In this Perspective, the international PAINDIFF Network makes 13 recommendations for studying sex and gender as variables in preclinical, clinical and translational pain research that are applicable a...

Current evidence does not indicate a clinically important increase in the likelihood of autism spectrum disorder, ADHD, or intellectual disability in children of pregnant individuals who use paracetam...

As a leading UK research institute in applied mathematics, The Institute for Mathematical Innovation (IMI) adds value and impact to research by creating interdisciplinary connections through modelling...

BackgroundMultiple sclerosis (MS) is a chronic disease of the central nervous system, most commonly affecting individuals in early adulthood. Uncertainty abo...

Background Globally, around 30% of people live with long-term (‘chronic’) pain, with known impact on wellbeing, economic and social lives. Despite increasing attention to contextual and psychosocial a...

A landmark review shows cognitive behavioural therapy (CBT) reduces the emotional burden of pain and makes measurable changes in brain activity.

My first real experience of prolonged pain was when I was 16 when I had a month of unexplained pains in my hands and feet following a bout of viral pneumonia. I would get similar extended periods o…

Introduction: Few studies compare differences in the use of nonpharmacologic interventions (NPIs) between those with high-impact chronic pain (HICP) and low-impact chronic pain (LICP) or describe dif...