imageimageHSPCs polarize in contact with bone marrow stromal cells constituting their niche. This study analyses the polarity of hematopoietic cells from AML patients using artificial micro-niches and...

Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.

The crosstalk between cell-cell and cell-matrix adhesions regulates stem cell fate. Here, the authors reveal a critical role for matrix viscosity in controlling this crosstalk, which they explain via ...