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U2 covers at the welcome! We’re certainly in Dublin! #ISCT2026 @isctglobal.bsky.social

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Cost effectiveness improved with: Marsella Qesari - deep understanding of the biology of the product in the first instance, paired with rational release assays that don’t need all complex assays repeated for each batch. Patrick Hanley - kits, cartridges for release assays. #ISCT2026 8/8

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Where is the sweet spot for regulation of cell therapies - how does the good in GMP need to be? Patrick Hanley - real world evidence of safe manufacture of cell therapies should assist in defining this and increasing confidence within regulatory bodies to avoid overly burdensome requirements. 7/n

Cath Bollard - In rare diseases (eg paediatrics), non-profit models in academic centers that are already doing IND stage manufacturing would need small/moderate scale investment to scale up to BLA stage from current level of activity. @childrensnational.bsky.social 5/n #ISCT2026

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Becky Cap - Closed systems in decentralised environment not yet fully accepted by regulators. There are important differences between complex processes and stem cell processing or blood banking, but many of the processes are similar. 4/n #vitalant #ISCT2026

Industry, academia, healthcare and regulators need to work together to ensure the goal of effective therapies available to those that need isn’t lost in the process. #ISCT2026 3/n

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What is the right balance of cost (eg arising from regulation) and risk to ensure successful translation of science to good patient outcomes? 2/n #ISCT2026

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Building sustainable business models for CGT - standing room only for these challenging questions. @isctglobal.bsky.social #ISCT2026 1/n

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ISCT @isctglobal.bsky.social · 25/10/2025

Insights into optimization of HSC collection for gene therapy in the first roundtable session for the meeting. #ISCT2026

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Reposted by Emily Blyth

5 more days until the deadline for the Insta-Your-Cells Photo Challenge! Do you have a cell image you want to share? Enter your photo today to win complimentary registration to ISCT 2026 Dublin Scientific Annual Meeting! buff.ly/seIwkM0 Photo submitted by Ling Liu.

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4. HSCT with cytokine induced killer cells from Melissa Berrien-Elliott

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3. The holy grail of transplant - no GVHD and no relapse Melody King on combo Orca-T and CD19/22 CART @stanfordpress.bsky.social

2. Marie Bleakey on CD45RA depletion and minor histocompatibility targeting @fredhutch.bsky.social …