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Emmottlab

@emmottlab.bsky.social
2.1K followers 1.9K following 44 posts

Lab news and updates for the Emmott lab, RNA virology & proteomics at the Centre for Proteome Research, University of Liverpool, UK Lab website: emmottlab.org

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Emmottlab @emmottlab.bsky.social · 23/06/2026
While Ed can’t make #Nido2026, the lab is well-represented by Max Erdmann, and @rebee.bsky.social ! They will be sharing some of the labs findings on coronavirus replication! Catch Max’s talk tomorrow (Wed) at 3:25, and Rebee’s poster C-0036
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Emmottlab @emmottlab.bsky.social · 04/06/2026
Funded PhD opportunity! (UK students only due to funder restrictions). Investigating cellular heterogeneity in tendon homeostasis and ageing using single-cell proteomics. Deadline 31st July. Project is a collaboration between the Peffers, Emmott and Thorpe labs on equine tendons. Start Oct 2026.
findaphd.com
PhD Programmes, Research Projects & Studentships in the UK & Europe
FindAPhD is a comprehensive guide to PhD studentships and postgraduate research degrees
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Emmottlab @emmottlab.bsky.social · 01/06/2026
In other lab news, Ed was promoted to Professor of Virology & Proteomics. Huge thanks to the team for all their work and support! And to the various mentors and supporters who have helped along the way. We have lots more exciting science coming in the near future!
Staff page for Ed Emmott, with new Professor of Virology & Proteomics title.
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Emmottlab @emmottlab.bsky.social · 29/03/2026
MSCA Postdoctoral Fellowships call opening soon. If you are a strong candidate and interested in submitting a fellowship with us, we have opportunities in several areas of virology/proteomics. See emmottlab.org Call details/eligibility: marie-sklodowska-curie-actions.ec.europa.eu/funding/msca...
marie-sklodowska-curie-actions.ec.europa.eu
MSCA Postdoctoral Fellowships 2026
MSCA Postdoctoral Fellowships enhance the creative and innovative potential of researchers holding a PhD and who wish to acquire new skills through advanced training, international, interdisciplinary ...
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Emmottlab @emmottlab.bsky.social · 20/03/2026
New preprint! Current T7-based MNV reverse genetics can be performed by co-transfecting plasmids encoding T7 RNA polymerase and vaccinia capping enzymes. We see a further 100-1000-fold boost in titres by incorporating CD300lf-expressing BSR-T7 cells into this system. www.biorxiv.org/content/10.6...
biorxiv.org
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Emmottlab @emmottlab.bsky.social · 23/02/2026
Funded PhD studentship (UK students only) available on clinical proteomics, application deadline 22nd March for Oct 2026 start! This project seeks to understand treatment responses to exacerbations experienced by people with CF using proteomics. www.findaphd.com/phds/project...
findaphd.com
Proteomic Signatures of Treatment Response During Pulmonary Exacerbations in Cystic Fibrosis at University of Liverpool on FindAPhD.com
PhD Project - Proteomic Signatures of Treatment Response During Pulmonary Exacerbations in Cystic Fibrosis at University of Liverpool, listed on FindAPhD.com
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Emmottlab @emmottlab.bsky.social · 06/02/2026
Congrats to Dr @stephenholmes.bsky.social on passing his PhD viva today! Thanks to examiners Al Darby and @mtrost.bsky.social!
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Emmottlab @emmottlab.bsky.social · 11/12/2025
For those who missed the British science festival in September, the recordings and mini documentary for antiviral roller skating are now out!
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Emmottlab @emmottlab.bsky.social · 06/12/2025
Another new preprint! This time looking at flavivirus NS5 interactions with our collaborator Armando Arias - www.biorxiv.org/content/10.6...
biorxiv.org
Mitophagy-related prohibitin 2 is an orthoflavivirus restriction factor targeted for degradation during infection
Mitophagy selectively removes depolarised and damaged mitochondria, promoting cell viability. Some members of the Orthoflavivirus genus activate mitophagy to allow extended replication times in a surv...
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Emmottlab @emmottlab.bsky.social · 03/12/2025
New preprint from the lab, and joint first authors @biomarkella.bsky.social and @stephenholmes.bsky.social! Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis www.biorxiv.org/content/10.6...
biorxiv.org
Single-cell phenotypic analysis and multiplet detection through incorporation of microscopy data into cellenONE-based single-cell proteomic data analysis
The reliability of single-cell proteomics (SCP) is intrinsically linked to the fidelity of cell isolation; however, the identification of co-isolated cells (doublets or multiplets) remains a persisten...
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Emmottlab @emmottlab.bsky.social · 25/11/2025
New preprint: Viral protease-mediated polyprotein processing in human astroviruses Great collaboration with Lulla lab. And the first of @leandroxneves.bsky.social proteolysis stories. More coming soon! www.biorxiv.org/content/10.1...
biorxiv.org
Viral protease-mediated polyprotein processing in human astroviruses
Positive-sense RNA viruses often encode large polyproteins that are proteolytically processed by viral and host proteases into functional replication proteins. Astroviruses infect intestinal and neuro...
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Emmottlab @emmottlab.bsky.social · 18/11/2025
New preprint: IFIT3 controls IFIT1 accumulation and specificity preventing self mRNA targeting during the innate immune response. www.biorxiv.org/content/10.1... Led by Renata Fleith from the Sweeney lab.
biorxiv.org
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Emmottlab @emmottlab.bsky.social · 03/11/2025
Funded PhD opportunity through the DiMeN DTP: studying HEV proteolysis. You’ll be primarily based in the Herod lab at Leeds, and work with us on the use of MS-based proteomics to study proteolysis! www.findaphd.com/phds/project...
findaphd.com
MRC DiMeN Doctoral Training Partnership: Molecular Regulation of Proteolysis by Hepatitis E Virus as a Basis for Therapeutic Intervention at University of Leeds on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Molecular Regulation of Proteolysis by Hepatitis E Virus as a Basis for Therapeutic Intervention at University of Leeds, listed on FindAPhD.com
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Antiviral Roller Skating @antiviral-rskating.bsky.social · 12/09/2025
We are still buzzing from our show! Here’s some snaps of what you missed… in case you were wondering…. Huge thank you to the whole production team and the people who made this happen! @microbiologysociety.org @britsciassoc.bsky.social @emmottlab.bsky.social @livuninews.bsky.social #BSF25
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Emmottlab @emmottlab.bsky.social · 09/09/2025
The lab is being represented at the IX International Calicivirus Conference in Banff by @tartanvirus.bsky.social! Catch Frazer to talk protease substrates and proteomics.
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Emmottlab @emmottlab.bsky.social · 24/08/2025
Led by @idb-virology.bsky.social, the lab is contributing to #BSF25 with a performance of antiviral roller skating! Working with Liverpool roller birds, and supported by the BSF and @microbiologysociety.org
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Antiviral Roller Skating @antiviral-rskating.bsky.social · 24/08/2025
👨‍🔬Scientific Advisors Drs. Max Edrmann & Ed Emmott @edemmott.bsky.social 🎭 Inspiration: "Bus Regulation: The Musical" by Ellie Harrison @ellieharrison.bsky.social 💷 Funded by @microbiologysociety.org & @britishscienceassociation.bsky.social #bsf25 #scicomm #sciencecommunication #skating #sciart
Photo of Dr Max Erdmann overlaid with text reading "Scientific Advisors Dr. Max Erdmann and Dr Ed Emmott" with the Emmott Lab logo beneath the text.Graphic with a greyscale background that reads "inspired by Bus Regulation: The Musical created by Ellie Harrison. Funding sources: Microbiology Society and British Science Association
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Antiviral Roller Skating @antiviral-rskating.bsky.social · 24/08/2025
🤝 A collaboration between @liverpooluni.bsky.social & Liverpool Roller Birds ✍️🎬 Written, Directed & Produced by Dr. I'ah Donovan-Banfield @idb-virology.bsky.social 👯‍♀️Choreographed by Ani Bosco 📸 Director of Photography Dr. Rebee Penrice-Randal @rebee.bsky.social 📹 Videography by Paroketh Films
A photo of I'ah Donovan-Banfield presenting introductory slides to the cast, with text above reading: "written, Directed and Produced by I'ah Donovan-Banfield" A photo of Ani Bosco, with her back to the camera, leading the choreography of the first rehearsal with five skaters in the background with joined hands. Text overlaid reads "Choreographed by Ani Bosco"Photos of [left to right] Director of Photography Dr Rebee Penrice-Randal and Videographer Jon Stonehouse of Paroketh Films.
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Emmottlab @emmottlab.bsky.social · 23/08/2025
New paper: collaboration with Cambridge on EMCV 2B* now published journals.asm.org/doi/10.1128/...
journals.asm.org
Encephalomyocarditis virus protein 2B* interacts with 14-3-3 proteins through a phosphorylated C-terminal binding motif | mBio
Encephalomyocarditis virus (EMCV) infects a range of species, causing economically important reproductive disorders in pigs and encephalitis and myocarditis in rodents. Due to its wide host range, it ...
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British Society for Proteome Research @ukbspr.bsky.social · 09/07/2025
Congratulations to Markella Loi from the @emmottlab.bsky.social on winning the Early Career Award for #BSPR2025 and congratulations to @hannahmayging.bsky.social on being the runner
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Emmottlab @emmottlab.bsky.social · 27/06/2025
The lab got a nice bit of news yesterday! LEAF gold!
Certificate for a LEAF gold award for the centre for proteome research
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Emmottlab @emmottlab.bsky.social · 25/05/2025
We have projects available on single-cell proteomics, including methods development, and applications to antiviral development and resistance. If you have a strong background in proteomics and are considering an MSCA, get in touch! marie-sklodowska-curie-actions.ec.europa.eu/news/msca-op...
marie-sklodowska-curie-actions.ec.europa.eu
MSCA opens €404.3 million call for Postdoctoral Fellowships
Postdoctoral Fellowships offer researchers holding a PhD the opportunity to acquire new skills through advanced training and international, interdisciplinary, and inter-sectoral mobility.
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British Society for Proteome Research @ukbspr.bsky.social · 29/04/2025
Nikolai and his group are based at Northeastern University and have been pioneers in the field of single cell proteomics. He will talk about the methods his lab has worked on for multiplexed approaches in SCP, including plexDIA
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British Society for Proteome Research @ukbspr.bsky.social · 29/04/2025
As we get ready for the British Society for Proteome Research annual meeting in Liverpool (July 7-9th), we will start highlighting our amazing speakers. First is @slavov-n.bsky.social who will talk to us about Biological and technological frontiers for single-cell proteomics.
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Rebee @rebee.bsky.social · 03/04/2025
First poster as @emmottlab.bsky.social PDRAs 🥳 #Microsoc25
Rebee and Max selfie in front of microsoc posterMax looking happy with his microsoc poster presentation
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Emmottlab @emmottlab.bsky.social · 23/01/2025
First 2025 paper: delighted to have contributed to this paper on the emergence of a new subgenomic mRNA in SARS-CoV-2 from the Bauer lab journals.plos.org/plosbiology/...
journals.plos.org
Emergence of SARS-CoV-2 subgenomic RNAs that enhance viral fitness and immune evasion
Coronaviruses can evolve novel transcription regulatory sequences, generating new RNA transcripts during human infection. This study identifies a prevalent subgenomic RNA in SARS-CoV-2, which produces...
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Emmottlab @emmottlab.bsky.social · 07/01/2025
Another PhD studentship is available for Oct 2025 start! In a collaboration between the @pirbrightinst.bsky.social and us, you will be investigating the role of novel avian coronavirus accessory genes. See here for more details! www.findaphd.com/phds/project... Deadline 17 Feb, funded for UK only.
findaphd.com
Investigation of Novel Accessory Proteins in the Replication of Infectious Bronchitis Virus at The Pirbright Institute on FindAPhD.com
PhD Project - Investigation of Novel Accessory Proteins in the Replication of Infectious Bronchitis Virus at The Pirbright Institute, listed on FindAPhD.com
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Emmottlab @emmottlab.bsky.social · 17/12/2024
The deadlines for our MRC-funded studentships have now passed, but a funded studentship through the BBSRC NWD DLA is now available for Oct 2025 start in single cell mass spectrometry. See findaphd for more details or drop Ed an email. www.findaphd.com/phds/project...
findaphd.com
BBSRC NWD CASE: Expanding single-cell proteomics into single-cell multi-Omics at University of Liverpool on FindAPhD.com
PhD Project - BBSRC NWD CASE: Expanding single-cell proteomics into single-cell multi-Omics at University of Liverpool, listed on FindAPhD.com
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Emmottlab @emmottlab.bsky.social · 22/11/2024
Reminder - if you are a new PI in UK virology and you aren’t yet registered for RIVR2025 on Jan9-10th in Liverpool, registration closes on December 5th! If you are a new group leader in virology in the UK and aren’t yet on the RIVR mailing list, get in touch to be added.
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Rebee @rebee.bsky.social · 14/11/2024
Loading a mass spec and a nanopore in the same day! Thrilled to be learning another omics method in the @emmottlab.bsky.social 🧬
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Emmottlab @emmottlab.bsky.social · 04/11/2024
We have two funded PhD studentships available through DiMeN_DTP programme for Oct2025 Standard_2025_127: Understanding the mechanisms of norovirus replication (Dr Edward Emmot) Standard_2025_71: Widening the ‘NET’ to identify new treatments for bronchiectasis (Dr Helen Wright)
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Emmottlab @emmottlab.bsky.social · 21/04/2024
Just to warn we do not have any positions available in our lab- some fraudulent adverts are being circulated on LinkedIn and possibly elsewhere - the link to the lab website is real but all the links below and the details are all fake.
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Emmottlab @emmottlab.bsky.social · 05/02/2024
New paper: Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1. Work led by Ileana Georgana from the Goodfellow lab www.mdpi.com/1999-4915/16...
mdpi.com
Porcine Sapovirus Protease Controls the Innate Immune Response and Targets TBK1
Human sapoviruses (HuSaVs) and noroviruses are considered the leading cause of acute gastroenteritis worldwide. While extensive research has focused on noroviruses, our understanding of sapoviruses (S...
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Emmottlab @emmottlab.bsky.social · 19/12/2023
These positions are now available to apply for! - see thread below!
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Emmottlab @emmottlab.bsky.social · 11/12/2023
The lab is hiring PhD students and PDRAs for 2024 start! Projects going in proteomics/mass spectrometry and virology.
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Emmottlab @emmottlab.bsky.social · 06/12/2023
A second funded PhD studentship is available for Oct 2024 start! - Investigating the interactions of Rift Valley fever virus RdRP. You will be primarily based with Alain Kohl at LSTM, working with us on the LC-MS/MS portions. Deadline Jan 24. www.lstmed.ac.uk/study/resear...
lstmed.ac.uk
The host interactome of the Rift Valley fever virus RNA-dependent RNA
AbstractRift Valley fever virus (Bunyavirales, Peribunyaviridae) or short RVFV is emerging arbovirus that can cause disease and death in humans and animals. There are no drugs to treat infection, and
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Emmottlab @emmottlab.bsky.social · 01/12/2023
News is now out officially! Hugely grateful for this award which will let us study coronavirus replication, in particular the role of polyprotein precursors over the next 8 years! Adverts for two new PDRA positions are working through HR and will be up shortly. news.liverpool.ac.uk/2023/12/01/2...
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Emmottlab @emmottlab.bsky.social · 16/11/2023
Funded PhD student ship in the lab for Oct 2024 start - expanding single-cell proteomics to single-cell multi omics. This is a CASE project in collaboration with Cellenion and SwanseaUni. Deadline Jan 15. For details see: www.findaphd.com/phds/project...
findaphd.com
BBSRC NLD Doctoral Training Partnership: Expanding single-cell proteomics into single-cell multi-omi...
PhD Project - BBSRC NLD Doctoral Training Partnership: Expanding single-cell proteomics into single-cell multi-omics at University of Liverpool, listed on FindAPhD.com
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Emmottlab @emmottlab.bsky.social · 04/10/2023
Congrats to Dr Rosie Maher whose preprint on proteomic analysis of pulmonary aspiration from her PhD studies with Rob Benton and Paul McNamara is now available on @medrxivpreprint.bsky.social : www.medrxiv.org/content/10.1...
medrxiv.org
Investigating markers of pulmonary aspiration in bronchoalveolar lavage from children with severe ne...
medRxiv - The Preprint Server for Health Sciences
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Emmottlab @emmottlab.bsky.social · 01/10/2023
New paper: The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity www.cell.com/iscience/ful... Delighted to have contributed to this work, led by Hazel Stewart from the Firth Lab, and Yongxu Lu!
cell.com
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity
The SARS-CoV-2 genome encodes a multitude of accessory proteins. Using comparative genomic approaches, an additional accessory protein, ORF3c, has been predicted to be encoded within the ORF3a sgmRNA....
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Emmottlab @emmottlab.bsky.social · 21/09/2023
Intro! Lab news and updates for the @edemmott.bsky.social lab at the Centre for Proteome Research, University of Liverpool.
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