughes, and jojdavies.bsky.social (ox.ac.uk) in Nature Genetics #Epigenetics #Chromatin #Regulation --- Gain deeper insights into gene regulation; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 08/10/2026

Epigenetics Update - Single-molecule chromatin tracing reveals a diversity of megabase heterochromatin domains www.nature.com/articles/s41... Dania Camila Pulido-Barrera and Susan E. Mango (unibas.ch) in NSMB #Epigenetics #Chromatin #Heterochromatin --- High-resolution insights; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 07/10/2026

New Epigenome Technologies Blog! u.epigenome.us/RIPipZpR "Promoter Reinforcement Revealed as a New Therapeutic Resistance Mechanism" Analyzing chromatin conformation in treatment-resistant cancer cells identifies promoter reinforcement as a resistance mechanism. #Epigenetics #Chromatin #Cancer

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Epigenome Technologies @epigenometech.bsky.social · 07/10/2026

Epigenetics Update - Type 2 immune history trains lung macrophages for viral disease tolerance www.nature.com/articles/s41... payalyokota.bsky.social and khannakm.bsky.social (NYU Grossman School of Medicine) in nature.com #Epigenetics #Chromatin --- Cancer, immunology, aging; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 07/10/2026

Epigenetics Update - Reactivation of the embryonic ζ-globin gene ameliorates severe forms of α-thalassemia www.nature.com/articles/s41... Christian Babbs, Mira T. Kassouf, Douglas R. Higgs in Nat Genet #Epigenetics #Chromatin #Thalassemia --- Empower your research at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 06/10/2026

Epigenetics Update - Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma www.nature.com/articles/s41... Erik P. Sulman and janeskok.bsky.social in Nat Commun #Epigenetics #Chromatin #Glioblastoma #DNAdamage --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 05/10/2026

New Epigenome Technologies Blog! epigenometech.com/blog/posts/2... "Replication Stress Induces Genome Organization via G9a and CTCF" Links between chromatin changes and higher-order genome organization maintain genome integrity in response to replication stress #Blog #Chromatin #Epigenetics

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Epigenome Technologies @epigenometech.bsky.social · 05/10/2026

Epigenetics Update - A metabolic–epigenetic switch governs multicellular cardiac repair following succinate dehydrogenase inhibition www.nature.com/articles/s44... Ahmed I. Mahmoud (sbpdiscovery.bsky.social) in Nat Cardiovasc Res #Epigenetics #Metabolism #Chromatin --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 05/10/2026

Epigenetics Update - Spatially resolved multiomics of human meningeal development reveal lineage and disease dynamics www.nature.com/articles/s41... Sarah A. Teichmann (cam.ac.uk) in Nature Cell Biology #Epigenetics #Multiomics #Chromatin #Meninges --- Gain deeper insights epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 02/10/2026

Learn about single-cell epigenetic profiling by downloading our guide to single-cell CUT&Tag and single-cell Paired-Tag, which provides comparisons to other methods and bioinformatic insight #Epigenetics #Multiomics #CUTandTag #10XGgenomics #ChIPSeq #SingleCell #PairedTag u.epigenome.us/mHSAqLpl

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Epigenome Technologies @epigenometech.bsky.social · 01/10/2026

Our expansion of single-cell epigenetics assays continues! The Epigenome Technologies scCUT&Tag assay is now compatible with the BD Rhapsody platform #Epigenetics #BDrhapsody #CUTandTag #Chromatin #Multiomics #Singlecell #CUTandRUN #ChIPseq #ATACseq Learn more here: u.epigenome.us/NYjSGQao

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Epigenome Technologies @epigenometech.bsky.social · 01/10/2026

Epigenetics Update - Enhancer Tuning by Sequence-Specific Repressors www.biorxiv.org/content/10.6... lichino.bsky.social and Joanna Wysocka (stanfordmedicine.bsky.social) in BioRxiv #Epigenetics #Enhancers #Chromatin #DAFseq --- Gain deeper insights into gene regulation; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 01/10/2026

Epigenetics Update - Methylation Mesa define functional regulatory elements for targeted gene activation www.nature.com/articles/s41... Daniel G. Tenen & Mahmoud Adel Bassal (Harvard Medical School) in Nat Commun #Epigenetics #MethylationMesa #DNAm --- High-resolution insight; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 30/09/2026

We have recently expanded our single-cell epigenetics assays! Our Emulsion scCUT&Tag assay is now compatible with the Illumina PIP-seq platform #SingleCell #EpigenomeTech #PairedTag #Multiomics #Epigenetics #scCUTandTag #PIPseq Learn more here: u.epigenome.us/NYjSGQao

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Epigenome Technologies @epigenometech.bsky.social · 30/09/2026

Epigenetics Update - A cross-species single-cell kidney epigenome atlas reveals epithelial-dominant aging-like states in disease www.nature.com/articles/s43... Sanjay Jain and Kun Zhang (Altos Labs) in Nature Aging #Epigenetics #Aging #Epigenome #SingleCell #Multiomics --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 30/09/2026

Epigenetics Update - Atlas of cell types and regulatory elements underlying human facial diversity www.nature.com/articles/s41... alekerickson.bsky.social, Yaakov Gershtein, and Rozalina Galimullina in Nat Genet #Epigenetics #FacialDiversity #Chromatin --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 29/09/2026

Download our poster to learn how we applied Droplet Paired-Tag to Alzheimer's disease post-mortem brain tissue to reveal specific cellular changes and potential therapeutic targets #Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics #Alzheimers u.epigenome.us/I8R4vBn2

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Epigenome Technologies @epigenometech.bsky.social · 29/09/2026

Epigenetics Update - Divergent medulloblastoma chromatin states disclose KDM2B as a selective dependency www.nature.com/articles/s41... Stefan M. Pfister and doctorpauln77.bsky.social in Nature Genetics #Epigenetics #Medulloblastoma #Cancer #KDM2B --- Gain deeper insights; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 29/09/2026

Epigenetics Update - Linker histone H1.0 loads onto nucleosomes through multiple pathways that are facilitated by histone chaperones www.cell.com/molecular-ce... Ehsan Akbari and Michael G. Poirier (Ohio State University) in Molecular Cell #Epigenetics #Chromatin #Chaperones --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 28/09/2026

Learn how we used Droplet Paired-Tag to assess RNA expression and histone modifications in brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to Alzheimer's #Epigenetics #SingleCell #PairedTag #Multiomics #Alzheimers u.epigenome.us/I8R4vBn2

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Epigenome Technologies @epigenometech.bsky.social · 28/09/2026

Epigenetics Update - Switching of transcriptional control from interferon regulatory factor 2 to interferon regulatory factor 1 drives innate immune cell activation www.cell.com/cell/fulltex... #Epigenetics #Immunity #Chromatin #Interferon --- Empower your research at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 28/09/2026

Epigenetics Update - HOMEODOMAIN-LIKE shapes chromatin architecture and rewires leaf epidermal patterns www.nature.com/articles/s41... Ansar Ali and Chin-Min Kimmy Ho (Academia Sinica) in Nature Communications #Epigenetics #Chromatin #Plants #Leaf --- Discover the breakthrough: epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 28/09/2026

Epigenetics Update - Development of an investigational epigenetic silencer therapy to transcriptionally inactivate viral DNA in chronic hepatitis B www.nature.com/articles/s41... Jennifer L. Marlowe (nChroma Bio) in natbiomedeng.nature.com #Epigenetics #Hepatitis --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 26/09/2026

Epigenetics Perspective - Promotion of long-term health in early life u.epigenome.us/k1iVzU4W Martin Stocker (uniluzern.bsky.social) in PNAS #Epigenetics #Chromatin #Aging #Perspective --- Gain deeper insights into gene regulation; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 25/09/2026

Epigenetics Update - Transgenerational inheritance of altered H3K27me3 in wild-type Caenorhabditis elegans u.epigenome.us/KFiE6Ejh Florian A Steiner (biology-unige.bsky.social) in embojournal.org #Epigenetics #H3K27me3 #Chromatin --- Gain hi-res at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 25/09/2026

Epigenetics Update - Epigenetic training licenses naïve CD8+ T cell metabolic fitness and function u.epigenome.us/QNga66gq Guohong Li and Mingzhao Zhu (CAS) in Science Advances #Epigenetics #Immunity #Chromatin --- Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 25/09/2026

Epigenetics Update - Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral blood u.epigenome.us/SIvyBrCi #Epigenetics #Multiomics #Exercise #Chromatin #Blood --- Empower your research with high-res epigenetic insights at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 24/09/2026

Epigenetics Update - m6A mRNA methylation regulates pancreatic α-cell plasticity u.epigenome.us/KDgUFM6l dariofdejesus.bsky.social and Rohit N. Kulkarni (harvardmed.bsky.social) in natmetabolism.nature.com #Epigenetics #Chromatin #Diabetes --- Discover the breakthrough at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 24/09/2026

Epigenetics Update - Phosphate backbone epitranscriptomics: Discovery of natural RNA phosphorothioates and their writer machinery u.epigenome.us/BipzWmJX Thomas J. Santangelo, Masato Taoka, and Schraga Schwartz in Cell #Epigenetics #Epitranscriptomics #RNAPhosphorothioate --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 24/09/2026

Epigenetics Update - Deletion of a distal IRF4 element prevents inflammation-induced reprogramming of human regulatory T cell fate u.epigenome.us/2JRq9uPW Patrick Ho and Qizhi Tang (ucsanfrancisco.bsky.social) in natimmunol.nature.com #Epigenetics #Inflammation #Chromatin --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 23/09/2026

Epigenetics Update - HMGA1-HP1β axis regulates premature aging in Hutchinson-Gilford progeria syndrome through chromatin remodeling u.epigenome.us/DkINkLJD Yu Zhang, Yichuan Xiao, & Xianling Cong in Nat Commun #Epigenetics #Chromatin #Progeria #Aging --- Empower your research; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 23/09/2026

Epigenetics Update - 3D chromatin remodeling during domestication defines novel targets for crop improvement u.epigenome.us/WSBXe75B Xianlong Zhang and Maojun Wang (Shihezi University) in Cell #Epigenetics #Chromatin #Crops #Domestication --- Discover the breakthrough at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 23/09/2026

Epigenetics Update - Cohesin reshapes replication fork contacts to aid fork slowing and reversal u.epigenome.us/slt1VlCs daniga90.bsky.social, Ana Losada, and lopeslab.bsky.social in nature.com #Epigenetics #Cohesin #Chromatin #Forks --- Hi-res insights without cell sorting; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 22/09/2026

Epigenetics Update - Rapamycin targetome mining identifies RBBP7 as a druggable epigenetic vulnerability in hepatocellular carcinoma u.epigenome.us/jje91JhP Bing Shan & Yaoyang Zhang (CAS) in Cell Chemical Biology #Epigenetics #RBBP7 #Cancer #Rapamycin --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 21/09/2026

Epigenetics Update - 5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia u.epigenome.us/MBe0Tv0n Mingjiang Xu and Chuan He in Molecular Cell #Epigenetics #Chromatin #caRNAs #Leukemia --- Cancer, immunology, and aging; epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 21/09/2026

Epigenetics Update - Type 1 interferon perturbates clonal competition by reshaping human blood development u.epigenome.us/BzWFNOBt Ronald Hoffman and Anna S. Nam (weillcornell.bsky.social) in Nature Genetics #Epigenetics #Interferon #BloodDevelopment --- epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 21/09/2026

Epigenetics Update - Cryo-EM structure, enzymatic activity and genome targeting of canonical PRC1 u.epigenome.us/xluYsD5s Jacques Bonnet and Jürg Müller (mpibiochem.bsky.social) in NSMB #Epigenetics #PRC1 #Chromatin --- Discover the breakthrough at epigenometech.com

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Epigenome Technologies @epigenometech.bsky.social · 18/09/2026

Download our poster to learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements #Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics u.epigenome.us/I8R4vBn2

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Epigenome Technologies @epigenometech.bsky.social · 18/09/2026

Epigenetics Update - Epigenetic repression of IL-1β by C1QBP restricts Dectin-1-mediated host defense against murine invasive candidiasis u.epigenome.us/mQl9jwo4 Yebo Gu & Xin-Ming Jia (Tongji University) in Nat Commun #Epigenetics #Candidiasis #IL1β #Chromatin --- epigenometech.com

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