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Eliza James

@elizajames.bsky.social
672 followers 2.3K following 272 posts

n95’s + HEPA’s | Long COVID | MECFS Our leadership & medical providers have failed us on c19 ANTI-profit-over-people

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Eliza James @elizajames.bsky.social · 09/09/2026
The hori hori is the tool you are looking for. You’re welcome.
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Jon Douglas @atranscendedman.bsky.social · 08/09/2026
Researchers studied 200 people with Long COVID and found Viusid, an antioxidant and immune-modulating supplement, improved brain fog, fatigue, sleep, mood and breathing symptoms versus placebo after 210 days. Larger trials are needed. www.eurekaselect.com/article/158201
eurekaselect.com
Effects of Viusid in Long COVID: A Randomized Double-Blind Placebo-Controlled Trial
Introduction: Long COVID syndrome (LCS) is characterized by persistent neurological, respiratory, and systemic symptoms following SARS-CoV-2 infection, with limited effective treatments available. Viu...
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Jon Douglas @atranscendedman.bsky.social · 09/09/2026
Medical University of Gdansk, 83 participants. Long COVID showed impaired microvascular function alongside lower NAD+/NADH balance and NADP, with NAD+ precursors depleted and harmful degradation products increased. onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
Microvascular Dysfunction and Redox Imbalance in Long <fc>COVID</fc>
Objective Endothelial and microvascular dysfunction are key features of Long COVID. Disturbances in cellular redox balance, reflected by altered nicotinamide adenine dinucleotide (NAD+/NADH) dynamic...
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Jon Douglas @atranscendedman.bsky.social · 02/09/2026
Long COVID forced medicine to take post-viral illness seriously. Now the science is closing in on viral persistence, autoimmunity, and immune dysfunction. The treatments need to catch up. www.nature.com/articles/d41...
nature.com
When do infections lead to long COVID? Scientists close in on triggers and treatments for post-viral syndromes
Hundreds of millions of people have long-term conditions as a result of an infection. Researchers are working out how to help them.
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Eliza James @elizajames.bsky.social · 15/08/2026
Oh, right, so…about that…I’ve seen people recently discussing, aghast, that there are ads and promos in digital books these days. Like, placed in the actual story. 🫠 Perhaps old hard copy books while we still have them.
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Jon Douglas @atranscendedman.bsky.social · 13/08/2026
Université de Montréal researchers, 64 participants, found Hp2-2 Long COVID was linked to cognitive decline after exertional stress, with lower brain oxygen extraction and citric acid, suggesting impaired stress adaptation. www.mdpi.com/1422-0067/27...
mdpi.com
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Jon Douglas @atranscendedman.bsky.social · 09/08/2026
University Medical Center Groningen followed 809 people with Long COVID. Recovery slowed markedly after about 235 days. Each additional symptom was linked to a 31% lower rate of recovery. www.thelancet.com/journals/lan...
thelancet.com
Recovery trajectories and predictors of symptom resolution in post-COVID-19 condition: a population-based cohort study
Most individuals with PCC recover, but older adults and those with multiple symptoms are at higher risk of prolonged illness, underscoring the need for ongoing support.
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Jon Douglas @atranscendedman.bsky.social · 08/08/2026
INER researchers followed 32 people after severe or critical COVID. At 3.5 years, VEGF-D rose sharply and coagulation remained abnormal, evidence of persistent vascular and thromboinflammatory dysfunction in Long COVID. link.springer.com/article/10.1...
link.springer.com
Long-term angiogenic and thromboinflammatory signatures in post-COVID-19 syndrome - Angiogenesis
Background Post-COVID-19 syndrome is a major long-term sequela of severe SARS-CoV-2 infection, potentially involving persistent angiogenic and thromboinflammatory dysfunction, though long-term biomark...
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Jon Douglas @atranscendedman.bsky.social · 07/08/2026
University of Texas at Austin researchers studied 1,154 people hospitalized with COVID-19. Nearly half had dormant viruses reactivate. Anellovirus reactivation tracked with immune cell activity and later fatigue, suggesting possible immune dysregulation. www.science.org/content/arti...
science.org
COVID-19 can wake up dormant viruses in the body, large study confirms
Virus reactivations by SARS-CoV-2 could worsen initial symptoms and increase risk of Long Covid
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Jon Douglas @atranscendedman.bsky.social · 07/08/2026
Technical University of Munich, 128 participants. Long COVID was linked to thinning of retinal nerve layers and lower macular volume. Higher MCP-1, a marker of chronic inflammation, tracked with thinner inner retinal layers. www.sciencedirect.com/science/arti...
sciencedirect.com
Subclinical neurovascular and immune correlates of post-COVID-19 syndrome detected by retinal imaging
Post-COVID-19 Syndrome (PCS) encompasses a range of persistent symptoms, including cognitive and autonomic disturbances, potentially linked to microva…
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Jon Douglas @atranscendedman.bsky.social · 05/08/2026
Aarhus University Hospital, 50 people with Long COVID. After 1.4 years, myopathic EMG changes fell from 78% to 18%, yet 56% still had abnormal single-fiber EMG and fatigue persisted, suggesting ongoing neuromuscular dysfunction. www.sciencedirect.com/science/arti...
sciencedirect.com
Persistent neuromuscular dysfunction in long COVID: A quantitative and single fiber EMG follow-up study
Persistent symptoms after SARS CoV-2 infection, often designated as "long COVID”, continue to be an ongoing health issue. Previously, we reported elec…
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Eliza James @elizajames.bsky.social · 05/08/2026
I wonder why have some gave never gotten this but other people are?
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Jon Douglas @atranscendedman.bsky.social · 05/08/2026
Politecnico di Milano review finds COVID-19 may reshape bone itself. Human synchrotron imaging showed larger, rounder osteocyte spaces, while animal models found lasting trabecular loss, pointing to disrupted bone sensing and repair. www.frontiersin.org/journals/bio...
frontiersin.org
Frontiers | Multiscale bone remodeling in COVID-19: from osteoimmune signaling to structural and mechanical impairment
The skeletal consequences of COVID-19 have emerged as an important but still underrecognized component of post-viral systemic disease. Increasing clinical, e...
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Jon Douglas @atranscendedman.bsky.social · 31/07/2026
University of Iowa, 4 to 5 mice per time point showed brain microglia stayed inflamed for 100 days after SARS-CoV-2, despite no productive brain infection. Mitochondrial genes fell, suggesting stressed immune cells may sustain neuroPASC. www.nature.com/articles/s41...
nature.com
Longitudinal analysis reveals myeloid cell contributions to murine neuroPASC pathogenesis - Nature Communications
While prolonged neuroinflammation is considered a hallmark of Post Acute Sequelae of COVID-19 (PASC), its basis is poorly understood. The authors here manifest infiltration of peripheral myeloid cells...
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Jon Douglas @atranscendedman.bsky.social · 31/07/2026
Mie University researchers studied 24 people. ME/CFS blood vesicles were larger and carried a distinct microRNA pattern linked to nerve signaling and cell structure. The finding is promising but needs larger validation. link.springer.com/article/10.1...
link.springer.com
Circulating extracellular vesicles-microRNAs as potential biomarkers for the identification of ME/CFS: differentiating fatigue-related conditions - Journal of Translational Medicine
Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, multi-systemic condition that has gained renewed global attention due to its clinical overlap with the growing...
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Jon Douglas @atranscendedman.bsky.social · 30/07/2026
Goethe University Frankfurt, 279 participants with Long COVID and MRI-defined heart inflammation. Losartan plus low-dose prednisolone did not significantly improve the primary heart function outcome after 16 weeks. www.nature.com/articles/s41...
nature.com
Losartan and prednisolone for post-COVID syndrome and cardiac inflammation: a randomized, double-blind, placebo-controlled trial - Nature Communications
Persistent cardiac symptoms are common in post-COVID syndrome. In the Myoflame-19 trial, losartan plus prednisolone yielded neutral results for the primary outcome, change in left ventricular ejection...
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Jon Douglas @atranscendedman.bsky.social · 30/07/2026
Gladstone Institutes and UCSF, 32 participants. Long COVID showed persistent granzyme B rich CD8+ T cells targeting SARS-CoV-2, CMV and EBV, suggesting the antiviral killing response failed to switch off. www.cell.com/cell-reports...
cell.com
Persistent cytolytic CD8+ T cells recognize SARS-CoV-2 and herpesvirus epitopes in long COVID
Ma et al. perform deep-phenotyping of CD8+ T cells specific for viruses implicated in LC pathogenesis: SARS-CoV-2, CMV, and EBV. These T cells from LC individuals share features of terminal differenti...
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Jon Douglas @atranscendedman.bsky.social · 29/07/2026
Mass General Brigham studied 84 young people. Those with Long COVID had more fibrin microclots and vessel injury. In lab tests, Spike immune complexes made neutrophils release DNA traps that damaged vessel lining cells. www.nature.com/articles/s41...
nature.com
Endothelial activation and thromboinflammation in Long COVID: revisiting the vascular axis in pediatric populations - Pediatric Research
Pediatric Research - Endothelial activation and thromboinflammation in Long COVID: revisiting the vascular axis in pediatric populations
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Jon Douglas @atranscendedman.bsky.social · 27/07/2026
University of Miami, 114 participants. Blood from people with Long COVID showed necroptosis and stress in endothelial and immune cells. Higher endothelial pMLKL tracked with poorer vessel function and worse symptoms. jacionline.org/article/S009...
jacionline.org
Necroptosis and Cellular Stress Characterize Immune and Endothelial Dysfunction in Long COVID
Long COVID, or Post-Acute Sequelae of SARS-CoV-2 infection (PASC), affects a significant proportion of COVID-19 survivors and is associated with persistent fatigue, dysautonomia, and cardiovascular co...
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ME/CFS San Diego @mecfssd.bsky.social · 28/07/2026
Incorrect link on NCNED ME/CFS/LC MRI study: Advanced MRI found distinct brain tissue microstructure changes in ME/CFS and long COVID compared w/ healthy controls which suggest altered white matter may contribute to symptoms inc. fatigue & brain fog. Correct link: www.frontiersin.org/journals/med...
frontiersin.org
Frontiers | Microstructural alterations in brain tissue of ME/CFS and long COVID using diffusion tensor imaging and diffusion kurtosis imaging
IntroductionMyalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and long COVID have overlapping symptoms, such as profound fatigue, cognitive impairm...
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Eliza James @elizajames.bsky.social · 25/07/2026
Our love & grieving for our animals is no different than our love/grief for anyone else. The nervous system responds the same. And, I’d argue, that the love can be so uncomplicated and pure, that the grief can hit even harder for some of us.
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Jon Douglas @atranscendedman.bsky.social · 15/07/2026
King’s College London, 38 people. Serum from those with worse post-COVID fatigue triggered stronger IL-13 and reactive astrocyte signals in human hippocampal cells. Lower serotonin breakdown product 5-HIAA explained 71% of the IL-13 link. www.nature.com/articles/s41...
nature.com
Fatigue after COVID-19 infection is associated with peripheral immunometabolic alterations affecting neuroimmune responses in the hippocampus - Translational Psychiatry
Translational Psychiatry - Fatigue after COVID-19 infection is associated with peripheral immunometabolic alterations affecting neuroimmune responses in the hippocampus
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Eliza James @elizajames.bsky.social · 08/07/2026
Wow!
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Eliza James @elizajames.bsky.social · 08/07/2026
Wow. This image really stopped me in my tracks.
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Eliza James @elizajames.bsky.social · 13/04/2026
I love people sharing their joys like this. My heart lifted with yours. YAY for beautiful, yummy cakes and other delicious delights - and for who take the time to make them gorgeous for us! Thanks for sharing your happiness. May your joy continue. It’s good medicine for our world. 💜🧁🍰
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Eliza James @elizajames.bsky.social · 13/04/2026
I really appreciate your photography. Thanks for connecting and bringing a bit of beauty into my day (& to the world). I find this particular photo really stopped me in my tracks. Gorgeous work. So many of them are.
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Jon Douglas @atranscendedman.bsky.social · 25/01/2026
Harvard researchers studied 143 Long COVID and 170 ME/CFS patients and found both groups showed nearly identical signs of brain blood flow issues, small nerve damage, and widespread autonomic failure. journals.plos.org/plosone/arti...
journals.plos.org
Shared autonomic phenotype of long COVID and myalgic encephalomyelitis/chronic fatigue syndrome
Introduction Long COVID and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are relatively common and disabling multisystem disorders that share overlapping features, including post-infect...
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Jon Douglas @atranscendedman.bsky.social · 24/01/2026
Researchers in South Korea found that SARS-CoV-2 selectively disrupts the brain’s orexin system, leading to lasting cortical neuron damage. Boosting orexin levels reversed this effect, revealing a possible root of Long COVID fatigue and brain fog. www.biorxiv.org/content/10.6...
biorxiv.org
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Christophe Veltsos @drinfosec.bsky.social · 21/01/2026
🎯🎯🎯👇
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Jon Douglas @atranscendedman.bsky.social · 21/01/2026
At Hospital Clínico San Carlos, 157 patients with post-COVID condition showed impaired episodic memory across multiple tests. Difficulties were found in learning, storing, and retrieving information, even with cues and recognition. link.springer.com/article/10.1...
link.springer.com
Episodic memory deficits and processes in post-COVID condition - European Archives of Psychiatry and Clinical Neuroscience
Cognitive dysfunction is one of the most prevalent symptoms in patients with post-COVID condition (PCC) and episodic memory has been highlighted as one of the most impaired cognitive domains in these ...
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Eliza James @elizajames.bsky.social · 20/01/2026
…and more mentions of people arming themselves & saying things is not heard before now. I wondered today if they know this and give a shit.
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Christophe Veltsos @drinfosec.bsky.social · 19/01/2026
🎯🧵by @1goodtern.bsky.social on XTwitter: "A couple of very important studies out just in the last 24 hours confirming what we've been saying for years and years now: Covid infections affect your immune system *badly*. Here's a few..." Full 86-tweet 🧵 (86!!!) threadreaderapp.com/thread/20126...
"A couple of very important studies out just in the last 24 hours confirming what we've been saying for years and years now: Covid infections affect your immune system *badly*.
Here's a few things you may have missed in them."
followed by a partial screenshot of the page for this article:

Persistent attenuation of lymphocyte subsets after mass SARS-CoV-2 infection (Dec 5, 2025)
https://www.sciencedirect.com/science/article/pii/S1201971225005090
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Eliza James @elizajames.bsky.social · 11/01/2026
I saw this earlier on twatter & I think grok said it was ai. Someone seemed to be pushing the message from multiple ai fronts, as far as I saw on my feed.
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Eliza James @elizajames.bsky.social · 08/01/2026
I briefly saw a post w a link about changing Google settings due to the recent changes. I can't locate that now. Can someone assist?
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Christophe Veltsos @drinfosec.bsky.social · 02/01/2026
🚨🧵by @michaelryan756 on XTwitter on Covid, dopamine, & the impact on our brains... "🔹The locus coeruleus is a tiny brainstem structure that acts like the brain’s on/off switch for alertness, threat response, and sleep stages. 🔹During REM sleep..." Full 🧵 threadreaderapp.com/thread/20070...
👉 COVID and the Brain’s Dopamine Buffer: What the Science Actually Shows

Let me unpack what David is talking about here:

🔹 The locus coeruleus is a tiny brainstem structure that acts like the brain’s on/off switch for alertness, threat response, and sleep stages.
🔹 During REM sleep, it’s meant to switch off, so the brain can dream while the body stays still.

This system relies heavily on dopamine to keep sleep, movement, and arousal properly separated.
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Eliza James @elizajames.bsky.social · 01/01/2026
Gorgeous. Where was this?
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Tania J. Spencer @taniaspencer.bsky.social · 01/01/2026
"A reasonable accommodation is any change in the workplace or in the way things are usually done that provides equal opportunities for those with disabilities" - #CleanTheAir #Unions #WakeUp #PreventLongCOVID #ThePandemicIsNotOver Via @kim2112.bsky.social accesspress.org/long-covid-y...
accesspress.org
Long COVID: Your rights at work | Access Press
People who live with Long COVID and are trying to remain part of the workforce need to know their rights. […]
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Christophe Veltsos @drinfosec.bsky.social · 29/12/2025
From ☝️ "As a historian I know what the government does to people it does not want to care for. And as a disabled community member, I see how poverty accelerates community members towards preventable deaths."
As a historian I know what the government does to people it does not want to care for. And as a disabled community member, I see how poverty accelerates community members towards preventable deaths.
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Eliza James @elizajames.bsky.social · 30/12/2025
Welcome to the USA.
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Julia Métraux @juliametraux.bsky.social · 29/12/2025
Wrote about how disappointing it is that Jon Stewart punched down on people masking at @motherjones.com, when people should mind their own business and leave mask wearers be. www.motherjones.com/politics/202...
motherjones.com
Hey Jon Stewart, jokes about wearing masks aren't funny
Critics of the Daily Show host say he's a hypocrite.
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Eliza James @elizajames.bsky.social · 29/12/2025
Done w The Bulwark & Jon Stewart. For folks who like to think they know things, your pompous arrogance & incredible ignorance is showing. Go pick up a scientific journal & keep up, you A-holes. No better than an anti-vaxer/MAGA here. @timmiller.bsky.social @weeklyshowpodcast.bsky.social
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Eliza James @elizajames.bsky.social · 29/12/2025
An extremely mild case of c19 disabled me. I have lost much. Ppl r so mean just bc I’m trying to protect the little I still have when I can actually get myself out to get to an MD appt r devastating. U just amplified that. Done w all of u. @weeklyshowpodcast.bsky.social @timmiller.bsky.social
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Eliza James @elizajames.bsky.social · 29/12/2025
Good lord. :( COVID really harmed me. I’ve lost so much…just from one very mild no-big-deal acute infection.
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Eliza James @elizajames.bsky.social · 29/12/2025
Was this recent?
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Jon Douglas @atranscendedman.bsky.social · 27/12/2025
Shaanxi’s Nuclear Industry 215 Hospital studied 2,000 COVID-19 patients and found at least 15% had bacterial coinfections. In severe cases, nearly all infections were caused by drug-resistant K. pneumoniae or A. baumannii. reference-global.com/article/10.3...
reference-global.com
Analysis of Bacterial Coinfections in Patients with Mild,...
This study aimed to analyze the clinical features and infection status of COVID-19 patients with bacterial infections in Shaanxi Province. A...
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Jon Douglas @atranscendedman.bsky.social · 27/12/2025
Xiamen University scientists analyzed brain tissue from COVID-19 patients and found that infection changes how brain cells process mRNA, disrupting genes tied to memory, cognition, and psychiatric disease. journals.plos.org/plosone/arti...
journals.plos.org
Single-cell alternative polyadenylation analysis reveals mechanistic insights of COVID-19-associated neurological and psychiatric effects
COVID-19 is associated with increased risks of neurological and psychiatric sequelae. Alternative polyadenylation (APA) is ubiquitous in human genes, resulting in mRNA diversity, and has been validate...
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Jon Douglas @atranscendedman.bsky.social · 24/12/2025
McGill researchers followed 545 people with post-COVID syndrome for 15 months and found that severe fatigue stayed high in nearly half. Only a small group improved. Milder fatigue tended to resolve, hinting at different underlying causes. www.medrxiv.org/content/10.6...
medrxiv.org
Change in Fatigue over 15 months in people the Post-Covid Syndrome
Objective The objective was to estimate unique patterns of change in fatigue in people with the Post-Covid Syndrome (PCS) over 15 months. Design/Subjects The Quebec Action for Post-COVID (QAPC) study...
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Jon Douglas @atranscendedman.bsky.social · 24/12/2025
Newcastle University studied 145 people with post-COVID fatigue and found those still fatigued after 200 days had worse symptoms, slower reactions, and signs of brain and muscle dysfunction. Without recovery, neurophysiologic damage appears to build. www.medrxiv.org/content/10.6...
medrxiv.org
Evidence of Accumulating Neurophysiologic Dysfunction in Persistent Post-COVID Fatigue
A major consequence of the COVID-19 pandemic has been the emergence of post-COVID syndrome (PCS), and more specifically, post-COVID fatigue (pCF), with an estimated prevalence of ∼2%. We previously sh...
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Billy Hanlon @bhanlon15.bsky.social · 24/12/2025
Medscape: 'Catch Up On 2025’s Top 5 Stories From Canada' 5. Canadian Cardiologists Must Step Up Care for Long COVID 'This story reminds readers that long COVID is still very much a condition that needs and deserves to be treated...' www.medscape.com/viewarticle/...
medscape.com
Catch Up On 2025’s Top 5 Stories From Canada
Medscape News Canada leverages the most-read Canadian stories in 2025 and makes a list of the five that generate the most interest and, in some cases, controversy.
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Tom Kindlon @tomkindlon.bsky.social · 23/12/2025
Great to see this sympathetic overview article in the LA Times www.latimes.com/doctors-scie... It's long so many if not most patients probably won't agree with every sentence but overall gets across a lot sympathetically. Note: it doesn't focus on any particular news #MEcfs #CFS #PwME
Image of a man with his hand to his face

Chronic fatigue syndrome

Kevin Famuyiro
By Kevin Famuyiro
Senior Content Strategist
Contact
Dec. 20, 2025 5:21 AM PT


16 min
Click here to listen to this article

Key Facts
ME/CFS is characterized by Post-Exertional Malaise (PEM), where symptoms worsen after minimal activity.
The condition is classified as a neurological disease often triggered by viral infections or immune dysfunction.
Diagnosis is a process of exclusion, requiring a thorough medical exam to rule out mimickers.
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