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Ed van Veen

@edvanveenphd.bsky.social
84 followers 227 following 13 posts

Double A Prof@UCLA. Women’s health researcher: ‘Roids, brains, and DNA. One of Forbes Canada's 47 expats who are exactly 47.

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Reposted by Ed van Veen
Kiran Soma @kiransoma.bsky.social · 23/09/2026
Congrats to Jordan Hamden and co-authors! Nice to see this one out. dx.plos.org/10.1371/jour...
dx.plos.org
The parental intestinal microbiome modulates systemic and local glucocorticoid levels in neonatal mice
Glucocorticoids (GCs) are steroid hormones predominately produced by the adrenal glands and secreted into the blood, but are also produced locally within some target tissues. During early development ...
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Reposted by Ed van Veen
Addgene @addgene.bsky.social · 09/09/2026
We love to see it! 👀 Neuro-seeER is a fluorescent reporter for tracking neuronal estrogen response dynamics in vivo. Thanks @endoeartha.bsky.social, @acara333.bsky.social, @edvanveenphd.bsky.social et al. for sharing! Learn more 👇 and find the plasmids here 🧬: www.addgene.org/browse/artic...
addgene.org
Addgene: A bifunctional optical reporter for tracking estrogen response dynamics in neurons.
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Ed van Veen @edvanveenphd.bsky.social · 22/09/2026
Me while writing: You know what this proposal needs? More abbreviations.
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Ed van Veen @edvanveenphd.bsky.social · 22/09/2026
Amazing work Dr. Cortes! This study has it all: pregnancy loss, the heat of the rhythms of the night, some real knockout data, and MATH!
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Ed van Veen @edvanveenphd.bsky.social · 03/09/2026
repeat-finder — find direct and inverted repeats in any sequence. So your plasmids don't recombine in bacteria. wobble-d — synonymously recode DNA so that you can get rid of those repeats. It works offline and is lightweight. Use it! Add to it! Or don't! Don't get your genes all untwisted!
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Ed van Veen @edvanveenphd.bsky.social · 03/09/2026
mutate-tn — when I'm designing mutant constructs with @genewiz.bsky.social, they want sequence in DNA format but I usually only know the amino acid mutation. mutate-tn takes a DNA sequence and amino acid mutation in that sequence and gives you back the DNA you need to make
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Ed van Veen @edvanveenphd.bsky.social · 03/09/2026
It's just a bunch of stuff I find useful when designing DNA, like: neutral-dna — generate DNA sequences that aren't predicted to bind transcription factors. Useful for letting DNA elements in a construct breathe without accidentally jamming a TATAA or something somewhere it doesn't belong
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Ed van Veen @edvanveenphd.bsky.social · 03/09/2026
1/5 I* made a command-line DNA toolkit called cedna: Captain Ed’s DNA tools. I named it this because I am a deeply unserious person. 🏴‍☠️🧬 *codex wrote it, but I was there too github.com/jevanveen/ce...
github.com
GitHub - jevanveen/cedna: Captain Ed's command-line tools for designing, editing, and analyzing DNA sequences
Captain Ed's command-line tools for designing, editing, and analyzing DNA sequences - jevanveen/cedna
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Ed van Veen @edvanveenphd.bsky.social · 31/08/2026
3/3 Huge thanks to @allenphilanthro.bsky.social for giving us the freedom to take a big swing at a risky idea. And special props to co-first author @endoeartha.bsky.social who will hopefully soon be running her own lab. We’re excited to get seeER out into the world and see what people do with it!
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Ed van Veen @edvanveenphd.bsky.social · 31/08/2026
2/3 All science is team science. Here, my lab wrangled the DNA, @correalab.bsky.social lab brought the real neuroendocrinology, @neurrriot.bsky.social lab brought the live-imaging wizardry, and @kiransoma.bsky.social lab brought gold-standard steroid hormone measurements.
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Ed van Veen @edvanveenphd.bsky.social · 31/08/2026
1/3 Our seeER paper is out in Neuron! 🎉 We built a genetically encoded reporter to see when & where estrogen receptors are actually signaling in the brain, not just where the receptors are expressed. Paper: www.cell.com/neuron/fullt... Resources: jevanveen.github.io/resources/
cell.com
A bifunctional optical reporter for tracking estrogen response dynamics in neurons
Cara, Guthman, et al. present neuro-seeER, an optical tool for monitoring how neurons respond dynamically to the hormone estrogen. By tracking these dynamics across the reproductive cycle in female mi...
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Reposted by Ed van Veen
eartha mae @endoeartha.bsky.social · 28/08/2026
Extremely proud to share @acara333.bsky.social and my new paper, out today in @cp-neuron.bsky.social, where we develop a new fluorescent reporter of neural responses to estrogen! 🔬 paper 📝: www.cell.com/neuron/fullt... addgene page 🧬: www.addgene.org/254753/ #neuroskyence 🧪 1/10
graphical abstract of the manuscript depicting pink estrogen-sensitive neurons with a subset of their nuclei colored in green. These green nuclei represent estrogen receptor dependent neural gene transcription, tracked via the expression of a destabilized GFP with a 2 hour half-life. At top, in green is shown a cartoon of the neural response to estrogen across two estrous cycles, and below there is a cartoon of a mouse implanted with an optic fiber for in vivo imaging.
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Reposted by Ed van Veen
Annegret Falkner @neurrriot.bsky.social · 30/08/2026
In vivo estrogen imaging is here! Construct is up on addgene, and lots of other imaging constructs are currently in validation. Get in touch if you want advice about how to set up. We are happy to help! Thanks so much to @alleninstitute.org and @onemindorg.bsky.social for their support 😍
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Ed van Veen @edvanveenphd.bsky.social · 28/08/2026
You are the GOAT Eartha!
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Ed van Veen @edvanveenphd.bsky.social · 21/01/2026
If anyone doing Alzehiemer's research is looking for a talented post-doc, please contact me at vanveen@UCLA.edu . Due to a recent unexpected death, a successful post-doc in my home department is on the job market
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Ed van Veen @edvanveenphd.bsky.social · 22/12/2025
Me too. I like to understand one thing rather than describing everything
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Reposted by Ed van Veen
Annegret Falkner @neurrriot.bsky.social · 16/12/2025
Want to track the dynamics of estrogen in the brain across long periods of time? New paper as part of very fun collab with team UCLA Ed Van Veen and Steph Correa! We use a specialized optical reporter and show that this is possible and actually very easy! www.biorxiv.org/content/10.6...
biorxiv.org
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Reposted by Ed van Veen
Luke Remage-Healey @healeylab.bsky.social · 16/12/2025
@correalab.bsky.social at it again!!
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Ed van Veen @edvanveenphd.bsky.social · 16/12/2025
The preprint is out :) thank you @allenphilanthro.bsky.social www.biorxiv.org/content/10.6...
biorxiv.org
A bifunctional optical reporter for tracking estrogen response dynamics in neurons
Estrogens are inherently dynamic signaling molecules whose fluctuations induce profound shifts in physiology and behavior. However, methods for tracking the dynamics of estrogen action in vivo are lim...
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