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Elise Bornet

@elisebor.bsky.social
118 followers 252 following 2 posts

Microbiology, RNA, Evolution, Synthetic biology, and other hobbies Postdoc @Institut Pasteur

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Reposted by Elise Bornet
Youssef El Mouali @youssefelmouali.bsky.social · 07/05/2026
New paper out in @cp-cellhostmicrobe.bsky.social! Microbes evolving with modern lifestyles 🧬🦠 S. copri uses PerR to manage oxygen stress, but some strains acquired OxyR via HGT, boosting oxygen tolerance. These strains are enriched in industrialized populations. www.cell.com/cell-host-mi...
cell.com
Biogeography-associated emergence of enhanced oxygen tolerance in the abundant human gut commensal Segatella copri
El Mouali and Tawk et al. characterize the oxygen-tolerance response in the human gut-residing bacterium Segatella copri. They identified a subset of strains that acquired an additional oxygen regulat...
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 04/05/2026
New preprint from the Ghigo lab (@jmghigolab.bsky.social): crossfeeding B. theta <--> E. coli within a microfluidics system. Shows spatial structure and oxygen availability can qualitatively transform the nature and ecological outcome of microbial interactions. www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Elise Bornet
Vivek Mutalik @vivekmutalik.bsky.social · 04/12/2025
#microsky 😳 www.cell.com/cell-host-mi...
cell.com
A commensal bacterium secretes effector proteins to establish population heterogeneity in the gut
Zagieboylo and colleagues demonstrate that the human commensal Bacteroides thetaiotaomicron secretes two self-targeting proteins that induce heterogeneity within its own population. Differential expre...
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 01/12/2025
🔊 Interested in doing a PhD on RNA-binding proteins in an abundant microbiota species and becoming a member of the German Priority Programme “Illuminating Gene Functions in the Human Gut Microbiome”? Apply here: www.uni-wuerzburg.de/karriere/sin...
uni-wuerzburg.de
Job offer for a PhD student position at the Chair of Microbiology
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 09/09/2025
New preprint from the lab, in collaboration with Wenhan Zhu (U Vanderbilt): using dual RNA-seq during B. theta colonization of the host mucous layer, we identify IroR--an iron-response sRNA that tunes capsule expression and facilitates adaptation to iron limitation. doi.org/10.1101/2025.09.08.672848
doi.org
An RNA regulates iron homeostasis and host mucus colonization in Bacteroides thetaiotaomicron
Symbiotic bacteria in the human intestinal microbiota provide many pivotal functions to human health and occupy distinct biogeographic niches within the gut. Yet the molecular basis underlying niche-s...
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Elise Bornet @elisebor.bsky.social · 14/07/2025
Second that !!!! Super excited and honoured to see this work on Bactetoides morphotypes spotlighted by Qinnan Yang and Eric Martens in Trends in Microbiology.
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 11/07/2025
Congrats to Gianluca Prezza (@gprezza.bsky.social) for reveiving the 2025 PhD Award from the Friends of the Helmholtz Centre for Infection Research (HZI)!👏 The award honours excellent PhD theses from the field of life sciences at HZI partner universities. His thesis focused Bacteroides' RNA biology.
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Reposted by Elise Bornet
Cell Reports @cp-cellreports.bsky.social · 22/06/2025
Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
dlvr.it
Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron cells observed both in laboratory culture and inside the mammalian GI tract. The authors show that cell size is only partially dictated by cell-cycle progression and is associated with distinct gene expression programs that suggest metabolic differentiation.
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 17/06/2025
Our latest: www.cell.com/cell-reports/fulltext/S2211-1247(25)00615-1. Links Bacteroides cell size w/ gene expression. Protocol works even for single cells. 🦠 Shoutout to @elisebor.bsky.social, @emmanuel-saliba.bsky.social, @lbarquist.bsky.social, @jorg-vogel-lab.bsky.social, Till Strowig & KC Huang.
cell.com
Low-input RNA-seq suggests metabolic specialization underlying morphological heterogeneity in a gut commensal bacterium
Bornet et al. investigate the morphological heterogeneity of Bacteroides thetaiotaomicron cells observed both in laboratory culture and inside the mammalian GI tract. The authors show that cell size i...
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Elise Bornet @elisebor.bsky.social · 17/06/2025
Excited to share my PhD work! We used a low-input RNA-seq protocol to dig into what drives cell shape differences in Bacteroides thetaiotaomicron. Congrats and big thanks to all co-authors 🧫🧬.
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 14/02/2025
📣Fully funded PhD position available in our lab at @uniwuerzburg.bsky.social, in collaboration with Dr. Connolly at Newcastle University (@ruamicro.bsky.social). "Dissecting the RNA-centric landscape of microbiota-pathogen interactions in the gut”. 🦠 Apply here: www.uni-wuerzburg.de/karriere/sin...
uni-wuerzburg.de
PhD student position at the Chair for Microbiology
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Reposted by Elise Bornet
Lars Barquist @lbarquist.bsky.social · 04/02/2025
Interested in collecting, sharing, and interacting with large collections of bacterial functional genomics data (RNA-seq, Tn-seq/TraDIS, etc.)? Check out our new web platform, Micromix, with case studies for Salmonella and Bacteroides! 🧫🧬🖥️🧪 Thread 1/n academic.oup.com/gigascience/...
academic.oup.com
Micromix: web infrastructure for visualizing and remixing microbial ‘omics data
Abstract. Micromix is a flexible web platform for sharing and integrating microbial omics data, including RNA sequencing and transposon-insertion sequencin
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Reposted by Elise Bornet
Westermann Lab @westermannlab.bsky.social · 09/01/2025
Is it anything Hfq-like (RNA chaperone)? Or similar to CsrA (global translation modulator)? We don't know yet. But as it stands, Bacteroidota RRM proteins appear as excellent candidates to map post-transcriptional networks in a substantial fraction of the microbiota. www.nature.com/articles/s41...
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